the community site for and by developmental biologists

New data reveals gene expression during mouse embryo development

Posted by on September 29th, 2016

This article was originally posted on the DMDD website dmdd.org.uk Knowing the ‘normal’ expression of genes during embryo development is key to understanding the differences that occur due to genetic mutations. As part of work to understand the underlying transcriptional processes for developing embryos from knockout mouse lines, DMDD has now released a gene expression[…]

The people behind the papers #4

Posted by on September 26th, 2016

In this series, we interview the people behind some of the most exciting recent papers in developmental biology and related fields, to give context to the work and find out how the story came together.   Today we feature an upcoming paper in Cell Stem Cell that investigates the role of Schwann cell precursors in the multi-tissue regeneration of the[…]

Dolly @ 20: My day at the symposium marking her legacy

Posted by on September 23rd, 2016

The 5th of July 1996 marked the birth of the world’s most famous sheep, Dolly. A scientific revelation, she was the first mammal to be cloned from an adult somatic cell through nuclear transfer. Earlier this month, scientists from far and wide gathered at the Roslin Institute in Edinburgh for a special one-day symposium dedicated[…]

Seeking out the sweet spot in cancer therapeutics: an interview with Lewis Cantley

Posted by on September 23rd, 2016

  “…had you told me when I was 25 years old that I would be the director of a cancer center I would have been incredulous, given that I was totally into chemistry”   This is an extract from an interview that originally appeared in Disease Models and Mechanisms (available here Open Access) Paraminder Dhillon,[…]

The culture of research and the future of the science system

Posted by on September 22nd, 2016

On Monday, September 19th, a group of early career researchers from across the UK and across the sciences gathered at the Royal Society in London to discuss the future of research at a one day conference. As the Node’s Community Manager, I was lucky enough to be allowed to join in. I’ve only recently left research, and[…]

New Technology in Medicine

Posted by on September 22nd, 2016

Technology is quickly changing many parts of medicine, giving people more power to take charge of their health care. Taking isotope labeled peptides as an example, stable isotope labeled peptides have been widely applied in the nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS). The combination of SIL peptides with NMR spectroscopy allow for[…]

Would peer review work better if reviewers talked to each other? An interview for Retraction Watch

Posted by on September 21st, 2016

As you may have seen, we at Development have recently announced a change to our peer review process, introducing a cross-referee commenting step. This should be in place within the next week or two, and we’re hoping it will help us to make better decisions on papers, and to make the revision process easier for[…]

Gene regulation, evolution and the exploitation of new habitats

Posted by on September 21st, 2016

Changes in body organ morphology have allowed animals to better exploit diverse habitats. As organ morphology is under genetic control, genetic modifications provide the basis for the wide range of morphologies. However, as our knowledge of the genetic basis of phenotypic diversification in evolution has focused mostly on quantitative traits, it is not clear how[…]

Where does blood come from in the first place and how is it made?

Posted by on September 14th, 2016

Commentary on Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells in Developmental Cell, Volume 38, Issue 4, p358–370, 22 August 2016   Each of us has around 6 pints of blood. The blood contains a number of different types of cells, including oxygen-transporting red blood cells, disease-protecting white[…]