the community site for developmental biologists

In Development this week (Vol. 142, Issue 15)

Posted by on August 4th, 2015

Here are the highlights from the current issue of Development:   CHD4 restrains gene expression during lineage specification The first lineage-specification event in the early embryo generates the inner cell mass (ICM), which later gives rise to the embryo proper, and the trophectoderm (TE), which then develops into extra-embryonic tissues. This fate decision is known[…]

The importance of indifference in scientific research

Posted by on August 3rd, 2015

This essay by Martin Schwartz was originally published in the Journal of Cell Science.   Current issues regarding scientific ethics have focused for the most part on regulations governing research and publication. I suggest that the internal process by which we separate self interest from the scientific process is a crucial and neglected part of training.[…]

This month on the Node- July 2015

Posted by on August 1st, 2015

July was a really exciting month on the Node, as we launched our brand new look and celebrated our 5th anniversary! Here are some of the highlights:   Happy birthday to the Node: The Node’s birthday gift to itself was a brand new look and logo. Check out our first post of the month for[…]

Question of the month- interdisciplinary research

Posted by on July 29th, 2015

Developmental biology is becoming increasingly interdisciplinary, as biologists team up with physicists and mathematicians to address new and classical problems in the field from a new perspective. But should we all be pursuing such an approach or is there still room for ‘pure’ developmental biology approaches? Should we incorporate more physics/mathematics modules in the training of[…]

From our sister journals- July 2015

Posted by on July 28th, 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.         Drosophila helps to elucidate the effects of radiation therapy Children who are exposed to cranial radiation therapy (CRT) to treat brain tumours are at increased risk later in life for neurocognitive, motor and seizure disorders.[…]

Embracing risk

Posted by on July 27th, 2015

This editorial by Ross Cagan was first published in Disease Models & Mechanisms.   I entered the science field because I imagined that scientists were society’s “professional risk takers”, that they like surfing out on the edge. I understood that a lot of science – perhaps even most science – has to be a solid exploration[…]

Mole’s Wow! So now you have your own lab! Part IV – The fit

Posted by on July 27th, 2015

This cartoon was first published in the Journal of Cell Science. Read other articles and cartoons of Mole & Friends here.     Part I- ‘The imposter’ Part II- ‘The teaching monster’ Part III- ‘The Pact’ (+2 rating, 2 votes) Loading…

European Advanced School for Mouse Phenogenomics – pushing the boundaries of mouse genetics

Posted by on July 24th, 2015

The laboratory mouse has been a popular model in mammalian biology for obvious reasons and it has contributed to a number of landmark discoveries in biomedical research. Despite this, few courses and summer schools – which train future leaders in this field – focus on mouse genetics. Phenomin, a large-scale French national infrastructure for biology[…]

In Development this week (Vol. 142, Issue 14)

Posted by on July 21st, 2015

Here are the highlights from the current issue of Development:   HIF1α muscles in on regeneration During early development, skeletal muscle stem/progenitor cells (SMSPCs) are thought to reside in low O2 levels but how this hypoxic environment affects myogenesis in vivo is unclear. Here, Celeste Simon and colleagues investigate the role of hypoxia inducible factor[…]