the community site for and by developmental biologists

Question of the month- Ethical issues in life sciences publishing

Posted by on April 28th, 2016

In the last few years, the life sciences have been plagued by cases of scientific misconduct which led to corrections,  retractions and, to some extent, in a lack of trust on the scientific record. This has encompassed a variety of issues, from  manipulation to fabrication of data, from inappropriate use of statistics (unintentional or otherwise) to[…]

Untangling developmentally programmed obesity: role of the serotonin system

Posted by on April 27th, 2016

This post highlights the approach and findings of a new research article published in Disease Models and Mechanisms (DMM): ‘5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats’. This feature was written by Richard Seeber as part of a graduate level seminar at The University of Alabama (taught by DMM Editorial Board[…]

Scratching the surface of a rainbow

Posted by on April 26th, 2016

  Why some vertebrates like salamanders and zebrafish are able to regenerate complex tissues while humans cannot is a question that has fascinated biologists for centuries. Understanding how and why regeneration occurs in these animals can inspire novel treatment strategies for regenerative medicine. At the cellular level, the regeneration process is driven by dynamic activities[…]

All movies of the 2016 BSCB/BSDB Spring Meeting

Posted by on April 23rd, 2016

In 2016 the BSCB/BSDB Spring conference has yet again been a great success, and many prizes were announced, amongst them the BSDB’s Waddington, BSCB’s Hooke, BSCB’s Women in Cell Biology Early Career Award, BSDB’s Cheryll Tickle and BSDB’s Beddington medals. See below movies of the first four of the five medal talks and find more[…]

Transdifferentiation and Tissue Plasticity in Cardiovascular Rejuvenation: a workshop about protein teamwork, regeneration programs and tiny needles

Posted by on April 21st, 2016

It was on the 7th of February of 2016 when 20 leading scientists from all over the world headed to the historic Wiston House in West Sussex, England, to spend four days in focused atmosphere discussing new insights in cardiovascular research: the workshop for Transdifferentiation and Tissue Plasticity in Cardiovascular Rejuvenation. Supported by the Company[…]

Interview with Beddington medal winner Elena Scarpa

Posted by on April 21st, 2016

Every year, the British Society for Developmental Biology (BSDB) awards the Beddington Medal to the best PhD thesis in developmental biology. The 2016 award went to Elena Scarpa, who did her PhD with Roberto Mayor at University College London (UCL). We caught up with Elena at the BSCB/BSDB Spring meeting, and we asked her about[…]

Mole’s Wow! So now you have your own lab! Part IX – The big fight

Posted by on April 20th, 2016

This cartoon was first published in the Journal of Cell Science. Read other articles and cartoons of Mole & Friends here.     Part I- ‘The imposter’ Part II- ‘The teaching monster’ Part III- ‘The Pact’ Part IV- ‘The fit’ Part V- ‘The plan’ Part VI- ‘FCTWAWKI’ Part VII- ‘Beaten and bruised’ Part VIII- ‘Money Matters’ (+1[…]

Gills, fins and the evolution of vertebrate paired appendages

Posted by on April 19th, 2016

The origin of paired fins is a major unresolved issue in vertebrate evolutionary biology, and has been a topic of debate among palaeontologists, comparative anatomists and developmental biologists for over a century. Central to any question of “evolutionary origins” is the concept of homology: the sharing of features due to common ancestry. Homology may explain[…]

In Development this week (Vol. 143, Issue 8)

Posted by on April 19th, 2016

Here are the highlights from the current issue of Development:   The origins of lung macrophages revealed Tissue-resident macrophages are phagocytic cells that are essential for the response to injury and infection. Both within and between tissues, macrophages can show distinct characteristics, but are these attributes developmentally defined or determined by the microenvironment? In the[…]