the community site for and by developmental biologists

Meet Evan Brooks – The 2017 Choose Development! Fellow selected to spend one week with the Embryology Course

Posted by on July 21st, 2017

Evan Brooks is a rising senior at North Carolina State University. For the past two years, he has worked in the lab of Nanette Nascone-Yoder studying the developmental mechanisms of cardiac left-right asymmetry using Xenopus as his model system. Evan was awarded a Choose Development! Fellowship from the Society of Developmental Biology to conduct two[…]

The people behind the papers – Ivette Olivares-Castiñeira & Marta Llimargas

Posted by on July 21st, 2017

The Drosophila tracheal system is a powerful model for understanding the genetic and cell biological control of tubulogenesis. In their new PLoS Genetics paper, Ivette Olivares-Castiñeira and her PI Marta Llimargas of the Molecular Biology Institute of Barcelona connect EGFR signalling to intracellular cell trafficking during tracheal morphogenesis. We caught up with Marta and Ivette to hear the story behind[…]

9.5 million knockout mouse embryo images now available

Posted by on July 20th, 2017

A new set of DMDD embryo and placenta data has been released, taking our total dataset to 9.5 million images of around 1300 embryos. DMDD is a primary screen of embryonic lethal knockout mice, and all data can be freely accessed at dmdd.org.uk. Detailed phenotypes are available for embryos from 73 different knockout lines, and[…]

The people behind the papers – Kimberly McArthur & Joseph Fetcho

Posted by on July 20th, 2017

Development depends on cells coming together in the right place to form functioning tissues. Our latest paper in this series was published recently in Current Biology and asks what happens to the structure and function of the nervous system when motor neuron migration – and hence final position – is disrupted. We caught up with postdoc[…]

Unfolding collaboration

Posted by on July 18th, 2017

We came across this video from EuroStemCell describing a project that aimed to increase public awareness of stem cell biology, as well as encourage scientists to get involved in public engagement and interact with other professionals along the way. In their introduction to the video, EuroStemCell give us the background:   “Creative public engagement initiatives are[…]

In Development this week (Vol. 144, Issue 14)

Posted by on July 18th, 2017

Here are the highlights from the current issue of Development:   Computing branching pattern complexity Bile – a fluid that aids digestion – is transported from the liver to the intestine through the bile duct. Bile reaches the bile duct itself via a complex, highly branched structure called the intrahepatic biliary network. This network spreads[…]

A New (and open-access!) Antibody Search Platform: BenchSci

Posted by on July 13th, 2017

Antibodies are one of the most commonly used research reagents. However, due to their innate variability, finding the right antibody can be a challenge. Scientists devote a significant amount of time sifting through the literature to find antibodies that have been shown to work under specific experimental contexts matching their research interests. This process often[…]

Cells are much smarter than we give them credit for

Posted by on July 13th, 2017

In the very earliest stages of life, mammalian cells multiply and form the embryo. New research from the University of Copenhagen suggests that this process might be much simpler than we thought. The development of the embryo can be cut down to the cell’s ability to count their neighboring cells. The article ‘Four simple rules[…]

Four recent science art & photography announcements

Posted by on July 13th, 2017

Worm art at #Worm17 Each year at the International C. elegans Conference Ahna Skop organises a Worm Art Show with winners selected by the meeting participants (find out more about the history of the show here).  2017’s winners have just been announced – read about them over at the GSA’s Genes to Genomes blog (a great site for your bookmarks[…]