the community site for and by developmental biologists

Plant “Velcro” holds it all together

Posted by on June 27th, 2016

  Plant hairs or trichomes mean little to most people until they bite into a furry skinned peach or prick their finger on a rose bush thorn, but in the plant kingdom these versatile epidermal structures perform many essential functions that are attributable to their physical shape, location, density and sometimes chemical composition. Next time[…]

YEN 2016 review

Posted by on June 26th, 2016

My informal review of YEN this year is by necessity a bit rushed but, for what it is, here it is. Most reviews are very short and pithy/jealous and only exist for some of the talks where, for a combination of good and bad reasons, I paid attention (I have tried to make this review[…]

Model Organism Database funding is in trouble: Let your voice be heard

Posted by on June 23rd, 2016

  Model Organisms such as yeast, worm, fly, fish, rat, and mouse are key drivers of biological research, providing manipulable and cost-effective experimental systems that continuously yield fundamental insights into human biology and health. These discoveries rely on the accumulated wealth of genetic, genomic and cellular knowledge for each organism, which is made accessible via[…]

Developing Future Biologists 2016: Discovering the new generation of scientists!

Posted by on June 22nd, 2016

Developing Future Biologists (DFB) is a student-led organization at University of Michigan dedicated to ensure that the next generation of biologists regardless of race, gender, or socioeconomic status have the opportunity to learn the core concepts of developmental biology. During the last week of May, DFB held its 2nd successful week-long short course aiming to inform students[…]

A day in the life of a gar lab

Posted by on June 21st, 2016

My name is Martin Minařík and I am a PhD student in Robert Cerny’s lab at Charles University in Prague, Czech Republic. Our lab focuses mostly on the development of non-teleost fishes, namely bichirs, sturgeons, and gars. The advantage of having these animals as model organisms is that their breeding seasons alternate throughout the year,[…]

Reproducibility: a pathological perspective

Posted by on June 20th, 2016

” the ability to reproduce experimental findings remains essential for the forward movement of science and the application of laboratory findings to the clinic”   This is an extract from a Special Article article that originally appeared in Disease Models and Mechanisms (available here Open Access) Paul Schofield, Jerrold Ward, John P. Sundberg   Reproducibility of data from[…]

Hello from Aidan!

Posted by on June 14th, 2016

I’m happy to introduce myself as the Node’s new Community Manager, taking up the reins from Cat Vicente, who said goodbye recently, and left this unique site in great shape. I’ve come to the Node from the lab bench, recently as a postdoc with Nick Brown in Cambridge, and before that as PhD student with[…]

In Development this week (Vol. 143, Issue 12)

Posted by on June 14th, 2016

Here are the highlights from the current issue of Development:   A distinct cartilage programme for bone regeneration Bone healing, for example fracture repair in humans, often involves a cartilage intermediate but how this tissue is induced and contributes to healing is unclear. Here, Gage Crump and co-workers show that regeneration of the zebrafish jawbone[…]

Sweetening with a pinch of salt: maximized Cas9 efficiency in zebrafish

Posted by on June 14th, 2016

  Alexa Burger, Mosimann lab, Institute of Molecular Life Sciences, University of Zürich, Switzerland. When I first heard about the “new” genome editing method in early 2013 called CRISPR-Cas9, I thought: “Never ever again will I work with targeted nucleases!” Now it’s mid-2016, we published our approaches to maximize Cas9 effectiveness in zebrafish with Development[…]