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The Node is a place to share news about and with the developmental biology community around the world. If this is your first time on the site, check out this introduction to the Node. You can also find out more about us, and sign up to contribute.
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Node update
Posted by the Node on July 29th, 2010
A few bits of news and reminders about the Node, just to keep you all up to date: -We’ll be interviewing Jorge Cham, creator of the grad student comic Piled Higher and Deeper (PHD), this weekend. Do you have any questions you’d like to ask him? I asked for input via our Twitter account, and […]
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Embryological Discovery in Woods Hole : Vertebrates
Posted by Sorrel Bickley on July 27th, 2010
We are in our last week of the Embryology Course at Wood’s Hole now, and currently working on annelid and squid embryos. Things are still going at a frenetic pace but I’d like to take this chance to talk a little more about some of the work we did using vertebrates. The course covers many […]
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In Development this week (Volume 137, Issue 16)
Posted by Seema Grewal on July 27th, 2010
Here are the highlights from this week’s issue of Development: Lymphatic networks follow arterial lead The vertebrate lymphatic system consists of lymphatic vessels, which collect fluid from the tissues and return it to the blood, and lymph nodes, which are involved in immune defence. Lymphatic vessels, like blood vessels, form a complex vascular network, but what guides the development of […]
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The Maggot Meeting-2010
Posted by Tetyana on July 26th, 2010
Greetings! It’s been an overcast, windy and gloomy Monsoon here in Bangalore, but the past few weeks at NCBS have been bright and exciting! The “Maggot Meeting - 2010”: Neural Circuits and Behaviour is currently on till the 27th of July and I look forward to the seminars and interactive discussions with eminent scientists. Early […]
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Too many postdocs and PhD students?
Posted by Eva Amsen on July 23rd, 2010
There was a nice piece on the Naturejobs site this week, written by postdoc Katherine Sixt. She describes how she started to realize that not every postdoc will eventually become a professor. There simply aren’t enough positions available, so postdocs should look at other careers. But as a postdoc, and even as a PhD student, […]
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Science on Screen
Posted by Eva Amsen on July 20th, 2010
If you’re annoyed by the unconvincing lab work on shows like CSI, and would like to show the world what real scientists are like, why not make a film yourself? You’d be surprised to find out how many films by or with scientists there are, both fiction and non-fiction. This month alone, two organizations involved […]
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Development Editors Meeting
Posted by Eva Amsen on July 19th, 2010
On July 9, the editors of Development met in Strasbourg (or joined over the phone) for a meeting. Because Development’s editors are spread out all over the world, these meetings are a rare opportunity to get everyone together to discuss the journal. Editors all get a chance to share ideas they have for the journal, […]
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An interview with Thomas Lecuit
Posted by Eva Amsen on July 16th, 2010
(This interview by Kathryn Senior originally appeared in Development on July 13) Thomas Lecuit heads up a multidisciplinary team of 10 scientists at the Developmental Biology Institute of Marseilles (IBDML) in France. He is deeply interested in how the tissues that form our organs acquire and maintain their proper architecture and has special expertise in […]
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Embryological Discovery in Woods Hole
Posted by Ann Grosse on July 14th, 2010
Three weeks ago, we joined a group of twenty-four students from around the world arriving in the small town of Woods Hole, Massachusetts. We were strangers from all sorts of backgrounds, but we were drawn together by one commonality – a deep interest in developmental biology. We are all here to participate in the Marine […]
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Some tips for reading the Node
Posted by the Node on July 14th, 2010
The Node has been officially live for almost four weeks now, and we’ve seen visitor numbers and registrations go steadily up. As with most websites, there are far more silent readers than people who are actively writing, so here are a few tips on keeping up to date with the Node: If you don’t want […]
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- Spine-tingling new role for Sall4 [IN THIS ISSUE]
- Ageing thymus out-FOXed [IN THIS ISSUE]
- Muscling in on stem cell hierarchy [IN THIS ISSUE]
- Nucleolus precursor body makeover [IN THIS ISSUE]
- Moss stem cells do it differently [IN THIS ISSUE]
- Change of heart for RA signalling [IN THIS ISSUE]
- The evolution and conservation of left-right patterning mechanisms [HYPOTHESIS]
- The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease [REVIEW]
- Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus [RESEARCH ARTICLES]
- The maternal nucleolus plays a key role in centromere satellite maintenance during the oocyte to embryo transition [RESEARCH ARTICLES]
- The egg membrane microdomain-associated uroplakin III-Src system becomes functional during oocyte maturation and is required for bidirectional gamete signaling at fertilization in Xenopus laevis [RESEARCH ARTICLES]
- Development of five digits is controlled by a bipartite long-range cis-regulator [RESEARCH ARTICLES]
- Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord [RESEARCH ARTICLES]
- Type I TARPs promote dendritic growth of early postnatal neocortical pyramidal cells in organotypic cultures [RESEARCH ARTICLES]
- Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination [RESEARCH ARTICLES]
- Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis [RESEARCH ARTICLES]
- A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication [RESEARCH ARTICLES]
- Pulses of Notch activation synchronise oscillating somite cells and entrain the zebrafish segmentation clock [RESEARCH ARTICLES]
- Genetically encoded molecular probes to visualize and perturb signaling dynamics in living biological systems [Articles of interest in other COB journals]
- Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours [Articles of interest in other COB journals]
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- Editorial Board
- Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers
- Hipk promotes photoreceptor differentiation through the repression of Twin of eyeless and Eyeless expression
- Unc45b is essential for early myofibrillogenesis and costamere formation in zebrafish
- Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells
- Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear
- Mesodermal Nkx2.5 is necessary and sufficient for early second heart field development
- Maternal bias and escape from X chromosome imprinting in the midgestation mouse placenta
- Editorial Board
- Do the BEAF insulator proteins regulate genes involved in cell polarity and neoplastic growth?
- Lhx1 is required in Müllerian duct epithelium for uterine development
- A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans
- Cleavage of the Drosophila screw prodomain is critical for a dynamic BMP morphogen gradient in embryogenesis
- Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads
- CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways
- The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis
- Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones
- Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages
- Editorial Board
- Development and evolution of vertebrate cranial placodes
- Setting appropriate boundaries: Fate, patterning and competence at the neural plate border
- Establishing the pre-placodal region and breaking it into placodes with distinct identities
- Neural crest and placode interaction during the development of the cranial sensory system
- Signaling mechanisms controlling cranial placode neurogenesis and delamination
- Sensational placodes: Neurogenesis in the otic and olfactory systems
- The development of lateral line placodes: Taking a broader view
- The evolutionary history of vertebrate cranial placodes – I: Cell type evolution
- The evolutionary history of vertebrate cranial placodes II. Evolution of ectodermal patterning
- Resident progenitors, not exogenous migratory cells, generate the majority of visceral mesothelium in organogenesis
- Editorial Board
- Impact
- Why you should publish your papers in Developmental Biology
- SDB 2014 Meeting Announcement
- Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death
- Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis
- Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis
- Epigenetic regulation of oogenesis and germ stem cell maintenance by the Drosophila histone methyltransferase Eggless/dSetDB1
- Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development
- The bristle patterning genes hairy and extramacrochaetae regulate the development of structures required for flight in Diptera
- Retraction notice to “The human placenta is a hematopoietic organ during the embryonic and fetal periods of development” [Dev. Biol. 327 (2009) 24–33]
- Ecdysone differentially regulates metamorphic timing relative to 20-hydroxyecdysone by antagonizing juvenile Hormone in Drosophila melanogaster
- Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney
- Peroxisomal membrane channel Pxmp2 in the mammary fat pad is essential for stromal lipid homeostasis and for development of mammary gland epithelium in mice
- Cell signaling during development of Dictyostelium
- Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear
- Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning
- The PAF1 complex is involved in embryonic epidermal morphogenesis in Caenorhabditis elegans
- Neuroblast lineage identification and lineage-specific Hox gene action during postembryonic development of the subesophageal ganglion in the Drosophila central brain
- miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells
- Editorial Board
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- Dystrophic muscle environment induces changes in cell plasticity [Perspectives]
- DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos [Reviews]
- The diabetes gene Hhex maintains {delta}-cell differentiation and islet function [Research Communications]
- Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e [Research Communications]
- HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles [Research Papers]
- miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGF{beta} and Wnt signaling [Research Papers]
- ATR checkpoint kinase and CRL1{beta}TRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks [Research Papers]
- Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression [Research Papers]
- Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress [Research Papers]
- Root growth is modulated by differential hormonal sensitivity in neighboring cells [Research Papers]
- Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin [Errata]
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