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The Node is a place to share news about and with the developmental biology community around the world. If this is your first time on the site, check out this introduction to the Node. You can also find out more about us, and sign up to contribute.
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Exhausted but satisfied
Posted by Kim Cooper on March 31st, 2012
The breakfast bell rang early this morning, so I’ve only just gotten my shower this evening which is a good thing since I was filthy and covered in sand. We headed back to the spot where we set traps last night, and lo and behold I think we only lost one. And I could be […]
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Stairway to Learning
Posted by Smrithi on March 30th, 2012
When I stepped into the Institute of Genetics, Mainz, I stepped into the world of neural development - I was like Aladdin in the Cave of Wonders! It was all so new to me - so exciting, and so much to learn! Prof. Gerhard Technau’s group worked on different aspects of Drosophila neural development - […]
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This Month on the Node – March 2012
Posted by Eva Amsen on March 30th, 2012
Money appears to have been the main topic of conversation this month. In the past few weeks, we’ve had a glimpse into the status of science funding in countries around the world. Paul O’Neill shared some news about the current funding situation in Japan, where government advisors recommended amalgamation of the main science bodies to […]
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Wildlife abounds, but jerboas?
Posted by Kim Cooper on March 29th, 2012
This morning after a breakfast of fermented tofu on steamed buns, boiled peanut and rice soup, spicy strands of seaweed, and a plate of mixed onion, peppers, and tomato in vinegar, we headed off in the jeep in search of the right kind of desert for jerboas. I knew one of the places where we’d […]
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Banners
Posted by the Node on March 28th, 2012
If you’ve recently visited our Facebook page, you may have already seen them, but we have some new banners - of both the physical and digital kind. First of all, we have a new banner to take to conferences. If you’re going to some of the conferences where The Company of Biologists has a stand, […]
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Nihao from Xinjiang
Posted by Kim Cooper on March 28th, 2012
I have sprung up again in China. It’s time for another field collection of jerboa embryos in far northwestern China (Xinjiang), and since this is the reason Eva invited me to contribute to the Node, I figure it is finally time for me to oblige. The last couple of days were eventful. Friday morning I […]
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Post-doctoral position in Drosophila hematopoiesis: deciphering the niche function
Posted by vincent on March 20th, 2012
A 3 years post-doctoral position is immediately available in the laboratory of Michèle Crozatier and Alain Vincent, at the Centre de Biologie du Développement CNRS/Toulouse University, France. One main topic of the lab concerns Drosophila hematopoiesis, the hematopoietic niche and the plasticity of cell fates in the lymph gland (http://www-cbd.ups-tlse.fr/spip.php?rubrique53). The candidate will further explore […]
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In Development this week (Vol. 139, Issue 8)
Posted by Seema Grewal on March 20th, 2012
Here are the highlights from the current issue of Development: Chewing the Fat over PCP and growth The Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP) but also inhibits the overgrowth of imaginal discs by activating the Hippo pathway. The intracellular domain (ICD) mediates much of Ft activity, but are its PCP and Hippo […]
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FlyBase 2012 User Survey
Posted by Josh Goodman on March 20th, 2012
Dear Colleagues, FlyBase has begun to plan for the competitive renewal of FlyBase funding, which will be submitted to NIH in several months. EXTENSIVE INPUT from the community of FlyBase users is invaluable in two ways. (1) It is a crucial source of input to help us determine our priorities for the next five year period. (2) The […]
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An interview with José Xavier Neto
Posted by Eva Amsen on March 20th, 2012
(This interview originally appeared in Development.) The Latin American Society for Developmental Biology (LASDB) is getting ready for their Sixth International Meeting, which will be held in Montevideo, Uruguay, from April 26th to 29th, 2012. To find out more about the society, and about developmental biology in Latin America, we talked to LASDB president José […]
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- Invadosomes: aiding axonal invasion [IN THIS ISSUE]
- Taking the strain out of stem cell renewal [IN THIS ISSUE]
- Reporting on {beta}-catenin in the vasculature [IN THIS ISSUE]
- PUB4 calls time on root cell division [IN THIS ISSUE]
- Reaching out - the many faces of science outreach [SPOTLIGHT]
- Mathematically guided approaches to distinguish models of periodic patterning [HYPOTHESIS]
- Building a plant: cell fate specification in the early Arabidopsis embryo [REVIEW]
- Regulation of ECM degradation and axon guidance by growth cone invadosomes [RESEARCH ARTICLES]
- {beta}-catenin-dependent transcription is central to Bmp-mediated formation of venous vessels [RESEARCH ARTICLES]
- DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos [RESEARCH ARTICLES]
- ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination [RESEARCH ARTICLES]
- A transient wave of BMP signaling in the retina is necessary for Muller glial differentiation [RESEARCH ARTICLES]
- Surrounding tissues canalize motile cardiopharyngeal progenitors towards collective polarity and directed migration [RESEARCH ARTICLES]
- Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea [RESEARCH ARTICLES]
- A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face [RESEARCH ARTICLES]
- SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice [RESEARCH ARTICLES]
- Selective synaptic targeting of the excitatory and inhibitory presynaptic organizers FGF22 and FGF7 [Articles of interest in other COB journals]
- The microRNA miR-17-3p inhibits mouse cardiac fibroblast senescence by targeting Par4 [Articles of interest in other COB journals]
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- Editorial Board
- Differential pleiotropy and HOX functional organization
- A method for using direct injection of plasmid DNA to study cis-regulatory element activity in F0 Xenopus embryos and tadpoles
- Developmental alterations of the C. elegans male anal depressor morphology and function require sex-specific cell autonomous and cell non-autonomous interactions
- PLR-1, a putative E3 ubiquitin ligase, controls cell polarity and axonal extensions in C. elegans
- Mechanics of blastopore closure during amphibian gastrulation
- CSN maintains the germline cellular microenvironment and controls the level of stem cell genes via distinct CRLs in testes of Drosophila melanogaster
- Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT
- Nf2–Yap signaling controls the expansion of DRG progenitors and glia during DRG development
- Three-dimensional cultures of trophoblast stem cells autonomously develop vascular-like spaces lined by trophoblast giant cells
- Molecular characterization of the apical organ of the anthozoan Nematostella vectensis
- Znf385C mediates a novel p53-dependent transcriptional switch to control timing of facial qbone formation
- Fgf10 is required for specification of non-sensory regions of the cochlear epithelium
- Ecdysone response gene E78 controls ovarian germline stem cell niche formation and follicle survival in Drosophila
- Gene expression ontogeny of spermatogenesis in the marmoset uncovers primate characteristics during testicular development
- Pluripotent stem cell derived cardiovascular progenitors – a developmental perspective
- Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms
- RhoGAP68F controls transport of adhesion proteins in Rab4 endosomes to modulate epithelial morphogenesis of Drosophila leg discs
- The heparan sulfate-modifying enzyme glucuronyl C5-epimerase HSE-5 controls Caenorhabditis elegans Q neuroblast polarization during migration
- Loss of function of the yellow-e gene causes dehydration-induced mortality of adult Tribolium castaneum
- Co-expression of the transcription factors CEH-14 and TTX-1 regulates AFD neuron-specific genes gcy-8 and gcy-18 in C. elegans
- microRNAs regulate β-catenin of the Wnt signaling pathway in early sea urchin development
- Ontogeny of the mouse vocal fold epithelium
- Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration
- The organizer in evolution–gastrulation and organizer gene expression highlight the importance of brachyury during development of the coral, Acropora millepora
- Editorial Board
- The BED finger domain protein MIG-39 halts migration of distal tip cells in Caenorhabditis elegans
- Pox neuro control of cell lineages that give rise to larval poly-innervated external sensory organs in Drosophila
- Pax8 and Pax2 are specifically required at different steps of Xenopus pronephros development
- Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development
- The ABC transporter, AbcB3, mediates cAMP export in D. discoideum development
- Zebrafish Rab5 proteins and a role for Rab5ab in nodal signalling
- A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation
- Sox21 regulates the progression of neuronal differentiation in a dose-dependent manner
- Stochasticity and stereotypy in the Ciona notochord
- Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development
- Nucleolus-like bodies of fully-grown mouse oocytes contain key nucleolar proteins but are impoverished for rRNA
- Evolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation
- A gene expression map of the larval Xenopus laevis head reveals developmental changes underlying the evolution of new skeletal elements
- Embryonic development of the nervous system in the planarian Schmidtea polychroa
- Pentimento: Neural Crest and the origin of mesectoderm
- The many faces of cell adhesion during Drosophila muscle development
- Lizard tail regeneration: regulation of two distinct cartilage regions by Indian hedgehog
- Loss of cftr function leads to pancreatic destruction in larval zebrafish
- Hanging on for the ride: Adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and disease
- The boule gene is essential for spermatogenesis of haploid insect male
- The cochlear sensory epithelium derives from Wnt responsive cells in the dorsomedial otic cup
- Diverse ETS transcription factors mediate FGF signaling in the Ciona anterior neural plate
- Tie1 is required for lymphatic valve and collecting vessel development
- Insulin-independent role of adiponectin receptor signaling in Drosophila germline stem cell maintenance
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- From equator to pole: splitting chromosomes in mitosis and meiosis [Reviews]
- A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation [Research Communications]
- The transcription factor Nerfin-1 prevents reversion of neurons into neural stem cells [Research Papers]
- Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2 [Research Papers]
- Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth [Research Papers]
- ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis [Research Papers]
- FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation [Research Papers]
- Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination [Research Papers]
- Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly [Research Papers]
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- A Role for the Ancient SNARE Syntaxin 17 in Regulating Mitochondrial Division
- Endocytosis of Hedgehog through Dispatched Regulates Long-Range Signaling
- Actin-Delimited Adhesion-Independent Clustering of E-Cadherin Forms the Nanoscale Building Blocks of Adherens Junctions
- Interkinetic Nuclear Migration Is Centrosome Independent and Ensures Apical Cell Division to Maintain Tissue Integrity
- Salvador-Warts-Hippo Pathway in a Developmental Checkpoint Monitoring Helix-Loop-Helix Proteins
- Phosphorylation of Cohesin Rec11/SA3 by Casein Kinase 1 Promotes Homologous Recombination by Assembling the Meiotic Chromosome Axis
- Hypo- or Hyper-Hippo: A Balancing Act with bHLH Transcription Factors
- Enhancer Trafficking: Free Throws and Three-Pointers
- Sequential Contraction and Exchange of Apical Junctions Drives Zippering and Neural Tube Closure in a Simple Chordate
- Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins
- Functional Reprogramming of Polyploidization in Megakaryocytes
- The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression
- Casein Kinase 1 Promotes Initiation of Clathrin-Mediated Endocytosis
