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The Node is a place to share news about and with the developmental biology community around the world. If this is your first time on the site, check out this introduction to the Node. You can also find out more about us, and sign up to contribute.
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Exhausted but satisfied
Posted by Kim Cooper on March 31st, 2012
The breakfast bell rang early this morning, so I’ve only just gotten my shower this evening which is a good thing since I was filthy and covered in sand. We headed back to the spot where we set traps last night, and lo and behold I think we only lost one. And I could be […]
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Stairway to Learning
Posted by Smrithi on March 30th, 2012
When I stepped into the Institute of Genetics, Mainz, I stepped into the world of neural development - I was like Aladdin in the Cave of Wonders! It was all so new to me - so exciting, and so much to learn! Prof. Gerhard Technau’s group worked on different aspects of Drosophila neural development - […]
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This Month on the Node – March 2012
Posted by Eva Amsen on March 30th, 2012
Money appears to have been the main topic of conversation this month. In the past few weeks, we’ve had a glimpse into the status of science funding in countries around the world. Paul O’Neill shared some news about the current funding situation in Japan, where government advisors recommended amalgamation of the main science bodies to […]
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Wildlife abounds, but jerboas?
Posted by Kim Cooper on March 29th, 2012
This morning after a breakfast of fermented tofu on steamed buns, boiled peanut and rice soup, spicy strands of seaweed, and a plate of mixed onion, peppers, and tomato in vinegar, we headed off in the jeep in search of the right kind of desert for jerboas. I knew one of the places where we’d […]
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Banners
Posted by the Node on March 28th, 2012
If you’ve recently visited our Facebook page, you may have already seen them, but we have some new banners - of both the physical and digital kind. First of all, we have a new banner to take to conferences. If you’re going to some of the conferences where The Company of Biologists has a stand, […]
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Nihao from Xinjiang
Posted by Kim Cooper on March 28th, 2012
I have sprung up again in China. It’s time for another field collection of jerboa embryos in far northwestern China (Xinjiang), and since this is the reason Eva invited me to contribute to the Node, I figure it is finally time for me to oblige. The last couple of days were eventful. Friday morning I […]
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Post-doctoral position in Drosophila hematopoiesis: deciphering the niche function
Posted by vincent on March 20th, 2012
A 3 years post-doctoral position is immediately available in the laboratory of Michèle Crozatier and Alain Vincent, at the Centre de Biologie du Développement CNRS/Toulouse University, France. One main topic of the lab concerns Drosophila hematopoiesis, the hematopoietic niche and the plasticity of cell fates in the lymph gland (http://www-cbd.ups-tlse.fr/spip.php?rubrique53). The candidate will further explore […]
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In Development this week (Vol. 139, Issue 8)
Posted by Seema Grewal on March 20th, 2012
Here are the highlights from the current issue of Development: Chewing the Fat over PCP and growth The Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP) but also inhibits the overgrowth of imaginal discs by activating the Hippo pathway. The intracellular domain (ICD) mediates much of Ft activity, but are its PCP and Hippo […]
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FlyBase 2012 User Survey
Posted by Josh Goodman on March 20th, 2012
Dear Colleagues, FlyBase has begun to plan for the competitive renewal of FlyBase funding, which will be submitted to NIH in several months. EXTENSIVE INPUT from the community of FlyBase users is invaluable in two ways. (1) It is a crucial source of input to help us determine our priorities for the next five year period. (2) The […]
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An interview with José Xavier Neto
Posted by Eva Amsen on March 20th, 2012
(This interview originally appeared in Development.) The Latin American Society for Developmental Biology (LASDB) is getting ready for their Sixth International Meeting, which will be held in Montevideo, Uruguay, from April 26th to 29th, 2012. To find out more about the society, and about developmental biology in Latin America, we talked to LASDB president José […]
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- Spine-tingling new role for Sall4 [IN THIS ISSUE]
- Ageing thymus out-FOXed [IN THIS ISSUE]
- Muscling in on stem cell hierarchy [IN THIS ISSUE]
- Nucleolus precursor body makeover [IN THIS ISSUE]
- Moss stem cells do it differently [IN THIS ISSUE]
- Change of heart for RA signalling [IN THIS ISSUE]
- The evolution and conservation of left-right patterning mechanisms [HYPOTHESIS]
- The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease [REVIEW]
- Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus [RESEARCH ARTICLES]
- The maternal nucleolus plays a key role in centromere satellite maintenance during the oocyte to embryo transition [RESEARCH ARTICLES]
- The egg membrane microdomain-associated uroplakin III-Src system becomes functional during oocyte maturation and is required for bidirectional gamete signaling at fertilization in Xenopus laevis [RESEARCH ARTICLES]
- Development of five digits is controlled by a bipartite long-range cis-regulator [RESEARCH ARTICLES]
- Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord [RESEARCH ARTICLES]
- Type I TARPs promote dendritic growth of early postnatal neocortical pyramidal cells in organotypic cultures [RESEARCH ARTICLES]
- Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination [RESEARCH ARTICLES]
- Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis [RESEARCH ARTICLES]
- A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication [RESEARCH ARTICLES]
- Pulses of Notch activation synchronise oscillating somite cells and entrain the zebrafish segmentation clock [RESEARCH ARTICLES]
- Genetically encoded molecular probes to visualize and perturb signaling dynamics in living biological systems [Articles of interest in other COB journals]
- Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours [Articles of interest in other COB journals]
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- Editorial Board
- Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers
- Hipk promotes photoreceptor differentiation through the repression of Twin of eyeless and Eyeless expression
- Unc45b is essential for early myofibrillogenesis and costamere formation in zebrafish
- Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells
- Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear
- Mesodermal Nkx2.5 is necessary and sufficient for early second heart field development
- Maternal bias and escape from X chromosome imprinting in the midgestation mouse placenta
- Editorial Board
- Do the BEAF insulator proteins regulate genes involved in cell polarity and neoplastic growth?
- Lhx1 is required in Müllerian duct epithelium for uterine development
- A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans
- Cleavage of the Drosophila screw prodomain is critical for a dynamic BMP morphogen gradient in embryogenesis
- Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads
- CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways
- The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis
- Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones
- Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages
- Editorial Board
- Development and evolution of vertebrate cranial placodes
- Setting appropriate boundaries: Fate, patterning and competence at the neural plate border
- Establishing the pre-placodal region and breaking it into placodes with distinct identities
- Neural crest and placode interaction during the development of the cranial sensory system
- Signaling mechanisms controlling cranial placode neurogenesis and delamination
- Sensational placodes: Neurogenesis in the otic and olfactory systems
- The development of lateral line placodes: Taking a broader view
- The evolutionary history of vertebrate cranial placodes – I: Cell type evolution
- The evolutionary history of vertebrate cranial placodes II. Evolution of ectodermal patterning
- Resident progenitors, not exogenous migratory cells, generate the majority of visceral mesothelium in organogenesis
- Editorial Board
- Impact
- Why you should publish your papers in Developmental Biology
- SDB 2014 Meeting Announcement
- Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death
- Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis
- Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis
- Epigenetic regulation of oogenesis and germ stem cell maintenance by the Drosophila histone methyltransferase Eggless/dSetDB1
- Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development
- The bristle patterning genes hairy and extramacrochaetae regulate the development of structures required for flight in Diptera
- Retraction notice to “The human placenta is a hematopoietic organ during the embryonic and fetal periods of development” [Dev. Biol. 327 (2009) 24–33]
- Ecdysone differentially regulates metamorphic timing relative to 20-hydroxyecdysone by antagonizing juvenile Hormone in Drosophila melanogaster
- Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney
- Peroxisomal membrane channel Pxmp2 in the mammary fat pad is essential for stromal lipid homeostasis and for development of mammary gland epithelium in mice
- Cell signaling during development of Dictyostelium
- Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear
- Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning
- The PAF1 complex is involved in embryonic epidermal morphogenesis in Caenorhabditis elegans
- Neuroblast lineage identification and lineage-specific Hox gene action during postembryonic development of the subesophageal ganglion in the Drosophila central brain
- miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells
- Editorial Board
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- Dystrophic muscle environment induces changes in cell plasticity [Perspectives]
- DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos [Reviews]
- The diabetes gene Hhex maintains {delta}-cell differentiation and islet function [Research Communications]
- Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e [Research Communications]
- HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles [Research Papers]
- miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGF{beta} and Wnt signaling [Research Papers]
- ATR checkpoint kinase and CRL1{beta}TRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks [Research Papers]
- Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression [Research Papers]
- Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress [Research Papers]
- Root growth is modulated by differential hormonal sensitivity in neighboring cells [Research Papers]
- Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin [Errata]
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