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The Node is a place to share news about and with the developmental biology community around the world. If this is your first time on the site, check out this introduction to the Node. You can also find out more about us, and sign up to contribute.
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Exhausted but satisfied
Posted by Kim Cooper on March 31st, 2012
The breakfast bell rang early this morning, so I’ve only just gotten my shower this evening which is a good thing since I was filthy and covered in sand. We headed back to the spot where we set traps last night, and lo and behold I think we only lost one. And I could be […]
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Stairway to Learning
Posted by Smrithi on March 30th, 2012
When I stepped into the Institute of Genetics, Mainz, I stepped into the world of neural development - I was like Aladdin in the Cave of Wonders! It was all so new to me - so exciting, and so much to learn! Prof. Gerhard Technau’s group worked on different aspects of Drosophila neural development - […]
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This Month on the Node – March 2012
Posted by Eva Amsen on March 30th, 2012
Money appears to have been the main topic of conversation this month. In the past few weeks, we’ve had a glimpse into the status of science funding in countries around the world. Paul O’Neill shared some news about the current funding situation in Japan, where government advisors recommended amalgamation of the main science bodies to […]
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Wildlife abounds, but jerboas?
Posted by Kim Cooper on March 29th, 2012
This morning after a breakfast of fermented tofu on steamed buns, boiled peanut and rice soup, spicy strands of seaweed, and a plate of mixed onion, peppers, and tomato in vinegar, we headed off in the jeep in search of the right kind of desert for jerboas. I knew one of the places where we’d […]
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Banners
Posted by the Node on March 28th, 2012
If you’ve recently visited our Facebook page, you may have already seen them, but we have some new banners - of both the physical and digital kind. First of all, we have a new banner to take to conferences. If you’re going to some of the conferences where The Company of Biologists has a stand, […]
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Nihao from Xinjiang
Posted by Kim Cooper on March 28th, 2012
I have sprung up again in China. It’s time for another field collection of jerboa embryos in far northwestern China (Xinjiang), and since this is the reason Eva invited me to contribute to the Node, I figure it is finally time for me to oblige. The last couple of days were eventful. Friday morning I […]
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Post-doctoral position in Drosophila hematopoiesis: deciphering the niche function
Posted by vincent on March 20th, 2012
A 3 years post-doctoral position is immediately available in the laboratory of Michèle Crozatier and Alain Vincent, at the Centre de Biologie du Développement CNRS/Toulouse University, France. One main topic of the lab concerns Drosophila hematopoiesis, the hematopoietic niche and the plasticity of cell fates in the lymph gland (http://www-cbd.ups-tlse.fr/spip.php?rubrique53). The candidate will further explore […]
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In Development this week (Vol. 139, Issue 8)
Posted by Seema Grewal on March 20th, 2012
Here are the highlights from the current issue of Development: Chewing the Fat over PCP and growth The Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP) but also inhibits the overgrowth of imaginal discs by activating the Hippo pathway. The intracellular domain (ICD) mediates much of Ft activity, but are its PCP and Hippo […]
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FlyBase 2012 User Survey
Posted by Josh Goodman on March 20th, 2012
Dear Colleagues, FlyBase has begun to plan for the competitive renewal of FlyBase funding, which will be submitted to NIH in several months. EXTENSIVE INPUT from the community of FlyBase users is invaluable in two ways. (1) It is a crucial source of input to help us determine our priorities for the next five year period. (2) The […]
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An interview with José Xavier Neto
Posted by Eva Amsen on March 20th, 2012
(This interview originally appeared in Development.) The Latin American Society for Developmental Biology (LASDB) is getting ready for their Sixth International Meeting, which will be held in Montevideo, Uruguay, from April 26th to 29th, 2012. To find out more about the society, and about developmental biology in Latin America, we talked to LASDB president José […]
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- talpid2: a mystery finally solved [IN THIS ISSUE]
- Starvation MESses up the egg [IN THIS ISSUE]
- A taste for something new [IN THIS ISSUE]
- Cell heterogeneity and multilineage priming in the kidney [IN THIS ISSUE]
- The POU-er of gene nomenclature [SPOTLIGHT]
- The dynamics of plant plasma membrane proteins: PINs and beyond [REVIEW]
- Retinoic acid controls body axis extension by directly repressing Fgf8 transcription [RESEARCH REPORTS]
- The F-box protein Slmb restricts the activity of aPKC to polarize epithelial cells [RESEARCH REPORTS]
- Slmb antagonises the aPKC/Par-6 complex to control oocyte and epithelial polarity [RESEARCH ARTICLES]
- Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium [RESEARCH ARTICLES]
- The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2 [RESEARCH ARTICLES]
- Starvation induces FoxO-dependent mitotic-to-endocycle switch pausing during Drosophila oogenesis [RESEARCH ARTICLES]
- A crucial role for polysialic acid in developmental interneuron migration and the establishment of interneuron densities in the mouse prefrontal cortex [RESEARCH ARTICLES]
- The origin and loss of periodic patterning in the turtle shell [RESEARCH ARTICLES]
- Congenital heart disease protein 5 associates with CASZ1 to maintain myocardial tissue integrity [RESEARCH ARTICLES]
- Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis [RESEARCH ARTICLES]
- Simultaneous rather than ordered cleavage of two sites within the BMP4 prodomain leads to loss of ligand in mice [RESEARCH ARTICLES]
- Loss of focal adhesions in glia disrupts both glial and photoreceptor axon migration in the Drosophila visual system [RESEARCH ARTICLES]
- Islet is a key determinant of ascidian palp morphogenesis [RESEARCH ARTICLES]
- NF-kB controls axonal regeneration and degeneration through cell-specific balance of RelA and p50 in the adult CNS [Articles of interest in other COB journals]
- The conserved transmembrane proteoglycan Perdido/Kon-tiki is essential for myofibrillogenesis and sarcomeric structure in Drosophila [Articles of interest in other COB journals]
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- Editorial Board
- The basal position of nuclei is one pre-requisite for asymmetric cell divisions in the early mouse embryo
- The fat-like cadherin CDH-4 acts cell-non-autonomously in anterior–posterior neuroblast migration
- Staufen targets coracle mRNA to Drosophila neuromuscular junctions and regulates GluRIIA synaptic accumulation and bouton number
- Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton
- Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast
- Transcriptional regulation of Drosophila gonad formation
- Direct functional consequences of ZRS enhancer mutation combine with secondary long range SHH signalling effects to cause preaxial polydactyly
- Cdc42 is required in a genetically distinct subset of cardiac cells during Drosophila dorsal vessel closure
- Setdb2 controls convergence and extension movements during zebrafish gastrulation by transcriptional regulation of dvr1
- Functional characterization of Prickle2 and BBS7 identify overlapping phenotypes yet distinct mechanisms
- Daughterless homodimer synergizes with Eyeless to induce Atonal expression and retinal neuron differentiation
- SUMV-1 antagonizes the activity of synthetic multivulva genes in Caenorhabditis elegans
- GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development
- Migratory neural crest cell αN-catenin impacts chick trigeminal ganglia formation
- Specific pattern of cell cycle during limb fetal myogenesis
- Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development
- Nemo promotes Notch-mediated lateral inhibition downstream of proneural factors
- Elf5 counteracts precocious trophoblast differentiation by maintaining Sox2 and 3 and inhibiting Hand1 expression
- Gtpbp2 is required for BMP signaling and mesoderm patterning in Xenopus embryos
- Hectd1 is required for development of the junctional zone of the placenta
- Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation
- miR-203 regulates progenitor cell proliferation during adult zebrafish retina regeneration
- Dynamics of F-actin prefigure the structure of butterfly wing scales
- Germ cells of the centipede Strigamia maritima are specified early in embryonic development
- The expansion of body coloration involves coordinated evolution in cis and trans within the pigmentation regulatory network of Drosophila prostipennis
- Emergence of tissue sensitivity to Hox protein levels underlies the evolution of an adaptive morphological trait
- Long bone development requires a threshold of Hox function
- Enhancer diversity and the control of a simple pattern of Drosophila CNS midline cell expression
- A distant downstream enhancer directs essential expression of Tbx18 in urogenital tissues
- Editorial Board
- Development of the lateral line canal system through a bone remodeling process in zebrafish
- NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling
- Protein kinase CK2 both promotes robust proliferation and inhibits the proliferative fate in the C. elegans germ line
- TAF4b promotes mouse primordial follicle assembly and oocyte survival
- Regulation of broad by the Notch pathway affects timing of follicle cell development
- Cited2 is required in trophoblasts for correct placental capillary patterning
- Polyspermy block in jellyfish eggs: Collaborative controls by Ca2+ and MAPK
- The role of Bro1- domain-containing protein Myopic in endosomal trafficking of Wnt/Wingless
- Phosphorylation of CDK2 at threonine 160 regulates meiotic pachytene and diplotene progression in mice
- Transcriptional co-regulation of evolutionarily conserved microRNA/cone opsin gene pairs: Implications for photoreceptor subtype specification
- Corrigendum to “prdm12b Specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements” [Dev. Biol. 390 (2014) 247–260]
- Abnormal cerebellar development and Purkinje cell Defects in Lgl1-Pax2 conditional knockout mice
- Specification of the mouse cardiac conduction system in the absence of Endothelin signaling
- Identification of genes driving lineage divergence from single-cell gene expression data in C. elegans
- The dystroglycan: Nestled in an adhesome during embryonic development
- Developmental regulation of glial cell phagocytic function during drosophila embryogenesis
- Editorial Board
- Resident progenitors, not exogenous migratory cells, generate the majority of visceral mesothelium in organogenesis
- A gene expression atlas of early craniofacial development
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- Wnt some lose some: transcriptional governance of stem cells by Wnt/{beta}-catenin signaling [Reviews]
- Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling [Reviews]
- Two waves of de novo methylation during mouse germ cell development [Research Communications]
- TRF2, but not TBP, mediates the transcription of ribosomal protein genes [Research Communications]
- Healing for destruction: tRNA intron degradation in yeast is a two-step cytoplasmic process catalyzed by tRNA ligase Rlg1 and 5'-to-3' exonuclease Xrn1 [Research Communications]
- The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages [Research Papers]
- Lineage of origin in rhabdomyosarcoma informs pharmacological response [Research Papers]
- Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions [Research Papers]
- A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication [Research Papers]
- MicL, a new {sigma}E-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein [Research Papers]
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- Spatial Regionalization and Heterochrony in the Formation of Adult Pallial Neural Stem Cells
- SAS-6 Assembly Templated by the Lumen of Cartwheel-less Centrioles Precedes Centriole Duplication
- High-Resolution Mapping of Chromatin Packaging in Mouse Embryonic Stem Cells and Sperm
- Uniformity of Nucleosome Preservation Pattern in Mammalian Sperm and Its Connection to Repetitive DNA Elements
- Regulation of Plant Stem Cell Quiescence by a Brassinosteroid Signaling Module
- Multiple Mechanisms Modulate Distinct Cellular Susceptibilities toward Apoptosis in the Developing Eye
- Independent Genomic Control of Neuronal Number across Retinal Cell Types
- Distinct Chemokine Signaling Regulates Integrin Ligand Specificity to Dictate Tissue-Specific Lymphocyte Homing
- Live Free or Die: Cell-Cell Adhesion Regulates Sensitivity to Trail-Induced Apoptosis
- The LC3 Acts Downstream of GABARAP to Degrade Autophagosomes by Interacting with the HOPS Subunit VPS39
- Finding a Common Path: Predicting Gene Function using Inferred Evolutionary Trees
- With NuRD, HDACs Go “Nerdy”
- Paternal Nucleosomes: Are They Retained in Developmental Promoters or Gene Deserts?
- Mitochondria Are Clamped to Vacuoles for Lipid Transport
- A Dynamic Interface between Vacuoles and Mitochondria in Yeast
- Cellular Metabolism Regulates Contact Sites between Vacuoles and Mitochondria
- Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway
