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The Node is a place to share news about and with the developmental biology community around the world. If this is your first time on the site, check out this introduction to the Node. You can also find out more about us, and sign up to contribute.
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This month on the Node – January 2013
Posted by the Node on January 31st, 2013
Let’s start this monthly summary with two fantastic posts that were left out of last month’s roundup due to the holiday period (and scheduled posts). Idoia Quintana studies shark brain development in Spain, and travelled to Scotland recently to learn how to work with mouse brains, so she could do some cross-species comparison. “At the […]
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Post-doc position in evolution and development in Paris
Posted by MichelVervoort on January 31st, 2013
A two-year post-doctoral positionis available in the group of Guillaume Balavoine and Michel Vervoort (http://www.ijm.fr/en/ijm/research/research-groups/metazoaires/) at the Institut Jacques Monod (IJM) in Paris (France). The IJM is a leading French biological research institute, comprising about 25 interactive research groups and high-quality technological facilities, including a cutting-edge imaging platform. The primary research focus of the group is to […]
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Vote for a Development cover – Woods Hole 2012 class round 1
Posted by the Node on January 30th, 2013
Each year, students of the Woods Hole Embryology course produce some amazing images. Last year, readers of the Node selected four images from the 2011 course to appear on the cover of Development. Now it’s time to do the same with the images from the 2012 course. Here’s the first batch of […]
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In Development this week (Vol. 140, Issue 4)
Posted by Seema Grewal on January 29th, 2013
Here are the highlights from the current issue of Development: Pancreatic injury unlocks cell potential Identifying methods by which pancreatic β-cells can be produced is of major therapeutic importance. Whether there are adult pancreatic cells with the potential to make new β-cells is a matter of much debate. During embryonic development, the transcription factor […]
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Stem cells at school, plus new fact sheets on EuroStemCell
Posted by Emma Kemp on January 29th, 2013
Happy 2013 everyone! I hope you’re all settling into the year nicely.We sent out our EuroStemCell January newsletter last week and I thought some of you might be interested in our latest schools activities and fact sheets on stem cell research. Highlights this month include a new lesson for 12-14 year olds on Stem cell […]
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Woods Hole course application deadline extended
Posted by the Node on January 28th, 2013
The Woods Hole image voting posts are some of the most popular posts on the Node (and yes, there will be a new one up VERY soon!). These images are all made by students of the Woods Hole Embryology course, and you still have a chance to be part of the 2013 class! The application […]
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Microinjection of preimplantation mouse embryos
Posted by svanderweide on January 28th, 2013
Hello, my name is Stephanie and I’m a graduate student in Dr. Amy Ralston’s lab at the University of California Santa Cruz. I just returned from a trip to Dr. Yojiro Yamanaka’s lab at McGill University in Montreal, Quebec. This trip was funded by the Development Travelling Fellowship from Company of Biologists. I highly recommend checking […]
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PhD opportunity available in Dundee
Posted by Marios on January 17th, 2013
O-GlcNAc signalling during embryonic stem cell differentiation My lab is studying the signalling mechanisms governing the onset of differentiation of pluripotent embryonic stem (ES) cells. Work from this and other labs (e.g. 1, 2) has revealed a critical role for autocrine FGF signalling and consequent sustained phosphorylation of the kinase Erk during the differentiation process. […]
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PhD position in the UK for a Developmental Geneticist
Posted by Andre on January 16th, 2013
PhD project title: Non-genetic mechanisms of inheritance influenced by the maternal environment Project description: In the last few decades, it has been becoming increasingly clear that organisms can express phenotypes that are inherited in a non-Mendelian fashion. Studies in humans, for example, show that grandfathers who experienced dramatic diet fluctuations as children influenced the incidence […]
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Early mouse development seen in real time
Posted by Heather Ray on January 15th, 2013
Developmental biologists have long relied on the power of observation to understand how embryos develop. In addition, pharmacologic and genetic manipulation of embryos gives us clues as to the mechanisms involved in proper developmental processes. The ability to combine embryo manipulation with observation of embryonic development in real time has been possible for quite some […]
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- Spine-tingling new role for Sall4 [IN THIS ISSUE]
- Ageing thymus out-FOXed [IN THIS ISSUE]
- Muscling in on stem cell hierarchy [IN THIS ISSUE]
- Nucleolus precursor body makeover [IN THIS ISSUE]
- Moss stem cells do it differently [IN THIS ISSUE]
- Change of heart for RA signalling [IN THIS ISSUE]
- The evolution and conservation of left-right patterning mechanisms [HYPOTHESIS]
- The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease [REVIEW]
- Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus [RESEARCH ARTICLES]
- The maternal nucleolus plays a key role in centromere satellite maintenance during the oocyte to embryo transition [RESEARCH ARTICLES]
- The egg membrane microdomain-associated uroplakin III-Src system becomes functional during oocyte maturation and is required for bidirectional gamete signaling at fertilization in Xenopus laevis [RESEARCH ARTICLES]
- Development of five digits is controlled by a bipartite long-range cis-regulator [RESEARCH ARTICLES]
- Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord [RESEARCH ARTICLES]
- Type I TARPs promote dendritic growth of early postnatal neocortical pyramidal cells in organotypic cultures [RESEARCH ARTICLES]
- Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination [RESEARCH ARTICLES]
- Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis [RESEARCH ARTICLES]
- A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication [RESEARCH ARTICLES]
- Pulses of Notch activation synchronise oscillating somite cells and entrain the zebrafish segmentation clock [RESEARCH ARTICLES]
- Genetically encoded molecular probes to visualize and perturb signaling dynamics in living biological systems [Articles of interest in other COB journals]
- Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours [Articles of interest in other COB journals]
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- Editorial Board
- Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers
- Hipk promotes photoreceptor differentiation through the repression of Twin of eyeless and Eyeless expression
- Unc45b is essential for early myofibrillogenesis and costamere formation in zebrafish
- Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells
- Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear
- Mesodermal Nkx2.5 is necessary and sufficient for early second heart field development
- Maternal bias and escape from X chromosome imprinting in the midgestation mouse placenta
- Editorial Board
- Do the BEAF insulator proteins regulate genes involved in cell polarity and neoplastic growth?
- Lhx1 is required in Müllerian duct epithelium for uterine development
- A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans
- Cleavage of the Drosophila screw prodomain is critical for a dynamic BMP morphogen gradient in embryogenesis
- Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads
- CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways
- The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis
- Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones
- Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages
- Editorial Board
- Development and evolution of vertebrate cranial placodes
- Setting appropriate boundaries: Fate, patterning and competence at the neural plate border
- Establishing the pre-placodal region and breaking it into placodes with distinct identities
- Neural crest and placode interaction during the development of the cranial sensory system
- Signaling mechanisms controlling cranial placode neurogenesis and delamination
- Sensational placodes: Neurogenesis in the otic and olfactory systems
- The development of lateral line placodes: Taking a broader view
- The evolutionary history of vertebrate cranial placodes – I: Cell type evolution
- The evolutionary history of vertebrate cranial placodes II. Evolution of ectodermal patterning
- Resident progenitors, not exogenous migratory cells, generate the majority of visceral mesothelium in organogenesis
- Editorial Board
- Impact
- Why you should publish your papers in Developmental Biology
- SDB 2014 Meeting Announcement
- Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death
- Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis
- Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis
- Epigenetic regulation of oogenesis and germ stem cell maintenance by the Drosophila histone methyltransferase Eggless/dSetDB1
- Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development
- The bristle patterning genes hairy and extramacrochaetae regulate the development of structures required for flight in Diptera
- Retraction notice to “The human placenta is a hematopoietic organ during the embryonic and fetal periods of development” [Dev. Biol. 327 (2009) 24–33]
- Ecdysone differentially regulates metamorphic timing relative to 20-hydroxyecdysone by antagonizing juvenile Hormone in Drosophila melanogaster
- Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney
- Peroxisomal membrane channel Pxmp2 in the mammary fat pad is essential for stromal lipid homeostasis and for development of mammary gland epithelium in mice
- Cell signaling during development of Dictyostelium
- Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear
- Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning
- The PAF1 complex is involved in embryonic epidermal morphogenesis in Caenorhabditis elegans
- Neuroblast lineage identification and lineage-specific Hox gene action during postembryonic development of the subesophageal ganglion in the Drosophila central brain
- miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells
- Editorial Board
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- Dystrophic muscle environment induces changes in cell plasticity [Perspectives]
- DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos [Reviews]
- The diabetes gene Hhex maintains {delta}-cell differentiation and islet function [Research Communications]
- Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e [Research Communications]
- HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles [Research Papers]
- miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGF{beta} and Wnt signaling [Research Papers]
- ATR checkpoint kinase and CRL1{beta}TRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks [Research Papers]
- Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression [Research Papers]
- Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress [Research Papers]
- Root growth is modulated by differential hormonal sensitivity in neighboring cells [Research Papers]
- Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin [Errata]
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