the community site for and by developmental biologists

Confess your lab sins

Posted by on July 31st, 2013

Remember the hashtag #overlyhonestmethods that was trending on Twitter a few months ago? Well, the new science hashtag to follow is #sciconfessions : a collection of the lab sins that you never told anyone (and definitely not to your Health & Safety officer!). We storified our favourites, but why don’t join the discussion on Twitter[…]

Beautiful stem cells on eurostemcell.org

Posted by on July 31st, 2013

Hi everyone! I hope you’re enjoying the sun. We’ve just sent out our July newsletter over at EuroStemCell and we’ve got quite a bit of news that I thought my interest members of The Node:         Christele Gonneau joins us as a new image blogger and you can expect to see her[…]

Remembrance of Brains Past

Posted by on July 30th, 2013

What would happen to your memories and personality if, after decades of adult life, some portion of your brain was replaced with the progeny of fresh stem cells (as might happen in a treatment for degenerative brain disease)? Given the fascinating but poorly-understood examples of memory in aneural systems such as plants, ciliates, etc. (Eisenstein,[…]

In Development this week (Vol. 140, Issue 16)

Posted by on July 30th, 2013

Here are the highlights form the current issue of Development:   Nf2 regulates neural progenitor proliferation Mutation of neurofibromatosis 2 (NF2) results in nervous system tumours. Molecularly, Nf2 has diverse functions, regulating cell-cell junction formation and various signalling pathways, including the Hippo-Yap pathway. However, the roles of Nf2 in the nervous system, and how its[…]

Synchronicity: Laser-targeted ablation timed with zebrafish embryonic heart cycle

Posted by on July 29th, 2013

Matrone G, Taylor JM, Wilson KS, Baily J, Love GD, Girkin JM, Mullins JJ, Tucker CS, Denvir MA. Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair. Int J Cardiol. 2013 Jul 17. doi:pii: S0167-5273(13)01117-0. 10.1016/j.ijcard.2013.06.063. [Epub ahead of print] PubMed PMID: 23871347 (Open Access Article) In a study[…]

Sex-reversal in adult fish

Posted by on July 27th, 2013

Dranow DB, Tucker RP and Draper BW. Germ cells are required to maintain a stable sexual phenotype in adult zebrafish. Developmental Biology 376: 43-50. Adult sex-reversal  –  the change of primary sex (gonadal sex) and secondary sex characteristics and  to another sex during adulthood, occurs in many fish species and is triggered by social or[…]

Alcohol, genes, and fish faces

Posted by on July 26th, 2013

Like me, when you were a kid many of you probably puckered your lips and placed your hands on the side of you neck to make believe that you were a fish. At the time, you were probably just being silly and didn’t realize how similar you actually are to a fish. The zebrafish is[…]

Wave at the frogs – they’re waving at you

Posted by on July 26th, 2013

  Perhaps, like me, you’ve been microinjecting Xenopus embryos for so long that you start seeing strange things – maybe that they’re waving at you.  But perhaps that’s not so crazy as it sounds.  In a letter to Nature this week (you can also view this talk), Jeremy Chang and James Ferrell Jr. from Stanford discuss the evidence[…]

The 8th European Zebrafish Meeting

Posted by on July 25th, 2013

By Leonardo Valdivia and Joaquín Letelier Here is a report about sessions performed during the 8th European Zebrafish meeting held in Barcelona. The post is divided in different topics to make it easy to read.  Of course we did not cover all sessions and tried to focus on talks related to developmental biology, but we[…]

The Fly Room Project

Posted by on July 24th, 2013

The field of modern genetics owes a lot to the pioneering work of Thomas Hunt Morgan on the little fruit fly. A great part of his work was conducted in a small, busy fly room at Columbia University, famous not only for the great science that was done there but also for its democratic social[…]