the community site for and by developmental biologists

Woods Hole images round 4- the winning movie

Posted by on September 30th, 2013

This year’s last Woods Hole competition had an exciting development- instead of choosing from 4 images, we asked the Node readers to choose from 4 stunning movies. It was probably hard to choose who to vote for, but in the end the beautiful movie of the ascidian metamorphosis was the big winner. The following collection[…]

Stem Cells: An Insider’s Guide – the new book by Paul Knoepfler

Posted by on September 30th, 2013

I recently had the pleasure of interviewing Associate Professor and dedicated stem cell blogger Dr. Paul Knoepfler about his upcoming book “Stem Cells: An Insider’s Guide”. The book covers everything from defining stem cells and their clinical applications to stem cell regulation and even some stem cell urban legends. Here, Paul chats about his book,[…]

And in the beginning was histone 1

Posted by on September 30th, 2013

A team at IRB Barcelona identifies an essential protein for embryonic viability during the first cell divisions in the fly Drosophila. This protein, called dBigH1, which is a variant of histone 1, could also be associated with fertility issues.   A zygote is the first cell of a new individual that comes about as the[…]

Biology Bytes: A Stem Cell-Focused Book for the Public

Posted by on September 22nd, 2013

I recently published a book, called Biology Bytes: Digestible Essays on Stem Cells and Modern Medicine, which is on stem cells and other medical-related topics, and thought it would be of interest to readers at The Node. A large part of the book is just on stem cells — specifically, an entire chapter (74 pages)[…]

Stem cell success is team work!

Posted by on September 17th, 2013

    Stem cell beauty…yes they are so beautiful, they have amazing properties, they bring a lot of hope for future therapies…well, yes they are the stars! However, like in everyday life, “the star” is not the only one to be the key of its own success, success is teamwork! And for stem cells, the[…]

In Development this week (Vol. 140, Issue 19)

Posted by on September 17th, 2013

Here are the highlights from the new issue of Development:   Roadmap for human trophoblast model Correct trophoblast development is essential for placenta function and embryogenesis. In humans, the early stages of this process can only be modelled in vitro using embryonic stem cells (ESCs); however, owing to the failure to identify the stepwise progression[…]

(Developmental) Biology around the internet- September 2013

Posted by on September 16th, 2013

Here is our monthly round-up of some of the interesting content that we spotted around the internet:   News & Research – Nature reported this month that stem cells have been used to generate minibrains in vitro. You can read an excellent article by Ed Yong on this work . – The hilarious 2013 IgNobel Prizes[…]

Proepicardial cells go for a swim: how fluid flows guide epicardial progenitors to the heart

Posted by on September 12th, 2013

The epicardium, the layer of cells covering the myocardium, plays an essential role in heart maturation and formation of the heart valves and coronary vasculature. It derives from the proepicardium (PE), a cluster of cells emerging from the inner lining of the pericardial wall, in which the heart is located. During development, PE cells need[…]

Antibody reporting in developmental biology journals

Posted by on September 12th, 2013

We are trying to encourage scientists and journals to work together to improve reporting of antibody experiments which is often poor. See our comment article; http://f1000research.com/articles/2-153/v2 We would really appreciate any information of which DB journals have existing antibody reporting guidelines (so we can credit them) and encourage editors of journals who do not have[…]

An interview with Alejandro Sánchez Alvarado

Posted by on September 11th, 2013

Alejandro Sánchez Alvarado is an investigator at the Stowers Institute and Howard Hughes Medical Institute, and has worked for many years on regeneration in a little flatworm- the planaria. The Node interviewed Alejandro at the 2013 International Society of Developmental Biology meeting, and asked him about his career, his work on regeneration, and his role[…]