the community site for and by developmental biologists

The people behind the papers – Marina Matsumiya & Ryoichiro Kageyama

Posted by on February 19th, 2018

Vertebrate segmentation involves the periodic formation of somites from the presomitic mesoderm, in a manner controlled by oscillating gene expression (the oscillations of the segmentation clock must be one of the marvels of nature!). While in vivo work has provided a framework for studying the process, many aspects of segmentation dynamics are obscured in the embryo. A new Techniques[…]

Genes activated in metastasis also drive the first stages of tumour growth

Posted by on February 19th, 2018

In spite of the difference between the cell functions responsible for giving rise to a tumour and for the metastasis of this same tumour, studies at IRB Barcelona using the fly Drosophila melanogaster reveal that some genes can drive both phenome na.   In cancer research, there has been a tendency to differentiate between the[…]

Emilia Favuzzi: winner of the 2018 Beddington medal

Posted by on February 17th, 2018

The Beddington Medal is the BSDB’s major commendation to promising young biologists, awarded for the best PhD thesis in Developmental Biology defended in the year previous to the award. Rosa Beddington was one of the greatest talents and inspirational leaders in the field of developmental biology. Rosa made an enormous contribution to the field in[…]

A journey towards uncovering the mechanics of embryonic polarization

Posted by on February 17th, 2018

The key results of our recent paper in Nature Cell Biology   Cell polarization defines the spatial biological specificities in a cell. During the first cell cycle of a C. elegans zygote, its symmetry is broken by local remodeling of the cortical actomyosin network. This leads to a segregation of the dedicated polarity regulators, the PAR[…]

Nominate BSDB committee members,

Posted by on February 16th, 2018

Sear BSDB Members,   I am writing to ask you to consider nominating individuals for membership of the BSDB committee.   Due to committee retirements, three new individuals are needed to serve as ordinary committee members, beginning in October 2018.   Their term of office will be five years and they will be required to (make every[…]

Nominate your Drosophila genes of interest for CRISPR fly stock production

Posted by on February 13th, 2018

The DRSC/TRiP-Functional Genomics Resources is a Drosophila community resource with three main focus areas: (1) cell-based Drosophila cell screening, (2) fly stock production, and (3) bioinformatics. Our TRiP fly stock production platform is taking nominations for production of CRISPR sgRNA fly stocks. Researchers can nominate genes for knockout (TRiP CRIPSR-KO) or activation (TRiP CRISPR-OE), or both.[…]

Updates from DORA – An interview with Stephen Curry

Posted by on February 7th, 2018

The San Francisco Declaration on Research Assessment (DORA) was conceived in 2012 at an ASCB meeting, and has since its launch in 2013 has garnered thousands of signatories from individuals and organisations. Its aim is to improve the way in which the quality of research output is evaluated, with a key recommendation being the elimination of journal-based metrics[…]

How does it Work? My Experience with 3 Different Model Systems

Posted by on February 5th, 2018

For both young and established developmental biologists considering their next career move, choosing a model system with which to answer one’s research questions is a big decision. Of course, the most important thing to consider is whether or not a particular system is compatible with your research goals. But for a young scientist looking to[…]

YEN Conference 2018: Abstract submission and registration is open!

Posted by on February 3rd, 2018

Young Embryologist Network Conference 2018 14th May 2018 The Francis Crick Institute, London, UK   This year we are pleased to announce Professor Wolf Reik as our keynote speaker. His research group, based at the Babraham Institute, investigates the roles of epigenetic gene regulation in mammalian development. We are also honoured to have Dr Susan Cox and Dr[…]