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About: Max_Yun

I carried out my PhD studies at Cambridge University (MRC-Laboratory of Molecular Biology), in the area of DNA repair, focusing on the interplay between different DNA repair pathways and their regulation throughout the cell cycle. During my doctoral studies I became interested in regenerative biology and joined Jeremy Brockes’ lab at UCL. Currently, I am trying to answer several outstanding questions in vertebrate regeneration using the salamander as a model system. In particular, I seek to understand what is the molecular nature of the signals that elicit the reprogramming of differentiated cells, a crucial step for regeneration. I am also interested in how and why the regenerative capacity changes with ageing in different species. My research aims to find explanations to these problems in order to understand why some species can regenerate while others cannot, and to guide strategies for the promotion of regeneration in humans. I am also founder and organiser of the London Tissue Repair and Regeneration Meeting Series (

Posts by Max_Yun:

Cellular Senescence in Regeneration

Posted by on June 28th, 2015

Salamanders are remarkable organisms. Following the amputation or loss of complex structures such as parts of their eyes, hearts and brains, tails -including the spinal cord-, jaws and even full limbs, they are able to set up a regeneration programme which leads to the exact replacement of the missing structure, even as adults. As such,[…]