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About: Seema Grewal

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Reviews Editor at Development
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In Development this week (Vol 145, Issue 1)

Posted by on January 16th, 2018

The first Development issue of the year is now complete! Here are the highlights:   RESEARCH HIGHLIGHTS:   Micro-lenses focus on cataract development Cataracts have many potential risk factors but the molecular mechanisms underlying their development are unclear. Aggregates of lens epithelial cells (LECs) derived from human pluripotent stem cells (hPSCs) are a potentially powerful in[…]

In Development this week (Vol. 144, Issue 24)

Posted by on December 18th, 2017

Here are the highlights from the current issue of Development – the last one of the year! Happy reading…and happy holidays!   Branched actin keeps Nrf2 in check in the skin The Arp2/3 complex is responsible for the assembly of branched actin filaments. Although its cellular functions are well understood, less is known about the[…]

In Development this week (Vol. 144, Issue 22)

Posted by on November 14th, 2017

Here are the highlights form the current issue of Development:   Cross-border control of stem cell behaviour Cell identity and proliferation differs between organs, raising the question of how cells at interorgan boundaries are regulated to maintain organ integrity. On p. 4091, Don Fox and colleagues identify a specialised transition zone at the midgut/hindgut boundary in[…]

In Development this week (Vol. 144, Issue 21)

Posted by on October 31st, 2017

Here are the highlights form the current issue of Development:   Making matrix in the inner ear The tectorial membrane (TM) is an extracellular matrix (ECM) that overlies the organ of Corti in the inner ear and is crucial for our sense of hearing. It is composed of collagen fibrils embedded in a tectorin-based matrix.[…]

In Development this week (Vol. 144, Issue 19)

Posted by on October 3rd, 2017

Here are the highlights from the current issue of Development:   Making a move: EMT holds the key to planarian regeneration During development and wound healing, progenitor cells are required to migrate to different locations before they can differentiate into terminal tissue types. This cell migration often involves epithelial-to-mesenchymal transition (EMT), a process by which[…]

In Development this week (Vol. 144, Issue 18)

Posted by on September 19th, 2017

Here are the highlights from the current issue of Development:   Separating nematode species by spermatogenesis During spermatogenesis, unnecessary organelles and cytoplasmic components are shed from developing sperm in order to streamline them for optimal motility. These components are partitioned into structures known as ‘residual bodies’, which subsequently separate from the sperm and are lost.[…]

In Development this week (Vol. 144, Issue 14)

Posted by on July 18th, 2017

Here are the highlights from the current issue of Development:   Computing branching pattern complexity Bile – a fluid that aids digestion – is transported from the liver to the intestine through the bile duct. Bile reaches the bile duct itself via a complex, highly branched structure called the intrahepatic biliary network. This network spreads[…]

In Development this Week (Vol. 144, Issue 13)

Posted by on July 4th, 2017

Here are the highlights from the current issue of Development:   Heart tube formation: a gut reaction Morphogenesis of the endoderm-derived foregut (FG) is tightly linked to that of the mesoderm-derived heart tube (HT), with both structures arising at approximately the same time and place in the developing embryo. However, the physical forces that create[…]

In Development this week (Vol. 144, Issue 9)

Posted by on May 2nd, 2017

Here are the highlights from the current issue of Development:   SEGGA: new software for analysing cell shape and dynamics Changes in epithelial cell shape and organisation are essential for tissue morphogenesis, regeneration and repair. In recent years, advances in microscopy have made it possible to capture these changes in living animals, but the quantitative[…]

In Development this week (Vol. 144, Issue 8)

Posted by on April 11th, 2017

Here are the highlights from the current issue of Development:   A new niche for human HSCs Human haematopoiesis occurs at various anatomical sites throughout development, including the yolk sac, the aorta-gonad-mesonephros region, the liver, the placenta and the bone marrow. Cells marked by high expression of CD34 and low CD45 – suggestive of possible[…]