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Adventures in Studying Brain Sex Differences

Posted by , on 8 May 2015

by Peg McCarthy and Bridget Nugent The biological phenomenon of hormonally induced sexual differentiation of the brain has been an empirical topic of study for over 50 years1 but much ...
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Three dimensional human lung tissue in a dish

Posted by , on 6 May 2015

Pioneering efforts by others have made enormous strides in our ability to generate human lung tissue from human pluripotent stem cells (hPSCs); however, these efforts have largely focused on deriving ...
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Neuroblastoma may arise from problems with embryonic nerve development

Posted by , on 1 May 2015

Neuroblastoma is a tumour derived from the peripheral nervous system and is the most common cancer diagnosed within the first year of life. Although is a fairly rare disease, it ...
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Towards a mechanistic understanding of branching innovations in plant evolution.

Posted by , on 29 April 2015

Jill Harrison and Yoan Coudert.   The conquest of land by plants was one of the most significant events in our planet’s history, and was underpinned by a series of ...
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In Development this week (Vol. 142, Issue 9)

Posted by , on 28 April 2015

Here are the highlights from the current issue of Development:   The light at the end of the tubule Tubular structures, such as kidney tubules or blood vessels, carry out ...
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Discovery of an unexpected function of a protein linked to neurodegenerative diseases

Posted by , on 28 April 2015

A study done on fruit flies and published in Nature Communications reveals that the protein dDsk2, in addition to degrading proteins, also plays a key role in regulating gene expression. ...
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England, embryos, and axial columns: a Travelling Fellowship connecting Chicago to Cambridge

Posted by , on 21 April 2015

Greetings from Chicago! My name is Kate Criswell and I am a graduate student at the University of Chicago, working with Dr. Mike Coates on axial column evolution and development ...
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In Development this week (Vol. 142, Issue 8)

Posted by , on 7 April 2015

Here are the highlights from the current issue of Development:   Getting to the heart of human epicardial differentiation The epicardium is crucial for heart development and function, and it ...
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Best method to measure force transmission between cells

Posted by , on 6 April 2015

We have been trying to implement FRET in the lab and transfect our cells with mechanical biosensors, but so far we haven’t managed to successfully force our cells to express our ...
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The small beginnings of gastruloids

Posted by , on 1 April 2015

Mouse embryonic stem cells (mESCs) are by definition cells that can self-renew (make identical copies of themselves) and specialize into any cell type of the body. Since their discovery, scientists ...
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