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Travel Grants: To Conferences of Your Choice

Posted by on October 4th, 2018

Antibodies.com is proud to support researchers with travel grants up to £500. The Award: Each quarter, Antibodies.com offers a travel grant up to £500 to help cover the cost of attending a conference. These travel grants are open to PhD candidates, lab managers, and post-docs from academic research institutions across Europe. The grant is intended[…]

English Translation of Classic Paper in Animal Genetics

Posted by on October 4th, 2018

Soon after the rediscovery of Mendel’s laws of inheritance in plants, French scientist Lucien Cuénot published a paper in 1902, reporting his studies of the inheritance of pigmentation in the house mouse. Cuénot’s results showed that Mendel’s laws of inheritance also applied to animals. This is a fundamental paper in the field of genetics. The[…]

The International Mouse Phenotyping Consortium is creating an encyclopaedia of mammalian gene function, from embryo to adult

Posted by on September 28th, 2018

The entire genome of many species has now been sequenced, but the function of the majority of genes still remains unknown. This is where the International Mouse Phenotyping Consortium (IMPC) comes in, with the goal of characterising all 20,000 or so protein-coding mouse genes. To achieve this, genes are systematically inactivated then mice are put[…]

Showing distributions

Posted by on August 6th, 2018

When reading about co-evolution of prey and predators, I stumbled across a cute new plot type: a half boxplot, half dot plot to show data distributions.   Wilson used this plot to simultaneously visualize summaries about their data (center, spread) and the actual data points. This allows us, the audience, to learn a lot about[…]

New embryo phenotype data from the DMDD programme

Posted by on June 15th, 2018

Following our latest data release, the DMDD website (dmdd.org.uk) now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb defects and cysts in Col4a2 knockouts and replication of the major features of Meckel syndrome in B9d2 knockouts. We have begun to add immunohistochemistry image[…]

Venn, Euler, upset: visualize overlaps in datasets

Posted by on May 25th, 2018

Visualizations for comparing datasets is a topic in all my data viz classes. Current solutions for comparing 2,3, 4 and more datasets are diverse and some are controversial. A one-fits-all solution does not exist, but there are well-working solutions, and some that should be avoided. 1-3 datasets Comparing two or three datasets works well in[…]

A better bar

Posted by on April 18th, 2018

After leaving the bar, what are we to do? I propose to move on to a better bar (and I hope that you will not be disappointed when you find out that I’m actually referring to an interval). In a previous blog I advocated the transparent presentation and reporting of data in graphs. It was[…]

A tribute to parrots

Posted by on April 5th, 2018

In a previous blog, I have disgraced parrots by associating them with P-values and discrediting them for their mechanic repetition. Nevertheless, I admire the vivid colours of these multifaceted birds. Here, I want to make it up by dedicating a pseudo-colour look-up table (LUT) to parrots. The images produced by fluorescence microscopy are best displayed[…]

A droso4school CPD event for teachers

Posted by on February 20th, 2018

The droso4schools initiative is an educational outreach programme run by the Manchester Fly Facility, which I had the opportunity to be actively involved in during a month-long placement (see my previous blog). The aim of this programme is to re-introduce the fruit fly Drosophila melanogaster into school and college biology lessons. For this, the droso4schools[…]

Nominate your Drosophila genes of interest for CRISPR fly stock production

Posted by on February 13th, 2018

The DRSC/TRiP-Functional Genomics Resources is a Drosophila community resource with three main focus areas: (1) cell-based Drosophila cell screening, (2) fly stock production, and (3) bioinformatics. Our TRiP fly stock production platform is taking nominations for production of CRISPR sgRNA fly stocks. Researchers can nominate genes for knockout (TRiP CRIPSR-KO) or activation (TRiP CRISPR-OE), or both.[…]