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Lab technicians in Human Pluripotent Stem Cell-based Cell Therapy in Type 1 Diabetes

Posted by , on 19 October 2017

Closing Date: 15 March 2021

The goal of this project is to engineer therapeutically active islet-like aggregates for future cell therapy phase 1 trials in Type 1 Diabetes (T1D)

Job description 
The laboratory technicians will be responsible for the maintenance of the human pluripotent stem cell (hPSC) lab. The work will include expansion of human embryonic and induced pluripotent stem cells into characterized (e.g. marker analysis and karyotyping) hPSC line batches, development of new methods and protocols for hPSC maintenance and differentiation, transfections of hPSCs and basic characterization of hPSCs (undifferentiated and differentiated) by immunohistochemistry, qPCR and FACS.  The laboratory technicians will secure the quality and reproducibility of the hPSCs to be used by scientists in the group. The candidates will work together with a dedicated team of scientists who together will tackle bottle-necks towards implementing the first phase 1 clinical trial in T1D. The working hours are 37 hours per week. The positions are time limited to the end of 2020 with a possibility of extension.
Qualifications 
Highly motivated and ambitious candidates are encouraged to apply. The positions require solid experience with cell culture, including transfection (traditional and virus-based methods) and gene expression is necessary. Experience in hPSC culture, molecular biology and immunohistochemistry is required. Knowledge of cell biology, developmental biology and morphology is an advantage. The work is independent and demands flexibility and accuracy. Further, you must have good interpersonal skills and good command of English.
Terms of salary, work, and employment
The employments are planned to start as soon as possible upon agreement with the chosen candidate. The place of work is at DanStem, University of Copenhagen, Blegdamsvej 3B, Copenhagen. The positions are time limited to the end of 2020 with a possibility of extension.
Terms of appointment and salary are in accordance with the agreement between the Danish Government and HK-STAT (Danish Technician Association). The position will be at the level of salary group 5 with the possibility to negotiate due to qualifications and experiences.
Application 
An application for any of the positions should be submitted electronically by clicking “Apply online” below. The application must include the following documents/attachments:
  1. Motivated letter of application
  2. Curriculum vitae incl. education, experience, previous employments, language skills and other relevant skills
  3. Certified copy of diplomas/degree certificate(s)
  4. Certified copy of transcript of records
  5. Letter of recommendation

In all cases, ability to perform the job will be the primary consideration, and thus we encourage all – regardless of their personal background and status – to apply.  

Application deadline: 15 November 2017 
For further information, please contact Professor Henrik Semb by e-mail semb@sund.ku.dk
Send your application with your CV as well as names and contact details of referees electronically by clicking the ´Apply online´ below. We only accept electronic applications. 

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