the community site for and by developmental biologists

Citing Data

Posted by on January 17th, 2011

I just got back from attending two meetings about academia and the internet – one in person and the second, in true internet style, virtually. Both meetings at one point or another discussed the growing trend toward archiving and citing data itself (on top of citing the papers written based on analysis of the data).[…]

Arrested Development in Plant miRNA Mutants

Posted by on January 11th, 2011

Animals and Plants have hundreds of miRNAs with diverse roles in gene regulation. In humans, each miRNA family can control up to several hundred genes (or 500 to be exact, in humans). A loss of function in one, can lead to array of developmental defects. Similarly in plants, an miRNA mutant can have a variety of phenotypes. However, interestingly, many miRNAs only have one target, which is frequently a transcription factor that in turn, controls many genes itself. It’s really like a house of cards.

Royal Society Stem Cell Meeting talks online

Posted by on January 11th, 2011

The Royal Society has uploaded audio files of almost all the talks of their Discussion Meeting last October: “2010: What Next for Stem Cell Biology?”. Unfortunately there are no slides to look at (as far as I can tell) so some of the more technical talks may be hard to follow, but if you’re already[…]

Open access video protocol: electroporating zebrafish ears

Posted by on January 10th, 2011

Open-access video protocol for electroporating into zebrafish ears

modENCODE

Posted by on January 6th, 2011

The modENCODE project (model organism encyclopedia of DNA elements) is a collaborative effort to identify all sequence-based functional elements of Drosophila and C. elegans. The project has now produced almost a thousand data sets with information about transcription, epigenetics, replication and gene regulation across different developmental stages and multiple cell lines. Just before the holidays,[…]

Intestinal stem cell regeneration

Posted by on January 5th, 2011

Cancer and stem cells are two very loaded biology concepts, and more frequently can be found in the same discussion.  Stem cells within tumors are able to divide and provide the various differentiated cell types that a tumor requires to thrive.  And, identifying how a normal stem cell divides, or stops dividing, can help further[…]

Funding Opportunity for BSDB members travelling to ES cell course

Posted by on January 5th, 2011

Message from the BSDB, reposted with permission. Keep in mind that the funding opportunities are for BSDB members only, and the final deadline is very, very soon. The poster for the course was posted on the Node earlier. We have the unique opportunity to provide UK BSDB members with funded opportunities to attend an intensive[…]

The Rolling Stone Gathers No Moss

Posted by on January 5th, 2011

But you know he’ll always keep movin’ You know he’s never gonna stop movin’ Cause he’s rollin’, he’s a rollin’ stone ~ Baker Street, by Gerry Rafferty (Link to Song on Youtube) Something to ponder. whether you’re a rock star or researcher, you’re bound to be on the road at some point. Seldom do researchers[…]

In Development this week (Vol. 138, Issue 3)

Posted by on January 4th, 2011

Here are the research highlights from the new issue of Development: Wnt/PCP signalling, microtubules and gastrulation During vertebrate gastrulation, convergence and extension (C&E) movements shape the germ layers to form the anterioposteriorly elongated body axis of vertebrate embryos. Non-canonical Wnt/planar cell polarity (Wnt/PCP) signalling regulates C&E by polarising the morphology and behaviour of cells, which[…]

Celebrating NYE with Bioluminescence

Posted by on December 31st, 2010

Let me take you on a Bioluminescent journey across many kingdoms. If you’re not well acquainted with the term, it’s the ability of living things to chemically produce light. It’s also a natural widespread feature to many organisms, from jellyfish to algae, fireflies to fungi. In recent years, it’s become a standard molecular biological tool for[…]