the community site for and by developmental biologists

Nippon

Posted by on October 12th, 2010

Dear Reader, My name is Dávid Molnár, I’m a third year Ph.D. student in the Department of Human Morphology and Developmental Biology at Semmelweis University (Budapest, Hungary). I’d like to share the story of my summer internship with You! Thanks to the generous offer of Guojun Sheng, the team leader of the Laboratory for Early[…]

In Development this week (Vol. 137, Issue 21)

Posted by on October 12th, 2010

Here are the research highlights from the current issue of Development: Oct1: essential for trophoblast development Most POU family transcription factors are temporally and spatially restricted during development and play pivotal roles in specific cell fate determination events. Oct1 (Pou2f1), however, is ubiquitously expressed in embryonic and adult mouse tissues; so, does Oct1 have a[…]

FASEB Excellence in Science Award for Gail Martin

Posted by on October 7th, 2010

The FASEB Excellence in Science Award is awarded annually to a woman whose research has made an exceptional contribution to the field of biological sciences. In 2011, this award will go to developmental biologist Gail Martin, of the University of California, San Francisco. Martin’s current work focuses mainly on the role of FGF signalling in[…]

American plant research gets a boost

Posted by on October 7th, 2010

In the US, basic plant research is relatively underfunded compared to other fields, with most of the available money going directly towards the development of practical agricultural applications. Last year, the Howard Hughes Medical Institute (HHMI) organized a meeting called “Future Horizons in Plant Science”, where select scientists in the field concluded that there was[…]

Stunning cysts

Posted by on October 6th, 2010

Hello to all of you Node readers!  My name is Erin Campbell and I’m the blogger behind HighMag Blog, a blog that features cell biology images a few times a week.  The great Eva Amsen contacted me about featuring some images on The Node, so I’m excited to be part of this growing community forum. […]

Nobel Prize for Robert Edwards

Posted by on October 4th, 2010

Robert Edwards has just been announced as winner of the 2010 Nobel Prize in Physiology or Medicine, for his work on in vitro fertilization (IVF) We speculated about the winners a few weeks ago, and he was not among anyone’s guesses, but this is a very exciting and timely choice. Just last Friday I mentioned[…]

Who will regulate UK embryo research?

Posted by on October 1st, 2010

In an attempt to tighten the country’s budget, the UK government wants to cut a large number of arms-length non-governmental organisations. These “quangos” (quasi-autonomous non-governmental organizations) include regulatory bodies, advisory organs, and other committees. Until last week, there were only vague speculations as to which funds would be cut, but the news has become more[…]

An interview with Irving Weissman at the 2010 ISSCR meeting

Posted by on September 30th, 2010

(This interview originally appeared in Development on September 28, 2010) The International Society for Stem Cell Research (ISSCR) held their annual conference in San Francisco this June. At the time, the President of the society was Irving Weissman, who is currently on the board of directors of the ISSCR as past President. He is Professor[…]

In Development this week (Vol 137, Issue 20)

Posted by on September 28th, 2010

A fateful look at early mouse lineage specification The first cell lineages specified in the mouse embryo are the trophectoderm (TE), which generates the embryonic portion of the placenta, and the inner cell mass (ICM). The ICM subsequently forms the pluripotent epiblast (EPI, which produces the embryo) and the primitive endoderm (PrE, which generates other[…]

Pleiades Promoter Project

Posted by on September 27th, 2010

A recent paper in PNAS describes the development of MiniPromoters: human DNA promoters of less than 4 kb, designed to drive gene expression in specific areas of the brain. The initiative is called the Pleiades Promoter Project, and so far they have confirmed brain-region specific activity in knockin mice for 27 of their MiniPromoters. The[…]