the community site for and by developmental biologists

Live imaging of stem cell maintenance, loss, and renewal in the Drosophila testis

Posted by on July 28th, 2011

Stem cells have often been imaged live in culture, but very few stem cell systems are conducive to live imaging within their native tissues.  An essential property of adult stem cells that they are maintained at specific anatomical locations called niches.  The interactions between stem cells and their niche are crucial, but are often disrupted[…]

From the Embryology 2011 Class: 4th of July Parade

Posted by on July 26th, 2011

Because Woods Hole, MA is home to both an Oceanographic Institute and the Marine Biological Laboratory, most of the people in this small town have some connection to the scientific community. As a result, the fourth of July festival in Woods Hole, MA is a celebration of uninhibited science-geekery. Some of the highlights included the[…]

In Development this week (Vol. 138, Issue 16)

Posted by on July 26th, 2011

Here are the research highlights from the current issue of Development: Pushing the nuclear envelope Not all nuclei are regular spheres as is often shown in textbooks. For example, in Drosophila embryos, nuclei are initially spherical but they elongate and acquire an irregular lobulated morphology during cellularisation. These morphological changes coincide with transcriptional activation of[…]

Top Developmental Biologists meet in Chile for a laboratory and lecture course: open to Latin American and International applicants

Posted by on July 25th, 2011

Top Developmental Biologists meet in Chile for a laboratory and lecture course

Biology Open – Be one of the first to submit

Posted by on July 22nd, 2011

Biology Open is a new journal, launching in September 2011, from The Company of Biologists, publishers of Development, Disease Models & Mechanisms, Journal of Cell Science and The Journal of Experimental Biology. The journal is online-only and Open Access and will publish peer-reviewed research across all aspects of the biological sciences. Biology Open will aim[…]

Visualize it!

Posted by on July 19th, 2011

Here’s a short “behind the scenes” on our paper about visualizing gene expression data, published in Nucleic Acids Research. When I joined James Briscoe‘s lab as a postdoc, my project’s ultimate goal was (and still is) to decipher and model the gene regulatory network underlying neural tube patterning. For this, I need to know where,[…]

In touch with your feminine side? Not like a butterfly (or a chicken)

Posted by on July 18th, 2011

Last week, the butterfly keepers at the Natural History Museum in London came across an incredibly rare phenomenon: a lateral gynandromorph. This butterfly is both male and female, and the division is bilateral, with the left half being male and the right female. This occurrence is almost certainly the result of chance improper separation of[…]

ISSCR 9th Annual Meeting (Toronto, June 2011) – Day 4: Saturday 18th

Posted by on July 15th, 2011

Welcome to my report from the 9th Annual ISSCR Meeting in Toronto, 2011. This is  the final part, covering the events of day four of the conference (Saturday); Follow these links to read my account of day one, day two, and day three. Day 4 – Saturday 18th June There is a great amount of[…]

ISSCR 9th Annual Meeting (Toronto, June 2011) – Day 3: Friday 17th

Posted by on July 15th, 2011

Welcome to my report from the 9th Annual ISSCR Meeting in Toronto, 2011. This is  part three, covering the events of day three of the conference (Friday); you can read the coverage from day one here and day two here. Day 3 – Friday 17th June Starting off the day and the ‘Reprogramming and Fate[…]

ISSCR 9th Annual Meeting (Toronto, June 2011) – Day 2: Thursday 16th

Posted by on July 15th, 2011

Welcome to my report from the 9th Annual ISSCR Meeting in Toronto, 2011. This is  part two, covering the events of day two (Thursday) of the conference, you can see part one here. Day 2 – Thursday 16th June Arriving late at the first plenary of the day, “Tissue Stem Cell Origins”, I managed to[…]