PhD position – Shutting down the power of brain tumour initiation cells

A PhD studentship is available in Dr. Claudia Barros’ group, Peninsula School of Medicine, Plymouth University, UK. The project is devoted to characterise the role of novel candidate genes in brain tumour initiation identified in the laboratory. It will focus on investigating pathways acting in mitochondria, the cells’ power plants, but it is not restricted to it. Drosophila will be used to examine candidate genes in the conversion of normal neural stem lineage cells into brain tumour initiation cells via gain and loss of function assays, providing a unique opportunity to unravel their role in live brains at single-cell resolution. Translation of findings will be performed using glioma tumour samples and patient-derived glioblastoma stem cell lines.

We are looking for a candidate with experience in genetics, molecular biology, immunohistochemistry, cell culture, biochemistry and/or confocal imaging. A high interest in neural stem cell and brain tumour biology is a must. Applications are invited from qualified graduates (1^st class or 2:1, equivalent), and preferably a relevant Masters or extended laboratory research experience. International students must have an IELTS score of min 7.0 (with no less than 6.5 in any element).

For further information regarding the project, please contact Dr. Claudia Barros (claudia.barros@plymouth.ac.uk). Applications must be made in accordance with the details shown below.

Funding Notes:
The studentship is supported for 3 years and includes full Home/EU tuition fees plus a stipend of £14,553 per annum.  The studentship will only fully fund those applicants who are eligible for Home/EU fees with relevant qualifications.  Applicants required to cover overseas fees will have to cover the difference between the Home/EU and the overseas tuition fee rates. For the 17/18 academic year the difference in fee is £10350. If you are selected you will be required to provide financial assurances.

To Apply:

Follow the link https://www.plymouth.ac.uk/student-life/your-studies/the-graduate-school/applicants-and-enquirers and click ‘Apply Now’ to access the application form.  Please mark the application for the attention of Francesca Niedzielski. Please Note:  you do not need to submit a project proposal with your application.

For questions on the admissions process contact pupsmd-researchdegreesadmissions@plymouth.ac.uk  

Closing date for applications is 29th April 2018. 

Shortlisted candidates will be invited for interview. We regret that we may not be able to respond to all applications.  Applicants who have not received an offer of a place by end of May 2018 should consider their application has been unsuccessful on this occasion.

Reference number: PUPSMD-17-18-014

Start date: 1st October 2018

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