Post Doctoral Researcher Position
German Centre for Diabetes Research
A post-doctoral position is available in the research group of Dr Anthony Gavalas. The group investigates the role of signaling pathways and metabolism in the late stages of endocrine pancreas development, the application of novel signals for the conversion of human pluripotent stem cells into functional beta cells and the function of adult pancreas stem cells. A combination of directed pluripotent stem cell differentiation, genomics, in vivo genetic analyses and ex vivo experiments using explants and organoids is being used. The project will focus on the manipulation of novel signaling pathways in endocrine pancreas specification for the efficient generation of functional beta cells from human pluripotent stem cells (https://www.digs-bb.de/research/research-groups/anthony-gavalas/).
The successful candidate will have a Ph.D. degree in Biology and related disciplines, a good publication record and extensive experience in cell culture and differentiation of human pluripotent stem cells. Experience with CRISPR-Cas9 mediated genome engineering will be an asset.
The lab is located in the Center for Regenerative Therapies Dresden (CRTD) with full access to state of the art core facilities for Deep Sequencing, including single cell RNA Seq, Genome Engineering, Imaging and FACS analysis.
The salary will be according to the TV-L scale commensurate with experience and qualifications. The contract will be initially for two years with the possibility for renewal. Applicants are requested to send their CVs along with names and emails of at least two referees to Dr Anthony Gavalas (Anthony.Gavalas@tu-dresden.de).