We are seeking a creative and exceptionally motivated candidate to fill a post-doctoral position in the field of cardiac development and regeneration. Research in the Radice lab investigates the molecular mechanisms regulating how heart muscle cells sense and respond to mechanical force. Our lab discovered that N-cadherin/catenin cell adhesion complex together with the underlying cytoskeleton transmits force into the cell and activates signaling events that control cardiomyocyte proliferation (Li et al., Circ. Res. 2015; Vite et al., Development 2018). The successful applicant will apply state-of-the-art confocal microscopy techniques, utilize mouse genetics, biochemistry, and CRISPR to dissect the signal pathways, by which mechanotransduction guides the regenerative program.
Candidates should hold a Ph.D. and/or M.D. with research training in the fields of cellular and molecular biology. The project utilizes genetically altered mouse models and primary cell culture. Experience in cardiomyocyte isolation and neonatal cardiomyocyte culture is highly preferred. Background in mechanobiology is desirable. Qualified candidates should possess strong communication and interpersonal skills, attention to detail, self-motivation, and the ability to work independently. The position provides an exciting opportunity to work at the interface of basic and translational research in a highly collaborative, friendly and stimulating environment, and gain experience in a diverse set of technical approaches at the cutting edge of developmental and regenerative biology. Brown offers a world-class research environment http://cvrc.brownmedicine.org/, very attractive benefits, and an appealing location in historic Providence, RI.
Interested applicants should send a single PDF file including:
1) Cover letter (please state how you heard about the position)
2) CV demonstrating publication of impactful work
3) One-page statement of research interests
4) Contact information for three references
Please email your application to Glenn Radice (firstname.lastname@example.org) using the subject heading “Postdoctoral Fellow position”.
Glenn Radice, Ph.D.
Professor of Medicine
Cardiovascular Research Center, Rhode Island Hospital
Department of Medicine, Cardiology Division
The Warren Alpert Medical School of Brown University