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Displaying posts with the tag: cell-division [Clear Filter]

Plant stem cells strive towards equality

Posted by on February 8th, 2019

By George Bassel and Iain Johnston Multicellular organs consist of collections of cells which come together to achieve what individual cells cannot. The establishment of order in complex tissues has long been a subject of interest, dating back to the origins of microscopy itself. Previous studies have proposed rules which predict when a cell will[…]

Revisiting an old puzzle with high-resolution, three-dimensional eyes

Posted by on September 19th, 2018

Sha Wang, Deborah Gumucio This article shares the story behind our recent Developmental Cell paper. It tells the history of this project and how three-dimensional (3D) observations at the individual cell level transformed our preconceived ideas and brought new insights into cell dynamics in the proliferative intestinal epithelium.   Epithelial tubes are present in many[…]

The people behind the papers – Ximena Anleu Gil & Dominique Bergmann

Posted by on July 18th, 2018

Asymmetric division is a widespread mechanism for generating cellular diversity during developmental patterning. The stomata of flowering plants are epidermal valves that regulate gas exchange, and provide an accessible system to investigate the mechanisms of asymmetric cell division both within and across species. A paper in the new issue of Development reports an investigation of the molecular control of this[…]

Sensing and making sense of clonal fragmentation in developing tissues

Posted by on March 23rd, 2018

Steffen Rulands and Benjamin Simons A discussion of our recent paper: Rulands S et al., Universality of clone dynamics during tissue development. Nature Physics | doi:10.1038/s41567-018-0055-6   Often, the most enjoyable research projects are the ones that were never planned; and so it was with the current study.   In developmental biology, genetic lineage tracing[…]

The people behind the papers – Diane Shakes & friends

Posted by on September 20th, 2017

Development often involves the asymmetric partitioning of cellular components to daughters, and this process is crucial for successful gametogenesis. Today’s paper, published in the current issue of Development, explores the cytoskeletal mechanisms of spermatogenesis in different nematode species. We met the multi-lab team behind the work, starting with Diane Shakes (The College of William and Mary in[…]

From our sister journals- March 2016

Posted by on March 18th, 2016

Here is some developmental biology related content from other journals published by The Company of Biologists.           Drosophila as a model to study human disease The latest issue of Disease Models & Mechanisms highlights the translational impact of Drosophila research. In this issue, Moulton and Letsou review several Drosophila models of human inborn errors of[…]

A key component of cell division comes to light

Posted by on June 30th, 2014

Jens Lüders leads the Microtubule Organization laboratory (Photo: Battista/Minocri, IRB Barcelona)  “la Caixa” PhD student Nicolas Lecland is the first author of the study published in Nature Cell Biology (Photo: Battista/Minocri, IRB Barcelona) A breakthrough at IRB Barcelona fills a knowledge gap in understanding how the cell division apparatus, the mitotic spindle, is formed. The[…]