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Differentiating cells mechanically limit progenitor cells’ interkinetic nuclear migration to secure apical cytogenesis

Posted by on July 17th, 2018

Press release for Yuto Watanabe, Takumi Kawaue and Takaki Miyata‘s new Development paper   Key Points Developing brains use a mechanism like the Otoshi-buta (the drop lid), a kitchen wisdom. Differentiating cells in embryonic cerebral walls form a dense filter-like layer to mechanically barrier nuclei of neural stem cells. Loss of this barrier or fence results in[…]