the community site for and by developmental biologists

Displaying posts with the tag: disease-models-mechanisms [Clear Filter]

Paris – Cambridge – Paris: a Megakaryocyte story

Posted by on November 14th, 2016

The first news came as a shock: so the British Railways are not always perfectly on time? For an Italian, that was a massive cultural shock. The second one was even more surprising: English weather is not that bad; actually, it is better than Parisian weather. But still, I was unable, on the train from Paris to Cambridge, to stop thinking about how[…]

Intern for Disease Models & Mechanisms

Posted by on November 8th, 2016

  DMM is looking for an enthusiastic intern who wishes to gain experience in science publishing, including writing press releases, contributing to our social media activities, and supporting our Reviews Editor with commissioned articles. The internship is envisaged to last for 9 months at a salary of £20,000 per annum pro rata. Our interns have[…]

From our sister journals – September 2016

Posted by on October 7th, 2016

Here we highlight some developmental biology related content from other journals published by The Company of Biologists. Moran Neuhof, Michael Levin and Oded Rechavi explored the relationship between regeneration and inheritance in planaria    Ryo Nozu and colleagues provide evidence for lipid histotrophy in great white shark reproduction from a shark accidentally caught by fishermen in Okinawa.  […]

Seeking out the sweet spot in cancer therapeutics: an interview with Lewis Cantley

Posted by on September 23rd, 2016

  “…had you told me when I was 25 years old that I would be the director of a cancer center I would have been incredulous, given that I was totally into chemistry”   This is an extract from an interview that originally appeared in Disease Models and Mechanisms (available here Open Access) Paraminder Dhillon,[…]

Intern for Disease Models and Mechanisms

Posted by on September 19th, 2016

DMM is looking for an enthusiastic intern who wishes to gain experience in science publishing, including writing press releases, contributing to our social media activities, and supporting our Reviews Editor with commissioned articles. The internship is envisaged to last for up to 1 year at a salary of £15,000 p.a. Our interns have a great[…]

From our sister journals – July 2016

Posted by on July 25th, 2016

Here we highlight some developmental biology related content from other journals published by The Company of Biologists.         Aging zebrafish an ideal model Mice have been the traditional model of choice for investigating telomere shortening in aging, but zebrafish provide an upcoming complementary system with well-conserved physiology. Ferreira and colleagues discuss how fishes have helped our understanding of[…]

Insights into the pathogenic role of UVRAG in intestinal dysplasia

Posted by on May 4th, 2016

This post highlights the approach and findings of a new research article published in Disease Models & Mechanisms: ‘Stem cell-specific endocytic degradation defects lead to intestinal dysplasia in Drosophila’. This feature was written by Elan Strange as part of a graduate level seminar at The University of Alabama (taught by DMM Editorial Board member, Prof.[…]

Untangling developmentally programmed obesity: role of the serotonin system

Posted by on April 27th, 2016

This post highlights the approach and findings of a new research article published in Disease Models and Mechanisms (DMM): ‘5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats’. This feature was written by Richard Seeber as part of a graduate level seminar at The University of Alabama (taught by DMM Editorial Board[…]

A new Special Collection on ‘Model Systems in Drug Discovery’

Posted by on October 6th, 2015

Model systems, including laboratory animals, microorganisms, and cell- and tissue-based systems, are central to the discovery and development of new and better drugs for the treatment of human disease. In the latest issue, Disease Models & Mechanisms (DMM) launches a Special Collection that illustrates the contribution of model systems to drug discovery and optimisation across[…]

The case of philanthropy: bringing scientists and philanthropic donors together, for good

Posted by on August 28th, 2015

This editorial by Olivia Flatto was first published in Disease Models & Mechanisms.   Wealth is not new. Neither is charity. But the idea of using private wealth imaginatively, constructively, and systematically to attack the fundamental problems of mankind is new.” – John Gardner   Philanthropy, derived from private wealth, stands unique as a vital source of[…]