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Displaying posts with the tag: is_archive

New embryo phenotype data from the DMDD programme

Posted by , on 15 June 2018

Following our latest data release, the DMDD website (dmdd.org.uk) now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb ...

Workshop on HREM imaging and mouse phenotyping

Posted by , on 8 August 2017

Deciphering the Mechanisms of Developmental Disorders (DMDD) is a large-scale imaging and phenotyping  programme for genetically modified mouse embryos. For embryos at E14.5, the key imaging technique is High Resolution ...

9.5 million knockout mouse embryo images now available

Posted by , on 20 July 2017

A new set of DMDD embryo and placenta data has been released, taking our total dataset to 9.5 million images of around 1300 embryos. DMDD is a primary screen of ...

New complexities in relationship between gene mutation and embryo development

Posted by , on 11 April 2017

  A large-scale study of DMDD data has shown that inactivating the same gene in mouse embryos that are virtually genetically identical can result in a wide range and severity ...

Why are geneticists measuring the webbing between mouse embryo fingers?

Posted by , on 21 February 2017

A new paper published in Journal of Anatomy shows that measuring the amount of inter-digital webbing in mouse embryos between 14 and 15 days gestation is the best way to find ...

New data reveals how gene knockouts affect whole embryo gene expression

Posted by , on 7 February 2017

New DMDD data released on Expression Atlas reveals the effect of single gene knockouts on the expression of all other genes in the mouse genome. The gene expression profiles of ...

New phenotype dataset available for embryonic-lethal mouse knockouts

Posted by , on 1 December 2016

    This post originally appeared on Annotations, the DMDD blog.   New image and phenotype data for embryos and placentas from embryonic lethal knockout mouse lines has been made ...

New phenotype screen examines causes of neonatal death

Posted by , on 4 October 2016

This post first appeared on Annotations, the DMDD blog (blog.dmdd.org.uk). Around a third of targeted gene knockouts in mice are embryonic-lethal. But not all deaths occur during gestation – a ...

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