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Displaying posts with the tag: epigenetics [Clear Filter]

Silencing transposons during epigenetic reprogramming

Posted by on November 8th, 2017

Molecules called endosiRNAs help us avoid genetic chaos, according to a new study from a team at the Babraham Institute. Much of the human genome contains pieces of DNA called transposons, a form of genetic parasite. When active, transposons can damage genes so it is important to keep them inactive. At a certain point early[…]

Older wombs linked to complications in pregnant mice

Posted by on September 6th, 2017

This article is recent news from the Babraham Institute in Cambridge, view the original post here and the Nature Communications research paper here. Deciding to start a family later in life could be about more than just the age of your eggs. A new study in mice suggests the age of a mother’s womb may[…]

The people behind the papers: Rute Tomaz & Véronique Azuara

Posted by on February 15th, 2017

Embryonic stem cells express genes necessary for self-renewal, and also ‘prime’ lineage-specific genes which stay silent until differentiation; the molecular players and pathways that govern the timely gene expression are still being delineated. Today’s paper comes from the most recent issue of Development and reveals a role for the histone demethylase Jmjd2c in gene activation in stem cell[…]

Free webinar | Single-cell RNA-seq and cell heterogeneity in the central nervous system

Posted by on August 17th, 2016

Register here: http://bit.ly/single_cell_rna_seq_webinar  Interested in understanding RNA-seq and its application to the study of oligodendrocyte heterogeneity? Join Dr Gonçalo Castelo-Branco and Dr Amit Zeisel, of the the Department of Medical Biochemistry and Biophysicsat the Karolinska Institutet, as they discuss the latest developments in single cell RNA-seq. Topics covered will include Technology development, applications, and challenges Investigation of[…]

Postdoctoral position in chromatin and epigenetic control of Drosophila development

Posted by on June 30th, 2016

Stockholm University, Sweden, invites applications for one postdoctoral position in the laboratory of Professor Mattias Mannervik at the Department of Molecular Biosciences, The Wenner-Gren Institute (http://www.su.se/mbw). The position is scheduled to start as soon as possible.   Transcriptional coregulators are proteins that facilitate communication between transcription factors and the basal transcription apparatus, in part by[…]

Adventures in Studying Brain Sex Differences

Posted by on May 8th, 2015

by Peg McCarthy and Bridget Nugent The biological phenomenon of hormonally induced sexual differentiation of the brain has been an empirical topic of study for over 50 years1 but much remains to be discovered in terms of both mechanism and functional impact. In the McCarthy lab we exploit the many advantages of the laboratory rat[…]

Postdoctoral position in chromatin regulation and epigenetic control of Drosophila development

Posted by on February 19th, 2015

Stockholm University, Sweden, invites applications for one postdoctoral position in the laboratory of Professor Mattias Mannervik at the Department of Molecular Biosciences, The Wenner-Gren Institute (http://www.su.se/mbw/research/research-groups/integrative-biology/group-mannervik). The position is scheduled to start as soon as possible. Transcriptional coregulators are proteins that facilitate communication between transcription factors and the basal transcription apparatus, in part by affecting[…]

A postdoctoral position is open in an INSERM laboratory (Marseille, France) Cardiac Developmental Biology

Posted by on June 24th, 2013

Our team focuses on epigenetic regulation of determination of cardiac cell lineages using stem cells and mouse embryos. The fellow will investigate how changes in the 3D chromatin configuration affect the development of the heart.  She/he will work with both wt mouse embryos (lineage tracing, micro-ChIP, 3C technologies, DNA microinjection) and from the second year[…]

Woods Hole Images round 3 – vote for a Development cover

Posted by on June 7th, 2013

It is time for round 3 of last years’ Woods Hole embryology course images! The regenerated planarian won the last round , but who will you vote for this time? Below are 4 great images, and you can decide which one will feature in the cover of Development. To see bigger versions, just click on[…]

Post-doctoral fellowship in Cologne, Germany

Posted by on April 22nd, 2013

The Center for Molecular Medicine Cologne (CMMC) is a multidisciplinary center at the University of Cologne providing a forum that brings together physician scientists with basic researchers from the Faculty of Medicine and the Faculty of Mathematics and Natural Sciences to perform competitive basic, disease-oriented research. The mission of the CMMC is to advance the[…]