the community site for and by developmental biologists

Displaying posts with the tag: gastrulation [Clear Filter]

A Crumby affair: Cell ingression during gastrulation

Posted by on January 31st, 2017

Comment on “Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation” Ramkumar N, Omelchenko T, Silva-Gagliardi NF, McGlade CJ, Wijnholds J, Anderson KV. Nat Cell Biol. 2016 Dec;18(12):1281-1291   “It is not birth, marriage, or death, but gastrulation, which is truly the most important time in your life.” Lewis Wolpert (1986)   Aptly stated by Wolpert, gastrulation is the fundamental process[…]

The rabbit blastocyst modelling (for) vertebrate gastrulation

Posted by on January 5th, 2015

Form and function of animal gastrulation have been longstanding classics accompanying the rise of experimental embryology, and – as if to square the circle in the literal sense – the blastopore of Haeckel’s original ‘gastrea’ stage[1] was soon (and still is) considered analogous to the straight primitive streak of birds and mammals[2-4]. Both forms are[…]

Gastrulation: Local actions, global movements and self-organisation

Posted by on June 6th, 2014

Cells move in (still) mysterious ways to achieve morphogenesis. Prominently, cells of an early vertebrate embryo (blastula, a mass of undifferentiated cells) move extensively during gastrulation to generate the three basic layers of the organism: ectoderm at the surface, endoderm presaging the digestive tube, and the mesoderm in between. At the end of the process,[…]

X-rays and frog embryos: new features of gastrulation revealed

Posted by on August 19th, 2013

For decades, the development of the early embryo and patterning of tissues has been studied with the help of a workhorse of developmental biology, the frog embryo.  Xenopus embryos are large and undergo clear morphological changes throughout their development that make them very quick and easy to work with in answering questions surrounding the formation[…]

Bio Web Conferences – Critical discussions with developmental biologists for deep learning.

Posted by on February 10th, 2012

Dear Developmental biology community, I would like to bring to your attention a potentially valuable resource for your teaching and research endeavors.  I am a neurodevelopmental biologist at Smith College.  I started teaching a course in Developmental Biology back in 2005, and since then have been utilizing web conferencing technology to bring the research behind[…]

A wave from Quintay

Posted by on January 31st, 2012

The International course on Developmental Biology was a great experience, both instructive and mind-opening. All the students were shuttled to the remote and very small fishing village of Quintay, where the CIMARQ, the investigation centre where the course took place, is located. Originally a whaling station, this centre is dedicated to the instruction of professionals[…]

Final Day at The EMBO Meeting – Behaviour and lots of Movies!

Posted by on September 14th, 2011

The famous Richard Axel kicked off the last day in Vienna by presenting new data on how olfactory information is projected from the olfactory bulb to the cortex. After his keynote lecture, the talks in the plenary session continued with a focus on the brain and how it drives behaviour in different circumstances or environments[…]

In Development this week (Vol. 138, Issue 3)

Posted by on January 4th, 2011

Here are the research highlights from the new issue of Development: Wnt/PCP signalling, microtubules and gastrulation During vertebrate gastrulation, convergence and extension (C&E) movements shape the germ layers to form the anterioposteriorly elongated body axis of vertebrate embryos. Non-canonical Wnt/planar cell polarity (Wnt/PCP) signalling regulates C&E by polarising the morphology and behaviour of cells, which[…]

An interview with Patrick Tam

Posted by on November 25th, 2010

(This interview by Kathryn Senior originally appeared in Development on November 23, 2010) Patrick Tam’s research is focused on the cellular and molecular mechanisms of body patterning during mouse development. He agreed to be interviewed by Development to talk about his interest in mouse development, new concepts in gastrulation, X-linked diseases and his dream of[…]