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Displaying posts with the tag: implantation [Clear Filter]

An interview with Jenny Nichols

Posted by on August 17th, 2017

This interview by Aidan Maartens¬†originally appeared in¬†Development, Volume 143, Issue 16. Jennifer Nichols is a Principal Investigator at the Cambridge Stem Cell Institute and Department of Physiology, Development and Neuroscience at the University of Cambridge, UK. Her lab works on lineage segregation and the establishment of pluripotency in the mammalian embryo. In 2017 she was[…]

The home of the implanting embryo: A 3D perspective

Posted by on January 5th, 2017

Comment on “Insights from imaging the implanting embryo and the uterine environment in three dimensions”, Arora et al, Development¬†143(24):4749-4754 (2016).   More than 2000 years ago, Hippocrates (460-377BC) and Aristotle (384-322BC) described the human uterus as a series of chambers with a lining of tentacles or suckers. They believed that blood vessels connected the breast[…]

The blastocyst achieves on-time implantation by entosis

Posted by on September 1st, 2015

The process of embryo implantation consists of multiple steps: blastocyst apposition, adhesion to uterine luminal epithelial (LE) cells, and removal of the epithelial cells encasing the blastocysts. How the blastocyst trophectoderm breaches the luminal epithelial barrier has been studied for decades, the mechanism of the abstraction of LE cells was not clearly understood. Since the[…]