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Displaying posts with the tag: intestine [Clear Filter]

Rare Is Everywhere

Posted by on June 5th, 2018

The story behind FOXL1+ telocytes You can find our recently published Nature paper here   Our story began two decades ago when my mentor, Klaus H. Kaestner, identified and cloned the transcription factor FOXL1, as being expressed in the mesenchyme of the mouse fetal gut (Kaestner et al. 1997). The position of FOXL1+ mesenchymal cells[…]

Stem cell fate choice: determined in an instant

Posted by on March 6th, 2018

Jun Chen National Institute of Biological Sciences, Beijing A discussion of our recent paper: Chen J, Xu N, Wang C, Huang P, Huang H, Jin Z, Yu Z, Cai T, Jiao R, Xi R. Transient Scute activation via a self-stimulatory loop directs enteroendocrine cell pair specification from self-renewing intestinal stem cells. Nat Cell Biol. 2018[…]

Intestinal stem cells- from a foetal development perspective

Posted by on December 18th, 2013

My name is Rob Fordham and I’ve just finished my PhD at the Wellcome Trust/MRC Cambridge Stem Cell Institute, University of Cambridge, supervised by Dr Kim Jensen (now Associate Professor at the Biotech Research and Innovation Center (BRIC), University of Copenhagen), and Professor Roger Pedersen.* During my PhD I was fascinated with intestinal development- and[…]