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Displaying posts with the tag: lineage-tracing [Clear Filter]

An interview with Bill Harris

Posted by on July 6th, 2017

This interview by Aidan Maartens originally appeared in Development, Volume 143, Issue 13.    William ‘Bill’ Harris is Head of the Department of Physiology, Development and Neuroscience at the University of Cambridge, UK, and a Fellow of both the Royal Society and Academy of Medical Sciences. His lab works on the development of the vertebrate[…]

Colourful life of a fruit fly

Posted by on January 22nd, 2014

Those lucky scientists, who study organisms which allow live imaging experiments to be effectively performed, do not always appreciate what a luxury it is to watch the tissue of interest develop in time. Scientists who work on less accessible models that take long time to develop to term, look with envy on the beautiful movies[…]

The embryonic cell lineage of C. elegans, revisited and revisualized

Posted by on October 26th, 2012

On my desk sits a tattered photocopy of one of the pinnacles of modern developmental biology, the “embryonic lineage” paper by John Sulston, et al. (1983). In this paper, Sulston et al. completed a project begun in the late 19th century, namely to trace the complete genealogy of all cells in a nematode embryo. C.[…]

Just because it looks like a duct, doesn’t mean it is the duct

Posted by on January 25th, 2011

The Node’s staff has kindly given me the opportunity to write a background piece, placing into context the results of our studies described in the paper, “Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas” (released today in Development; http://dev.biologists.org/lookup/doi/10.1242/dev.056499). For many[…]

Zebrafish transgenes go ubiquitous

Posted by on December 7th, 2010

The Node’s staff has kindly asked me to write a little “behind the scenes” on our zebrafish paper released today in Development, “Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish” (http://dev.biologists.org/content/138/1/169). The spark to pursue the project were the first conversations I had in spring 2008 with senior postdocs in[…]