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More than papers…..

Posted by on March 26th, 2019

This is the latest dispatch from a recipient of a Development Travelling Fellowship, funded by our publisher The Company of Biologists. Learn more about the scheme, including how to apply, here, and read more stories from the Fellows here.   Estefanía Sánchez-Vásquez (Peruvian woman doing a PhD in Argentina)   Lately there is much discussion of[…]

Of mice and chicks…

Posted by on October 1st, 2018

This is the latest dispatch from a recipient of a Development Travelling Fellowship, funded by our publisher The Company of Biologists. Learn more about the scheme, including how to apply, here, and read more stories from the Fellows here.   Barbara Swierczek   I am a PhD student at the University of Warsaw in Poland. In[…]

PhD position available: The role of microRNAs in neural crest development

Posted by on November 20th, 2012

SCHOOL OF BIOLOGICAL SCIENCES, UNIVERSITY OF EAST ANGLIA   PhD POSITION AVAILABLE   The role of microRNAs in neural crest development   MicroRNAs (miR) are short, non-coding RNAs around 22 nucleotides long. They block gene expression either by translational repression or by causing the degradation of the mRNAs they bind to. They are involved in[…]

In Development This Week (Vol. 138, Issue 22)

Posted by on October 25th, 2011

Here are the highlights from the current issue of Development: The skin-healing touch of Lhx2 Skin repair after injury involves the recruitment of undifferentiated progenitor cells from nearby hair follicles (HFs) into the regenerating epidermis. The bulge and the secondary hair germ of HFs contain distinct populations of epithelial stem cells, and now Vladimir Botchkarev[…]

In Development this week (Vol. 138, Issue 9)

Posted by on April 12th, 2011

Here are the research highlights from the current issue of Development: Cranial neural crest development: p53 faces up The tumour suppressor p53 plays multiple roles in the prevention of cancer but its developmental functions are less clear. Here (see p. 1827), Eldad Tzahor and colleagues elucidate the key role that p53 plays in craniofacial development.[…]

In Development this week (Vol. 138, Issue 7)

Posted by on March 8th, 2011

Here are the research highlights from the current issue of Development: A breath of fresh air: miRNAs regulate lung development Throughout development, a proper balance between the proliferation and differentiation of progenitor cells is essential but the gene regulatory networks that control this balance are only partly understood. Here, Edward Morrisey and colleagues report that[…]

Arrested Development in Plant miRNA Mutants

Posted by on January 11th, 2011

Animals and Plants have hundreds of miRNAs with diverse roles in gene regulation. In humans, each miRNA family can control up to several hundred genes (or 500 to be exact, in humans). A loss of function in one, can lead to array of developmental defects. Similarly in plants, an miRNA mutant can have a variety of phenotypes. However, interestingly, many miRNAs only have one target, which is frequently a transcription factor that in turn, controls many genes itself. It’s really like a house of cards.

In the new issue of Development, 137 (17)…

Posted by on August 10th, 2010

The Bicoid gradient, epigenetic control of BMP signalling, haematopoietic stem cells and more…here are the highlights from the current issue of Development: The Bicoid gradient gets into shape without nuclei Morphogen gradients provide key positional information during embryogenesis but how they are established is not well understood. A gradient of the transcription factor Bicoid is[…]