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Displaying posts with the tag: neural-stem-cells [Clear Filter]

Gene editing stem cells with CRISPR could help understand brain tumours

Posted by on February 14th, 2017

This report written by Justine Alford and highlighting a recent Development paper originally appeared on the CRUK Science Blog.      Over the past 12 months, the acronym CRISPR has been popping up in science news left, right and centre. And for good reason. Hailed as a revolution in genetic engineering, this molecular toolbox lets[…]

The people behind the papers #13

Posted by on February 8th, 2017

Radial glial cells are multipotent progenitors in the developing vertebrate brain. At their apical interface with the ventricular cavity around which the brain forms, they bear a primary cilium, a signalling and sensory organelle crucial for proper brain development. Today’s paper, from a recent issue of Development, addresses the link between these primary cilia and brain morphogenesis.[…]

Deep into the developmental origins of neural tumours with Drosophila

Posted by on July 12th, 2016

Caroline Dillard and Cédric Maurange (Aix-Marseille University, CNRS, IBDM, Marseille)   Drosophila neural stem cells as a cancer model Transformation of a cell into a cancer cell is a complex process along which the cell acquires hallmarks as diverse as resistance to differentiation, infinite proliferative potential, metastasis, resistance to cell death, genome instability (Hanahan and[…]

Post-doctoral scientist –Peter MacCallum Cancer Centre, Melbourne, Australia

Posted by on November 21st, 2011

Applications are invited for a post-doctoral research scientist post in Melbourne, to join a newly funded research group within the Cancer Cell Biology Program. The research focuses on understanding the mechanisms regulating the growth of neural stem cell derived tumours in Drosophila. We are part of a vibrant fly community working alongside 400 cancer biologists[…]

Aging stem cells

Posted by on October 12th, 2011

There are so many factors for a stem cell to consider when deciding cell fates.  A recent paper from Development discusses how the age of a stem cell can affect its future. Neurons and glial cells are two major cell types in the nervous system, and both come from the many divisions of neural stem[…]

Company of Biologists Workshop – Growth, Division and Differentiation – Day 3 – afternoon

Posted by on October 7th, 2011

As a follow up to Ben Martynoga’s post from yesterday, here is some more information on the topics covered in this excellent workshop that took place a couple of weeks ago. After extensive revolutions around the cell cycle in many of the previous sessions, Ryoichiro Kageyama introduced quite a different rhythm to the meeting in[…]

Company of Biologists Workshop – Growth, Division and Differentiation – Day 2

Posted by on September 26th, 2011

-By Nitin Sabherwal, Eugen Nacu, Heike Laman, Irene Gutierrez Vallejo and Anna Kicheva The second day of the workshop has finished and it is the reporting time now. We had a wonderful day with fantastic talks and a nice walk around the area. The weather had also been beautifully supportive for these kinds of excursions[…]

In Development this week (Vol. 138, Issue 8):

Posted by on March 22nd, 2011

Here are the research highlights from the current issue of Development: Fishing out adult neural stem cells Adult neural stem cells (NSCs) hold great potential for the treatment of neurodegenerative diseases and nervous system injuries. To date, adult neurogenesis has been mainly studied in rodents but, on p. 1459, Laure Bally-Cuif and co-workers use GFP-encoding[…]

Conference announcement: Advances in stem cell research: Development, Regeneration & Disease in Paris, France

Posted by on January 19th, 2011

Announcement for the Advances in stem cell research: Development, Regeneration & Disease conference at the Pasteur Institute, Paris, April 6-8, 2011.

An interview with Kate Storey and Silvia Marino

Posted by on May 27th, 2010

(Originally published in Development) In February 2010, in the beautiful setting of Wiston House, nestled at the foot of the hilly South Downs in Sussex, UK, The Company of Biologists, the not-for-profit organisation that publishes Development, held the inaugural meeting of their new workshop series dedicated to biological research. The meeting was titled ‘Neural Stem[…]