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Displaying posts with the tag: planar-cell-polarity [Clear Filter]

Polarizing morphogenesis: epithelia dance the polonaise

Posted by on June 13th, 2018

The story behind our recent paper: Counter-rotational cell flows drive morphological and cell fate asymmetries in mammalian hair follicles. Maureen Cetera, Liliya Leybova, Bradley Joyce & Danelle Devenport, Nature Cell Biology.    Planar cell polarity (PCP) is a fascinating biological problem because it spans such vast biological scales, from nanometers to meters of spatial organization. When[…]

Postdoctoral Associate – Cell Polarity and Development of the Inner Ear

Posted by on May 28th, 2017

    How do we perceive sounds, gravity or head movements? It all starts during development, when sensory cells in the inner ear acquire a crown of motion detectors known as the stereocilia bundle. The Tarchini laboratory investigates the molecular mechanisms that corral and layer stereocilia into a functional bundle, a highly polarized architectural process that,[…]

In Development this week (Vol. 138, Issue 5)

Posted by on February 8th, 2011

Here are the highlights from the current issue of Development: From pluripotent to pancreatic fates A reliable method for generating insulin-producing β-cells from human pluripotent stem cells (hPSCs) would provide new therapeutic options for people with diabetes. So far, no-one has developed such a method but, on p. 861, Gordon Keller and colleagues provide new[…]