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Displaying posts with the tag: stem-cells [Clear Filter]

Abcam & the Node meeting reporter competition winner: Zubair Nizamudeen

Posted by on March 20th, 2018

Earlier in the year we and Abcam ran a competition to find a meeting reporter for the upcoming Abcam Adult Neurogenesis meeting to be held in Dresden in May. Today we are delighted to announce the winner: Zubair Nizamudeen, a PhD student in Virginie Sottile’s lab at the Wolfson STEM Centre, School of Medicine, University of Nottingham, UK. Zubair’s[…]

In vivo profiling of chromatin accessibility with CATaDa

Posted by on March 13th, 2018

The following post is an introduction into the technnique described in our recent paper: Aughey, G.N., et al., CATaDa reveals global remodelling of chromatin accessibility during stem cell differentiation in vivo. Elife, 2018. 7.   Attempting to understand the biology of a complex organ, like the brain, comes with an array of technical challenges. Those[…]

Stem cell fate choice: determined in an instant

Posted by on March 6th, 2018

Jun Chen National Institute of Biological Sciences, Beijing A discussion of our recent paper: Chen J, Xu N, Wang C, Huang P, Huang H, Jin Z, Yu Z, Cai T, Jiao R, Xi R. Transient Scute activation via a self-stimulatory loop directs enteroendocrine cell pair specification from self-renewing intestinal stem cells. Nat Cell Biol. 2018[…]

Using human development to improve myogenesis from human pluripotent stem cells

Posted by on February 21st, 2018

A discussion of our recent paper: Hicks et al., ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs. Nature Cell Biology, January 1 2018   Approaching the problem of muscle disease with cell replacement therapy We will all be affected by a muscle wasting disease in our lifetime. The[…]

The people behind the papers – Marina Matsumiya & Ryoichiro Kageyama

Posted by on February 19th, 2018

Vertebrate segmentation involves the periodic formation of somites from the presomitic mesoderm, in a manner controlled by oscillating gene expression (the oscillations of the segmentation clock must be one of the marvels of nature!). While in vivo work has provided a framework for studying the process, many aspects of segmentation dynamics are obscured in the embryo. A new Techniques[…]

YEN Conference 2018: Abstract submission and registration is open!

Posted by on February 3rd, 2018

Young Embryologist Network Conference 2018 14th May 2018 The Francis Crick Institute, London, UK   This year we are pleased to announce Professor Wolf Reik as our keynote speaker. His research group, based at the Babraham Institute, investigates the roles of epigenetic gene regulation in mammalian development. We are also honoured to have Dr Susan Cox and Dr[…]

Uncovering the early origins of Huntington’s disease

Posted by on January 29th, 2018

With new findings, scientists may be poised to break a long impasse in research on Huntington’s disease, a fatal hereditary disorder for which there is currently no treatment.     One in 10,000 Americans suffer from the disease, and most begin to show symptoms in middle age as they develop jerky movements—and as these patients[…]

The future of human reproduction: Stepping back from visions of Gattaca

Posted by on January 16th, 2018

The impact of developmental biology on society is particularly acute when it comes to reproduction – research informs efforts to assist reproduction and understand what happens when pregnancy goes wrong. Recent developments in stem cells, culturing conditions, gene editing and sequencing are also revealing aspects of human embryonic development previously hidden from us. Here at[…]

Post Doctoral Position on Pancreas Development and Stem Cells

Posted by on January 15th, 2018

Post Doctoral Researcher  German Centre for Diabetes Research Dresden A post-doctoral position is available in the research group of Dr Anthony Gavalas. The group investigates the role of signaling pathways and metabolism in the late stages of endocrine pancreas development, the application of novel signals for the conversion of human pluripotent stem cells into functional[…]

PhD student position –  Max Planck Institute for Molecular Biomedicine

Posted by on December 15th, 2017

TheMax-Planck-Institute for Molecular Biomedicine in Muenster, Germany has an opening for a PhD student (position-code 15-2017). The position The position is available in the group of Dr. Ivan Bedzhov that is focused on understanding the self-organization of early mammalian embryos and stem cells. The successful candidate will investigate the mechanisms of spatiotemporal organization and cell fate transitions of[…]