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Travelling Fellowships from The Company of Biologists: Deadline approaching!

Posted by on November 20th, 2018

The Company of Biologists’ journals – Development, Journal of Cell Science, Journal of Experimental Biology and Disease Models & Mechanisms – offer Travelling Fellowships of up to £2,500 to graduate students and post-doctoral researchers wishing to make collaborative visits to other laboratories. These are designed to offset the cost of travel and other expenses. There is no restriction on nationality. They really[…]

In vivo profiling of chromatin accessibility with CATaDa

Posted by on March 13th, 2018

The following post is an introduction into the technnique described in our recent paper: Aughey, G.N., et al., CATaDa reveals global remodelling of chromatin accessibility during stem cell differentiation in vivo. Elife, 2018. 7.   Attempting to understand the biology of a complex organ, like the brain, comes with an array of technical challenges. Those[…]

Using human development to improve myogenesis from human pluripotent stem cells

Posted by on February 21st, 2018

A discussion of our recent paper: Hicks et al., ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs. Nature Cell Biology, January 1 2018   Approaching the problem of muscle disease with cell replacement therapy We will all be affected by a muscle wasting disease in our lifetime. The[…]

Electrifying news for embryologists

Posted by on June 17th, 2014

Electroporation: an efficient technique for embryologists During embryonic development, the specification of different cell types giving rise to the future organs involves a precise spatiotemporal regulation of cell proliferation, migration, and differentiation. Studying these processes requires tools to manipulate gene expression locally in the developing embryo.To this aim, embryologists have widely used the technique of[…]