March in preprints
Posted by the Node, on 2 April 2020
Welcome to our monthly trawl for developmental biology (and related) preprints.
In lock down you might find yourself with more time to read; reading some science might also be a welcome distraction from the pandemic. Lots of fascinating stuff in March, hosted on bioRxiv and arXiv– let us know if we missed anything. Use these links to get to the section you want:
Developmental biology
| Stem cells, regeneration & disease modelling
Evo-devo & evo
Cell biology
Modelling
Tools & resources
Research practice & education
Developmental biology
| Patterning & signalling
Tissue interactions govern pattern formation in the posterior lateral line of medaka
Lazaro Centanin, Ali Seleit, Karen Gross, Jasmin Onistschenko, Oi Pui Hoang, Jonas Theelke
In situ differentiation of iridophore crystallotypes underlies zebrafish stripe patterning
Dvir Gur, Emily Bain, Kory Johnson, Andy J. Aman, Amalia Pasoili, Jessica D. Flynn, Michael C. Allen, Dimitri D. Deheyn, Jennifer C. Lee, Jennifer Lippincott-Schwartz, David Parichy
De Novo Phosphoinositide Synthesis in Zebrafish Is Required for Triad Formation but Not Essential for Myogenesis
Lindsay Smith, Lacramioara Fabian, Almundher Al-Maawali, Ramil R. Noche, James J. Dowling
A TgfβRI/Snai1-dependent developmental module at the core of vertebrate axial elongation
André Dias, Anastasiia Lozovska, Filip J. Wymeersch, Ana Nóvoa, Anahi Binagui-Casas, Daniel Sobral, Gabriel G. Martins, Valerie Wilson, Moisés Mallo
Axial skeleton anterior-posterior patterning is regulated through feedback regulation between Meis transcription factors and retinoic acid
Alejandra C. López-Delgado, Irene Delgado, Vanessa Cadenas, Fátima Sánchez-Cabo, Miguel Torres
Notch effector Hes1 marks an early perichondrial population of skeletal progenitor cells at the onset of endochondral bone development
Yuki Matsushita, Mizuki Nagata, Joshua D. Welch, Sunny Y. Wong, Wanida Ono, Noriaki Ono
Her9/Hes4 is required for retinal photoreceptor development, maintenance, and survival
Cagney E. Coomer, Stephen G. Wilson, Kayla F. Titialii-Torres, Jessica D. Bills, Laura A. Krueger, Rebecca A. Petersen, Evelyn M. Turnbaugh, Eden L. Janesch, Ann C. Morris
Genetic Interplay Between Transcription Factor Pou4f1/Brn3a and Neurotrophin Receptor Ret In Retinal Ganglion Cell Type Specification
Vladimir Vladimirovich Muzyka, Tudor Constantin Badea
Nkx2-5 defines distinct scaffold and recruitment phases during formation of the cardiac Purkinje fiber network
Caroline Choquet, Robert G. Kelly, Lucile Miquerol
Groucho/TLE opposes axial to hypaxial motor neuron development
Adèle Salin-Cantegrel, Rola Dali, Jae Woong Wang, Marielle Beaulieu, Mira Deshmukh, Ye Man Tang, Stefano Stifani
ZFP423 regulates early patterning and multiciliogenesis in the hindbrain choroid plexus
Filippo Casoni, Laura Croci, Francesca Vincenti, Paola Podini, Luca Massimino, Ottavio Cremona, G. Giacomo Consalez
CyclinD1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1
Satoshi Miyashita, Tomoo Owa, Yusuke Seto, Mariko Yamashita, Shogo Aida, Tomoki Nishioka, Kozo Kaibuchi, Yoshiya Kawaguchi, Shinichiro Taya, Mikio Hoshino
Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain
Rebecca M. Beiter, Anthony Fernández-Castañeda, Courtney Rivet-Noor, Andrea Merchak, Robin Bai, Erica Slogar, Scott M. Seki, Dorian A Rosen, Christopher C. Overall, Alban Gaultier
Diminished ventral oligodendrocyte precursor generation results in the subsequent over-production of dorsal oligodendrocyte precursors of aberrant morphology and function
Lev Starikov, Andreas H. Kottmann
Gsx2 is involved in specification of neurons in the inferior olivary nuclei from Ptf1a-expressing neuronal progenitors in zebrafish
Tsubasa Itoh, Miki Takeuchi, Marina Sakagami, Kazuhide Asakawa, Koichi Kawakami, Takashi Shimizu, Masahiko Hibi
Choroid plexus APP regulates adult brain proliferation and animal behavior
Karen Arnaud, Vanessa Oliveira Moreira, Jean Vincent, Glenn Dallerac, Chantal Le Poupon, Max Richter, Ulrike C. Müller, Laure Rondi-Reig, Alain Prochiantz, Ariel A. Di Nardo
Adult-born hippocampal neurons undergo extended development and are morphologically distinct from neonatally-born neurons
John Darby Cole, Delane Espinueva, Désirée R. Seib, Alyssa M. Ash, Matthew B. Cooke, Shaina P. Cahill, Timothy O’Leary, Sharon S. Kwan, Jason S. Snyder
CREB non-autonomously regulates Reproductive Aging through Hedgehog/Patched Signalling
Nicole M. Templeman, Vanessa Cota, William Keyes, Rachel Kaletsky, Coleen T. Murphy
Prdm8 regulates pMN progenitor specification for motor neuron and oligodendrocyte fates by modulating Shh signaling response
Kayt Scott, Rebecca O’Rourke, Austin Gillen, Bruce Appel
Mitofusin2 cooperates with Nuage-associated proteins and involves mRNA translational machinery in controlling mRNA fates during spermatogenesis
Xiaoli Wang, Yujiao Wang, Jin Zhang, Shuangshuang Guo, Congcong Cao, Stephen A Krawetz, Zhibing Zhang, Shuiqiao Yuan
Production of Hyaluronan by the Trophectoderm is a Prerequisite for Mouse Blastocyst Attachment
Ron Hadas, Eran Gershon, Aviad Cohen, Michal Elbaz, Shifra Ben-Dor, Fortune Kohen, Nava Dekel, Michal Neeman
Somatic cell-derived BMPs induce male germ cell meiosis initiation during embryonic stage via regulating Dazl expression
Lianjun Zhang, Yaqiong Li, Yuqiong Hu, Limei Lin, Jingjing Zhou, Min Chen, Yan Qin, Yang Zhou, Min Chen, Xiuhong Cui, Fuchou Tang, Fei Gao
Characterization of interstitial heterogeneity in the developing kidney
Alicia R. England, Christopher P. Chaney, Amrita Das, Mohita Patel, Alicia Malewsak, Daniel Armendariz, Gary Hon, Douglas Strand, Keri Drake, Thomas J. Carroll
Foxi1 inactivation rescues loss of principal cell fate selection in Hes1-deficient kidneys but does not ensure maintenance of principal cell gene expression
Malini Mukherjee, Jennifer DeRiso, Madhusudhana Janga, Eric Fogarty, Kameswaran Surendran
Age-Dependent Changes in the Progenitor Translatome Coordinated in part by Tsc1 Increase Perception of Signaling Inputs to End Nephrogenesis
Eric Brunskill, Alison Jarmas, Praneet Chaturvedi, Raphael Kopan
Nephron progenitor maintenance is controlled through FGFs and Sprouty1 Interaction
Sung-Ho Huh, Ligyeom Ha, Hee-Seong Jang
MRI of Capn15 knockout mice and analysis of Capn15 distribution reveal possible roles in brain development and plasticity
Congyao Zha, Carole A Farah, Vladimir Fonov, David A. Rudko, Wayne S Sossin
A concept shift in the mechanistic understanding of HIFα-regulated developmental myelination
Sheng Zhang, Yan Wang, Bokyung Kim, Fuzheng Guo
Intestinal Bacteria Maintain Adult Enteric Nervous System and Nitrergic Neurons via Toll-like Receptor 2-induced Neurogenesis in Mice
Shadi S. Yarandi, Subhash Kulkarni, Monalee Saha, Kristyn E. Sylvia, Cynthia L. Sears, Pankaj J. Pasricha
DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors
Maria M. Mikedis, Yuting Fan, Peter K. Nicholls, Tsutomu Endo, Emily K. Jackson, Sarah A. Cobb, Dirk G. de Rooij, David C. Page
Reprogramming progressive cells display low CAG promoter activity
Xiao Hu, Qiao Wu, Jian Zhang, Xinyue Chen, Amaleah Hartman, Anna Eastman, Shangqin Guo
Quantifying temperature compensation of Bicoid gradients with a fast T-tunable microfluidic device
H. Zhu, Y. Cui, C. Luo, F. Liu
Hedgehog produced by the Drosophila wing imaginal disc induces distinct expression responses in three target tissues
Ryo Hatori, Thomas B. Kornberg
Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity
Arpan C. Ghosh, Sudhir G. Tattikota, Yifang Liu, Aram Comjean, Yanhui Hu, Victor Barrera, Shannan J. Ho Sui, Norbert Perrimon
Drosophila Activin signaling promotes muscle growth through InR/dTORC1 dependent and independent processes
Myung-Jun Kim, Michael B O’Connor
Minimal structural elements required for midline repulsive signaling and regulation of Drosophila Robo1
Haley E. Brown, Timothy A. Evans
Structural and developmental principles of neuropil assembly in C. elegans
Mark W. Moyle, Kristopher M. Barnes, Manik Kuchroo, Alex Gonopolskiy, Leighton H. Duncan, Titas Sengupta, Lin Shao, Min Guo, Anthony Santella, Ryan Christensen, Abhishek Kumar, Yicong Wu, Kevin R. Moon, Guy Wolf, Smita Krishnaswamy, Zhirong Bao, Hari Shroff, William Mohler, Daniel A. Colón-Ramos
The Regulation of Developmental Diapause is Coordinated with Molting and Olfaction
Heather R Carstensen, Reinard Villalon, Johnny Vertiz, Navonil Banerjee, Elissa A Hallem, Ray L. Hong
Ancestral function of Inhibitors-of-kappaB regulates Caenorhabditis elegans development
David Brena, Joan Bertran, Montserrat Porta-de-la-Riva, Yolanda Guillén, Eric Cornes, Dmytro Kukhtar, Lluís Campos-Vicens, Lierni Fernández, Irene Pecharroman, Albert Garcia-López, Khademul Islam, Laura Marruecos, Anna Bigas, Julián Cerón, Lluís Espinosa
| Morphogenesis & mechanics
Topological defects in the nematic order of actin fibers as organization centers of Hydra morphogenesis
Yonit Maroudas-Sacks, Liora Garion, Lital Shani-Zerbib, Anton Livshits, Erez Braun, Kinneret Keren
Temporal coordination of collective migration and lumen formation by antagonism between two nuclear receptors
Xianping Wang, Heng Wang, Lin Liu, Sheng Li, Gregory Emery, Jiong Chen
In vivo characterization of chick embryo mesoderm by optical coherence tomography assisted microindentation
Marica Marrese, Nelda Antonovaité, Ben K.A. Nelemans, Ariana Ahmadzada, Davide Iannuzzi, Theodoor H. Smit
Self-organized Toll-8/Cirl GPCR asymmetry drives planar polarized cell contractility
Jules Lavalou, Qiyan Mao, Stefan Harmansa, Stephen Kerridge, Annemarie C. Lellouch, Jean-Marc Philippe, Stephane Audebert, Luc Camoin, Thomas Lecuit
Rho1 activation recapitulates early gastrulation events in the ventral, but not dorsal, epithelium of Drosophila embryos
Ashley Rich, Richard G. Fehon, Michael Glotzer
Hippo signaling promotes Ets21c-dependent apical cell extrusion in the Drosophila wing disc
Xianlong Ai, Dan Wang, Junzheng Zhang, Jie Shen
Optical flow analysis reveals that Kinesin-mediated advection impacts on the orientation of microtubules in the Drosophila oocyte
Maik Drechsler, Lukas F. Lang, Layla Al-Khatib, Hendrik Dirks, Martin Burger, Carola-Bibiane Schönlieb, Isabel M. Palacios
Transient opening of tricellular vertices controls paracellular transport through the follicle epithelium during Drosophila oogenesis
Jone Isasti-Sanchez, Fenja Münz-Zeise, Stefan Luschnig
Morphogenesis is transcriptionally coupled to neurogenesis during peripheral olfactory organ development
Raphaël Aguillon, Romain Madelaine, Harendra Guturu, Sandra Link, Pascale Dufourcq, Virginie Lecaudey, Gill Bejerano, Patrick Blader, Julie Batut
Minor spliceosome disruption causes limb growth defects without altering patterning
Kyle D Drake, Christopher Lemoine, Gabriela S Aquino, Anna M Vaeth, Rahul N Kanadia
A CTGF-YAP regulatory pathway is essential for angiogenesis and barriergenesis in the retina
Sohyun Moon, Sangmi Lee, JoyAnn Caesar, Sarah Pruchenko, Andew Leask, James A. Knowles, Jose Sinon, Brahim Chaqour
EphA7 Isoforms Differentially Regulate Cortical Dendrite Development
Carrie E. Leonard, Maryna Baydyuk, Marissa A. Stepler, Denver A. Burton, Maria J. Donoghue
| Genes & genomes
Regulation of gene expression by repression condensates during development
Nicholas Treen, Shunsuke F. Shimobayashi, Jorine Eeftens, Clifford P. Brangwynne, Michael S. Levine
A single-cell analysis of the molecular lineage of chordate embryogenesis
Tengjiao Zhang, Yichi Xu, Kaoru Imai, Teng Fei, Guilin Wang, Bo Dong, Tianwei Yu, Yutaka Satou, Weiyang Shi, Zhirong Bao
Multiple Sex-Specific Differences in the Regulation of Meiotic Progression in C. elegans
Sara M. Fielder, Rieke Kempfer, William G. Kelly
trans-homolog interaction regulates the sex-biased expression of an X-linked gene
Charalampos Chrysovalantis Galouzis, Benjamin Prud’homme
The Drosophila MLR COMPASS-like complex regulates bantam miRNA expression differentially in the context of cell fate
David J. Ford, Claudia B. Zraly, John Hertenstein Perez, Andrew K. Dingwall
Dynamic Sex Chromosome Expression in Drosophila Male Germ Cells
Sharvani Mahadevaraju, Justin M. Fear, Miriam Akeju, Brian J. Galletta, Mara MLS. Pinheiro, Camila C. Avelino, Diogo C. Cabral-de-Mello, Katie Conlon, Stafania Dell’Orso, Zelalem Demere, Kush Mansuria, Carolina A. Mendonça, Octavio M. Palacios-Gimenez, Eli Ross, Max Savery, Kevin Yu, Harold E. Smith, Vittorio Sartorelli, Nasser M. Rusan, Maria D. Vibranovski, Erika Matunis, Brian Oliver
In vivo analysis of the evolutionary conserved BTD-box domain of Sp1 and Btd during Drosophila development
David Blom-Dahl, Sergio Córdoba, Hugo Gabilondo, Pablo Carr-Baena, Fernando J. Díaz-Benjumea, Carlos Estella
Dppa2/4 Counteract De Novo Methylation to Establish a Permissive Epigenome for Development
Kristjan H. Gretarsson, Jamie A. Hackett
Transposable elements resistant to epigenetic resetting in the human germline are epigenetic hotspots for development and disease
Sabine Dietmann, Michael J Keogh, Walfred Tang, Erna Magnusdottir, Toshihiro Kobayashi, Patrick F Chinnery, M. Azim Surani
Maternal DNMT3A-dependent de novo methylation of the zygotic paternal genome inhibits gene expression in the early embryo
Julien Richard Albert, Wan Kin Au Yeung, Keisuke Toriyama, Hisato Kobayashi, Ryutaro Hirasawa, Julie Brind’Amour, Aaron Bogutz, Hiroyuki Sasaki, Matthew Lorincz
Super-enhancer switching drives a burst in germline gene expression at the mitosis-to-meiosis transition
So Maezawa, Masashi Yukawa, Xiaoting Chen, Akihiko Sakashita, Kris G. Alavattam, Matthew T. Weirauch, Artem Barski, Satoshi H. Namekawa
Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive inter- and intra-enhancer redundancy
A. Hörnblad, K. Langenfeld, S. Bastide, F. Langa Vives, F. Spitz
Discovery of genes required for body axis and limb formation by global identification of retinoic acid regulated epigenetic marks
Marie Berenguer, Karolin F. Meyer, Jun Yin, Gregg Duester
Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks
Kelsey H. Elliott, Xiaoting Chen, Joseph Salomone, Praneet Chaturvedi, Preston A. Schultz, Sai K. Balchand, Jeffrey D. Servetas, Aimée Zuniga, Rolf Zeller, Brian Gebelein, Matthew T. Weirauch, Kevin A. Peterson, Samantha A. Brugmann
Combined analysis of single cell RNA-Seq and ATAC-Seq data reveals regulatory toggles operating in native and iPS-derived retina
Anouk Georges, Haruko Takeda, Arnaud Lavergne, Michiko Mandai, Fanny Lepiemme, Latifa Karim, Loic Demeulenaere, Michael Schyns, Laurent Nguyen, Jean-Marie Rakic, Masayo Takahashi, Michel Georges
Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung revealed at single cell resolution
Racquel Domingo-Gonzalez, Fabio Zanini, Xibing Che, Min Liu, Robert C. Jones, Michael A. Swift, Stephen R. Quake, David N. Cornfield, Cristina M. Alvira
Single-cell transcriptome analysis reveals cell-cell communication and thyrocyte diversity in the zebrafish thyroid gland
Pierre Gillotay, Meghna P Shankar, Benoit Haerlingen, Sema Elif Eski, Macarena Pozo-Morales, Ines Garteizgogeascoa Suner, Susanne Reinhardt, Annekathrin Kraenkel, Juliane Blaesche, Andreas Petzold, Nikolay Ninov, Gokul Kesavan, Christian Lange, Michael Brand, Vincent Detours, Sabine Costagliola, Sumeet Pal Singh
Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition
Luis Enrique Cabrera Quio, Alexander Schleiffer, Karl Mechtler, Andrea Pauli
A role for KIF9 in male fertility
Ken Chen, Sang Yeon Cho, Yongwei Zhang, Amanda Beck, Jeffrey E. Segall
Sexual dimorphism in the meiotic requirement for PRDM9: a mammalian evolutionary safeguard
Natalie R Powers, Beth L Dumont, Chihiro Emori, Raman Akinyanju Lawal, Catherine Brunton, Ken Paigen, Mary Ann Handel, Ewelina Bolcun-Filas, Petko M Petkov, Tanmoy Bhattacharyya
Loss of dmrt1 restores female fates in the absence of cyp19a1a but not rbpms2
Shannon Romano, Odelya H. Kaufman, Florence L. Marlow
Single Cell Analysis Reveals Partial Reactivation of X-chromosome Instead of Chromosome-wide Dampening in Naïve Human Pluripotent Stem Cells
S Mandal, D Chandel, H Kaur, S Majumdar, M Arava, S Gayen
X-chromosome dosage compensation dynamics in human early embryos
Kevin Huang, Qiao Zeng, Yun Feng, Youjin Hu, Qin An, Taibo Li, Lian-Ju Qin, Jia-yin Liu, Zhigang Xue, Guoping Fan
Synergism between microRNA-124 and ELAVL3 drives neuronal gene upregulation during direct neuronal reprogramming of human fibroblasts
Ya-Lin Lu, Yangjian Liu, Andrew S. Yoo
Heterogeneity of Human Neuroepithelial Cells and Early Radial Glia
Ugomma C. Eze, Aparna Bhaduri, Tomasz J. Nowakowski, Arnold R. Kriegstein
Flexibility and constraint in preimplantation gene regulation in mouse
Colin C. Conine, Marina Krykbaeva, Lina Song, Robert C. Brewster, Nir Friedman, Oliver J. Rando
Changing the Waddington landscape to control mesendoderm competence
James R. Valcourt, Roya Huang, Sharmistha Kundu, Divya Venkatasubramanian, Robert E. Kingston, Sharad Ramanathan
| Stem cells, regeneration & disease modelling
Transcriptome analysis of somatic cell populations in the Drosophila testis links metabolism and stemness
Silvana Hof-Michel, Christian Bökel
Innate immune signalling drives loser cell elimination during stem cell competition in the Drosophila testis
Silvana Hof-Michel, Ljubinka Cigoja, Sabina Huhn, Christian Bökel
Dissecting Hes-centered transcriptional networks in neural stem cell maintenance and tumorigenesis in Drosophila
Srivathsa S. Magadi, Chrysanthi Voutyraki, Gerasimos Anagnostopoulos, Evanthia Zacharioudaki, Ioanna K. Poutakidou, Christina Efraimoglou, Margarita Stapountzi, Vasiliki Theodorou, Christoforos Nikolaou, Christos Delidakis
Progressive changes in hippocampal stem cell properties ensure lifelong neurogenesis
Lachlan Harris, Piero Rigo, Thomas Stiehl, Zachary Gaber, Sophie H. L. Austin, Maria del Mar Masdeu, Amelia Edwards, Noelia Urbán, Anna Marciniak-Czochra, François Guillemot
Subventricular zone adult mouse neural stem cells and human glioblastoma stem cells require insulin receptor for self-renewal
Shravanthi Chidambaram, Deborah Rothbard, Kaivalya Deshpande, Yvelanda Cajuste, Kristin M. Snyder, Eduardo Fajardo, Andras Fiser, Nikos Tapinos, Steven W. Levison, Teresa L. Wood
Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network
Miriam Pagin, Simone Giubbolini, Cristiana Barone, Gaia Sambruni, Yanfen Zhu, Sergio Ottolenghi, Chia-Lin Wei, Silvia K. Nicolis
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites
Jesse V Veenvliet, Adriano Bolondi, Helene Kretzmer, Leah Haut, Manuela Scholze-Wittler, Dennis Schifferl, Frederic Koch, Milena Pustet, Simon Heimann, Rene Buschow, Lars Wittler, Bernd Timmermann, Alexander Meissner, Bernhard G Herrmann
Defining totipotency using criteria of increasing stringency
Eszter Posfai, John Paul Schell, Adrian Janiszewski, Isidora Rovic, Alexander Murray, Brian Bradshaw, Tine Pardon, Mouna El Bakkali, Irene Talon, Natalie De Geest, Pankaj Kumar, San Kit To, Sophie Petropoulos, Andrea Jurisicova, Vincent Pasque, Fredrik Lanner, Janet Rossant
Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization
Irène Aksoy, Cloé Rognard, Anaïs Moulin, Guillaume Marcy, Etienne Masfaraud, Florence Wianny, Véronique Cortay, Angèle Bellemin-Ménard, Nathalie Doerflinger, Manon Dirheimer, Chloé Mayère, Cian Lynch, Olivier Raineteau, Thierry Joly, Colette Dehay, Manuel Serrano, Marielle Afanassieff, Pierre Savatier
Oxidative and non-oxidative active turnover of genomic methylcytosine in distinct pluripotent states
Fabio Spada, Sarah Schiffers, Angie Kirchner, Yingqian Zhang, Gautier Arista, Olesea Kosmatchev, Eva Korytiakova, René Rahimoff, Charlotte Ebert, Thomas Carell
Cathepsin K is required for maintenance and regeneration of lymphopoiesis in vivo
Renate Hausinger, Marianne Hackl, Ana Jardon-Alvarez, Miriam Kehr, Sandra Romero Marquez, Franziska Hettler, Christian Kehr, Sandra Grziwok, Christina Schreck, Christian Peschel, Rouzanna Istvanffy, Robert A.J. Oostendorp
Yolk sac erythromyeloid progenitors sustain erythropoiesis throughout embryonic life
Francisca Soares-da-Silva, Odile Burlen-Defranoux, Ramy Elsaid, Lorea Iturri, Laina Freyer, Odile Sismeiro, Perpétua Pinto-do-Ó, Elisa Gomez-Perdiguero, Ana Cumano
Endothelial mTOR maintains hematopoiesis during aging
Pradeep Ramalingam, Michael G. Poulos, Michael C. Gutkin, Lizabeth Katsnelson, Ana G. Freire, Elisa Lazzari, Jason M. Butler
Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA
Kai Wang, Ruei-Zeng Lin, Xuechong Hong, Alex H. Ng, Chin Nien Lee, Joseph Neumeyer, Gang Wang, Xi Wang, Minglin Ma, William T. Pu, George M. Church, Juan M. Melero-Martin
Robust Production of Uniform Human Cerebral Organoids from Pluripotent Stem Cells
A. Sivitilli, J.T. Gosio, B. Ghoshal, A. Evstratova, D. Trcka, P. Ghiasiighorveh, J. J. Hernandez, J. M. Beaulieu, J. L. Wrana, L. Attisano
Differentiation of human intestinal organoids with endogenous vascular endothelial cells
Emily M. Holloway, Joshua H. Wu, Michael Czerwinkski, Caden W. Sweet, Angeline Wu, Yu-Hwai Tsai, Sha Huang, Amy E. Stoddard, Meghan M. Capeling, Ian Glass, Jason R. Spence
Endothelial Cells stimulate proliferation of CD140a sorted human Glial Progenitor Cells and their specification towards astrocytic lineage
Asmita Dasgupta
Lipid availability influences the metabolic maturation of human pluripotent stem cell-derived cardiomyocytes
Hui Zhang, Mehmet G. Badur, Sean Spiering, Ajit Divakaruni, Noah E. Meurs, Michael S. Yu, Alexandre R. Colas, Anne N. Murphy, Mark Mercola, Christian M. Metallo
Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas
Thanh Hoang, Jie Wang, Patrick Boyd, Fang Wang, Clayton Santiago, Lizhi Jiang, Manuela Lahne, Sooyeon Yoo, Levi J. Todd, Cristian Saez, Casey Keuthan, Isabella Palazzo, Natalie Squires, Warren A. Campbell, Meng Jia, Fatemeh Rajaii, Trisha Parayil, Vickie Trinh, Dong Won Kim, Guohua Wang, John Ash, Andy J. Fischer, David R. Hyde, Jiang Qian, Seth Blackshaw
Canonical Wnt Signaling is Involved in Anterior Regeneration of the Annelid Aeolosoma viride
Cheng-Yi Chen, Wei-Ting Yueh, Jiun-Hong Chen
A regulatory program for initiation of Wnt signaling during posterior regeneration
Alyson N. Ramirez, Kaitlyn Loubet-Senear, Mansi Srivastava
Protrudin functions as a scaffold in the endoplasmic reticulum to support axon regeneration in the adult central nervous system
Veselina Petrova, Craig S. Pearson, James R. Tribble, Andrea G. Solano, Evan Reid, Pete A. Williams, Herbert M. Geller, Richard Eva, James W. Fawcett
Regenerated Interneurons Integrate Into Locomotor Circuitry Following Spinal Cord Injury
Deeptha Vasudevan, Yen-Chyi Liu, Joshua P. Barrios, Maya K. Wheeler, Adam D. Douglass, Richard I. Dorsky
Localized activation of ependymal progenitors induces EMT-mediated glial bridging after spinal cord injury
Lili Zhou, Brooke Burris, Ryan Mcadow, Mayssa H. Mokalled
A metabolic shift to glycolysis promotes zebrafish tail regeneration through TGF–β dependent dedifferentiation of notochord cells to form the blastema
Jason W. Sinclair, David R. Hoying, Erica Bresciani, Damian Dalle Nogare, Carli D. Needle, Weiwei Wu, Kevin Bishop, Abdel G. Elkahloun, Ajay Chitnis, Paul Liu, Shawn M. Burgess
Suppression of Inflammation Delays Hair Cell Regeneration and Functional Recovery Following Lateral Line Damage in Zebrafish Larvae
Ru Zhang, Xiao-Peng Liu, Ya-Juan Li, Ming Wang, Lin Chen, Bing Hu
β-catenin Signaling Regulates Cell Fate Decisions at the Transition Zone of the Chondro-Osseous Junction During Fracture Healing
Sarah Anne Wong, Diane Hu, Tiffany Shao, Erene Niemi, Emilie Barruet, Blanca M Morales, Omid Boozarpour, Theodore Miclau, Edward C Hsiao, Mary Nakamura, Chelsea S Bahney, Ralph S Marcucio
Fidgetin-like 2 is a novel negative regulator of axonal growth and can be targeted to promote functional nerve regeneration after injury
Lisa Baker, Moses Tar, Guillermo Villegas, Rabab Charafeddine, Adam Kramer, Olga Vafaeva, Parimala Nacharaju, Joel Friedman, Kelvin P. Davies, David J. Sharp
Human patient SFPQ homozygous mutation is found deleterious for brain and motor development in a zebrafish model
Patricia M Gordon, Stephanie Efthymiou, Vincenzo Salpietro, Triona Fielding, Eugenia Borgione, Carmela Scuderi, Henry Houlden, Corinne Houart
Genes critical for development and differentiation of dopaminergic neurons are downregulated in Parkinson’s disease
Aditi Verma, Etienne C. Hirsch, Vijayalakshmi Ravindranath
Brainstem development requires galactosylceramidase and is critical for the pathogenesis of Krabbe Disease
Nadav I. Weinstock, Conlan Kreher, Jacob Favret, Ernesto Bongarzone, Lawrence Wrabetz, M. Laura Feltri, Daesung Shin
Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes
Elisabeth Mangiameli, Anna Cecchele, Francesco Morena, Francesca Sanvito, Vittoria Matafora, Lucrezia Della Volpe, Daniela Gnani, Marianna Paulis, Lucia Susani, Sabata Martino, Raffaella Di Micco, Angela Bachi, Angela Gritti
Large-scale Phenotypic Drug Screen Identifies Neuroprotectants in Zebrafish and Mouse Models of Retinitis Pigmentosa
Liyun Zhang, Conan Chen, Jie Fu, Brendan Lilley, Cynthia Berlinicke, Baranda Hansen, Ding Ding, Guohua Wang, Tao Wang, Daniel Shou, Ying Ye, Meera T. Saxena, Kelsi R. Hall, Abigail V. Sharrock, Carlene Brandon, Joong Sup Shim, Justin Hanes, Hongkai Ji, Jun O. Liu, Jiang Qian, David F. Ackerley, Baerbel Rohrer, Donald J. Zack, Jeff S. Mumm
| Plant development
Subtilase activity in the intrusive cells mediates haustorium maturation in parasitic plants
Satoshi Ogawa, Takanori Wakatake, Thomas Spallek, Juliane K Ishida, Ryosuke Sano, Tetsuya Kurata, Taku Demura, Satoko Yoshida, Yasunori Ichihashi, Andreas Schaller, Ken Shirasu
Host-parasite tissue adhesion by a secreted type of β-1,4-glucanase in the parasitic plant Phtheirospermum japonicum
Ken-ichi Kurotani, Takanori Wakatake, Yasunori Ichihashi, Koji Okayasu, Yu Sawai, Satoshi Ogawa, Takamasa Suzuki, Ken Shirasu, Michitaka Notaguchi
Cell–cell adhesion in plant grafting is facilitated by β-1,4-glucanases
Michitaka Notaguchi, Ken-ichi Kurotani, Yoshikatsu Sato, Ryo Tabata, Yaichi Kawakatsu, Koji Okayasu, Yu Sawai, Ryo Okada, Masashi Asahina, Yasunori Ichihashi, Ken Shirasu, Takamasa Suzuki, Masaki Niwa, Tetsuya Higashiyama
Spindle position dictates division site during asymmetric cell division in moss
Elena Kozgunova, Mari W. Yoshida, Gohta Goshima
Light controls de novo adventitious root regeneration by modulating jasmonate and cytokinin homeostasis in Norway spruce hypocotyls
Sanaria Alallaq, Alok Ranjan, Federica Brunoni, Ondřej Novák, Abdellah Lakehal, Catherine Bellini
Developmental atlas of white lupin cluster roots
Cecilia Gallardo, Barbara Hufnagel, Alexandre Soriano, Fanchon Divol, Laurence Marques, Patrick Doumas, Benjamin Peret
Ppd-H1 integrates drought stress signals to control spike development and flowering time in barley
Leonard Gol, Einar B. Haraldsson, Maria von Korff
FLOWERING LOCUS T4 (HvFT4) delays flowering and decreases floret fertility in barley
Rebekka Pieper, Filipa Tome, Maria von Korff Schmising
WOX9 functions antagonistic to STF and LAM1 to regulate leaf blade expansion in Medicago truncatula and Nicotiana sylvestris
Tezera W. Wolabu, Hui Wang, Dimiru Tadesse, Fei Zhang, Marjan Behzadirad, Varvara E. Tvorogova, Haggagi Abdelmageed, Ye Liu, Naichong Chen, Jianghua Chen, Randy D. Allen, Million Tadege
Dynamic localization of SPO11-1 and conformational changes of meiotic axial elements during recombination initiation of maize meiosis
Jia-Chi Ku, Arnaud Ronceret, Inna Golubovskaya, Ding Hua Lee, Chiting Wang, Ljudmilla Timofejeva, Yu-Hsin Kao, Ana Karen Gomez Angoa, Karl Kremling, Rosalind Williams-Carrier, Robert Meeley, Alice Barkan, W. Zacheus Cande, Chung-Ju Rachel Wang
The Hoja loca1 Mutant and AUX/1 IAA Function in Maize
Annis Richardson, Aaron Sluis, Sarah Hake
RNA editing in inflorescences of wild grapevine unveils association to sex and development
Miguel J. N. Ramos, David Faísca-Silva, João L. Coito, Jorge Cunha, Helena Gomes Silva, Wanda Viegas, M. Manuela R. Costa, Sara Amâncio, Margarida Rocheta
Evolutionary variation in MADS-box dimerization affects floral development and protein degradation dynamics
Maria Jazmin Abraham-Juarez, Amanda Schrager-Lavelle, Jarrett Man, Clinton Whipple, Pubudu Handakumbura, Courtney Babbitt, Madelaine Bartlett
Intragenic Complementation of Cellulose Synthase-Like D1 alleles in Root Hair Development
Bogumil J. Karas, Loretta Ross, Mara Novero, Lisa Amyot, Sayaka Inada, Michiharu Nakano, Tatsuya Sakai, Sushei Sato, Jeremy Dale Murray, Paola Bonfante, Krzysztof Szczyglowski
The transcription and export complex THO/TREX contributes to transcription termination in plants
Ghazanfar Abbas Khan, Jules Deforges, Rodrigo S. Reis, Yi-Fang Hsieh, Jonatan Montpetit, Wojciech Antosz, Luca Santuari, Christian S Hardtke, Klaus Grasser, Yves Poirier
Timing of organ initiation is crucial for robust organ size
Mingyuan Zhu, Weiwei Chen, Vincent Mirabet, Lilan Hong, Simone Bovio, Soeren Strauss, Erich M. Schwarz, Satoru Tsugawa, Zhou Wang, Richard S. Smith, Chun-Biu Li, Olivier Hamant, Arezki Boudaoud, Adrienne H. K. Roeder
Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL
Jeremy Sloan, Jana Hankenjos, Michael Gebert, Olga Ermakova, Andrea Gumiero, Gunter Stier, Klemens Wild, Irmgard Sinning, Jan U. Lohmann
Cell wall remodeling and vesicle trafficking mediate the root clock in Arabidopsis
Guy Wachsman, Jingyuan Zhang, Miguel A. Moreno-Risueno, Charles T. Anderson, Philip N. Benfey
Disruption of CYCLOPHILIN 38 function reveals a photosynthesis-dependent systemic signal controlling lateral root emergence
Lina Duan, Juan Manuel Pérez-Ruiz, Francisco Javier Cejudo, José R. Dinneny
Reshaping of the Arabidopsis thaliana proteome landscape and co-regulation of proteins in development and immunity
Mona Bassal, Petra Majovsky, Domenika Thieme, Tobias Herr, Mohammad Abukhalaf, Mohamed Ayash, MHD Rami Al Shweiki, Carsten Proksch, Ali Hmedat, Jörg Ziegler, Steffan Neumann, Wolfgang Hoehenwarter
Noxious effects of cell surface display glutamate sensors on plant growth and development
Vanessa Castro-Rodríguez, Thomas J. Kleist, Nicoline M. Gappel, Sakiko Okumoto, Mackenzie Machado, Tom Denyer, Marja C. P. Timmermans, Wolf B. Frommer, Michael M. Wudick
Two groups of Arabidopsis receptor kinases preferentially regulate the growth of intraspecies pollen tubes in the female reproductive tract
Hyun Kyung Lee, Daphne R. Goring
CYCA3;4 Is a Post-Prophase Target of the APC/CCCS52A2 E3-Ligase Controlling Formative Cell Divisions in Arabidopsis
Alex Willems, Jefri Heyman, Thomas Eekhout, Ignacio Achon, Jose Antonio Pedroza-Garcia, Tingting Zhu, Lei Li, Ilse Vercauteren, Hilde Van den Daele, Brigitte van de Cotte, Ive De Smet, Lieven De Veylder
Stigma Receptivity is controlled by Functionally Redundant MAPK Pathway Components in Arabidopsis
Muhammad Jamshed, Subramanian Sankaranarayanan, Kumar Abhinandan, Marcus A. Samuel
Structure-function analysis of Arabidopsis TOPLESS reveals conservation of repression mechanisms across eukaryotes
Alexander R. Leydon, Wei Wang, Samuel Juarez-Solis, Joseph E. Zemke, Mollye L. Zahler, Ning Zheng, Jennifer L. Nemhauser
Altered stomatal patterning accompanies a trichome dimorphism in a natural population of Arabidopsis
Noriane M. L. Simon, Jiro Sugisaka, Mie N. Honjo, Sverre Aarseth Tunstad, George Tunna, Hiroshi Kudoh, Antony N. Dodd
A new role for histone demethylases in the maintenance of plant genome integrity
Javier Antunez-Sanchez, Matthew Naish, Juan Sebastian Ramirez-Prado, Sho Ohno, Ying Huang, Alexander Dawson, Deborah Manza-Mianza, Federico Ariel, Cecile Raynaud, Anjar Wilbowo, Josquin Daron, Minako Ueda, David Latrasse, R. Keith Slotkin, Detlef Weigel, Moussa Benhamed, Jose Gutierrez-Marcos
In Arabidopsis, low blue light enhances phototropism by releasing cryptochrome 1-mediated inhibition of PIF4 expression
Alessandra Boccaccini, Martina Legris, Johanna Krahmer, Laure Allenbach-Petrolati, Anupama Goyal, Carlos Galvan-Ampudia, Teva Vernoux, Elisabeth Karayekov, Jorge Casal, Christian Fankhauser
External mechanical cues reveal core molecular pathway behind tissue bending in plants
Anirban Baral, Emily Morris, Bibek Aryal, Kristoffer Jonsson, Stéphane Verger, Tongda Xu, Malcolm Bennett, Olivier Hamant, Rishikesh P. Bhalerao
Nucleo-plastidic PAP8/pTAC6 couples chloroplast formation with photomorphogenesis
Monique Liebers, François-Xavier Gillet, Abir Israel, Kevin Pounot, Louise Chambon, Maha Chieb, Fabien Chevalier, Rémi Ruedas, Adrien Favier, Pierre Gans, Elisabetta Boeri Erba, David Cobessi, Thomas Pfannschmidt, Robert Blanvillain
Establishment of Proximity-dependent Biotinylation Approaches in Different Plant Model Systems
Deepanksha Arora, Nikolaj B. Abel, Chen Liu, Petra Van Damme, Klaas Yperman, Lam Dai Vu, Jie Wang, Anna Tornkvist, Francis Impens, Barbara Korbei, Dominique Eeckhout, Jelle Van Leene, Alain Goossens, Geert De Jaeger, Thomas Ott, Panagiotis Moschou, Daniël Van Damme
Evo-devo & evo
Embryo-like features in developing Bacillus subtilis biofilms
Momir Futo, Luka Opašić, Sara Koska, Nina Čorak, Tin Široki, Vaishnavi Ravikumar, Annika Thorsell, Domagoj Kifer, Mirjana Domazet-Lošo, Kristian Vlahoviček, Ivan Mijaković, Tomislav Domazet-Lošo
Histone modifications during the life cycle of the brown alga Ectocarpus
Simon Bourdareau, Leila Tirichine, Bérangère Lombard, Damarys Loew, Delphine Scornet, Susana M. Coelho, J. Mark Cock
Embryogenesis, polyembryony, and settlement in the gorgonian Plexaura homomalla
Christopher D. Wells, Kaitlyn J. Tonra, Howard R. Lasker
ebony affects pigmentation divergence and cuticular hydrocarbons in Drosophila americana and D. novamexicana
Abigail M. Lamb, Zinan Wang, Patricia Simmer, Henry Chung, Patricia J. Wittkopp
Multiple loci linked to inversions are associated with eye size variation in species of the Drosophila virilis phylad
Micael Reis, Gordon Wiegleb, Julien Claude, Rodrigo Lata, Britta Horchler, Ngoc-Thuy Ha, Christian Reimer, Cristina P. Vieira, Jorge Vieira, Nico Posnien
Feeding-dependent tentacle development in the sea anemone Nematostella vectensis
Aissam Ikmi, Petrus J. Steenbergen, Marie Anzo, Mason R. McMullen, Anniek Stokkermans, Lacey R. Ellington, Matthew C. Gibson
The polymorphism of Hydra microsatellite sequences provides strain-specific signatures
Quentin Schenkelaars, Diego Perez-Cortez, Chrystelle Perruchoud, Brigitte Galliot
Single cell chromatin accessibility of the developmental cephalochordate
Dongsheng Chen, Zhen Huang, Xiangning Ding, Zaoxu Xu, Jixing Zhong, Langchao Liang, Luohao Xu, Chaochao Cai, Haoyu Wang, Jiaying Qiu, Jiacheng Zhu, Xiaoling Wang, Rong Xiang, Weiying Wu, Peiwen Ding, Feiyue Wang, Qikai Feng, Si Zhou, Yuting Yuan, Wendi Wu, Yanan Yan, Yitao Zhou, Duo Chen, Guang Li, Shida Zhu, Fang Chen, Qiujin Zhang, Jihong Wu, Xun Xu
Ontogenetic and static allometry of hind femur length in the cricket Gryllus bimaculatus (Orthoptera: Gryllidae) with implications for evo-devo of morphological scaling
Jakke Sameli Neiro
Plasticity and Artificial Selection for Developmental Mode in a Poecilogonous Sea Slug
Serena A. Caplins
Asymmetric second generation genomic incompatibility in interspecific crosses between Ciona robusta and Ciona intestinalis
Naoyuki Ohta, Nicole Kaplan, James Tyler Ng, Basile Jules Gravez, Lionel Christiaen
Shift in worker physiology and gene expression pattern from reproductive to diapause-like with colony age in the bumble bee Bombus impatiens
Erin D. Treanore, Jacklyn M. Kiner, Mackenzie E. Kerner, Etya Amsalem
Vitellogenin expression in the ovaries of adult honeybee workers provides insights into the evolution of reproductive and social traits
Carlos Antônio Mendes Cardoso-Júnior, Benjamin P. Oldroyd, Isobel Ronai
Are there systematic biases in RNA-seq data analysis? A case study for Amphimedon queenslandica sponge as a model object
Sergey Feranchuk
Changes in gene expression during female reproductive development in a colour polymorphic insect
B. Willink, M. C. Duryea, C. Wheat, E. I. Svensson
Rapid speciation of cichlids fishes may be explained by evolutionary divergence of novel open reading frames
Shraddha Puntambekar, Rachel Newhouse, Jaime San Miguel Navas, Ruchi Chauhan, Grégoire Vernaz, Thomas Willis, Matthew T. Wayland, Yagnesh Urmania, Eric A. Miska, Sudhakaran Prabakaran
Molecular evolution and developmental expression of melanin pathway genes in Lepidoptera
Muktai Kuwalekar, Riddhi Deshmukh, Ajay Padvi, Krushnamegh Kunte
Evidence from Amphioxus for acquisition of alternative mRNA splicing of NCoR corepressor after its duplication and divergence during vertebrate evolution
Martin L. Privalsky
Conspicuous candidate alleles point to cis-regulatory divergence underlying rapidly evolving craniofacial phenotypes
Joseph A. McGirr, Christopher H. Martin
Recapitulating evolutionary divergence in a single cis-regulatory element is sufficient to cause expression changes of the lens gene Tdrd7
Juliana G. Roscito, Kaushikaram Subramanian, Ronald Naumann, Mihail Sarov, Anna Shevchenko, Aliona Bogdanova, Thomas Kurth, Leo Foerster, Moritz Kreysing, Michael Hiller
Cell biology
Extracellular domains of E-cadherin determine key mechanical phenotypes of an epithelium through cell- and non-cell-autonomous outside-in signalling
D.M.K. Aladin, Y.S. Chu, R.C. Robinson, S. Dufour, V. Viasnoff, N. Borghi, J.P. Thiery
Laminin-511 and α6 Integrins Regulate the Expression of CXCR4 to Promote Endothelial Morphogenesis
Hao Xu, Kevin Pumiglia, Susan E. LaFlamme
Transit-amplifying cells coordinate changes in intestinal epithelial cell-type composition
Laura E. Sanman, Ina W. Chen, Jake M. Bieber, Veronica Steri, Byron Hann, Lani F. Wu, Steven J. Altschuler
Phosphorylation of the Anaphase Promoting Complex activator CDH1/FZR regulates the transition from Meiosis I to Meiosis II in mouse male germ cell
Nobuhiro Tanno, Shinji Kuninaka, Sayoko Fujimura, Kaho Okamura, Kazumasa Takemoto, Kimi Araki, Masatake Araki, Hideyuki Saya, Kei-ichiro Ishiguro
Nestin selectively facilitates the phosphorylation of the Lissencephaly-linked protein doublecortin (DCX) by cdk5/p35 to regulate growth cone morphology and Sema3a sensitivity in developing neurons
Christopher J. Bott, Lloyd P. McMahon, Jason M. Keil, Chan Choo Yap, Kenneth Y. Kwan, Bettina Winckler
Midbody remnant inheritance is regulated by the ESCRT subunit CHMP4C
Javier Casares-Arias, María Ujué Gonzalez, Alvaro San Paulo, Leandro N. Ventimiglia, Jessica B. A. Sadler, David G. Miguez, Leticia Labat-de-Hoz, Armando Rubio-Ramos, Laura Rangel, Miguel Bernabé-Rubio, Jaime Fernández-Barrera, Isabel Correas, Juan Martín-Serrano, Miguel A. Alonso
Septin Roles and Mechanisms in Organization of Endothelial Cell Junctions
Joanna Kim, John A. Cooper
SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation
Linh Le, Iliana E. Escobar, Tina Ho, Ariel J. Lefkovith, Emily Latteri, Megan K. Dennis, Kirk D. Haltaufderhyde, Elena V. Sviderskaya, Dorothy C. Bennett, Elena Oancea, Michael S. Marks
Biophysical forces rewire cell metabolism to guide microtubule-dependent cell mechanics
Stephanie Torrino, Stephane Audebert, Ilyes Belhadj, Caroline Lacoux, Sabrina Pisano, Sophie Abélanet, Frederic Brau, Stephen Y. Chan, Bernard Mari, William M Oldham, Thomas Bertero
Conserved epigenetic regulatory logic infers genes governing cell identity
Woo Jun Shim, Enakshi Sinniah, Jun Xu, Burcu Vitrinel, Michael Alexanian, Gaia Andreoletti, Sophie Shen, Brad Balderson, Guangdun Peng, Naihe Jing, Yuliangzi Sun, Yuliang Wang, Patrick P L Tam, Aaron Smith, Michael Piper, Lionel Christiaen, Quan Nguyen, Mikael Bodén, Nathan J. Palpant
Functionally non-redundant paralogs spe-47 and spe-50 encode FB-MO associated proteins and interact with him-8
Jessica N. Clark, Gaurav Prajapati, Fermina Aldaco, Thomas J. Sokolich, Steven Keung, Sarojani Austin, Ángel A. Valdés, Craig W. LaMunyon
Growth-dependent activation of protein kinases suggests a mechanism for measuring cell growth
Akshi Jasani, Tiffany Huynh, Douglas R. Kellogg
Modelling
A unified mechanism for spatiotemporal patterns in somitogenesis
Chandrashekar Kuyyamudi, Shakti N. Menon, Sitabhra Sinha
A novel mathematical model of heterogeneous cell proliferation
Sean T. Vittadello, Scott W. McCue, Gency Gunasingh, Nikolas K. Haass, Matthew J. Simpson
Multiscale mechanical model for cell division orientation in developing biological systems
B. Leggio, J. Laussu, E. Faure, P. Lemaire, C. Godin
Theoretical analysis of neural crest cell migration
Hamid Khataee, Andras Czirok, Zoltan Neufeld
PDE models of adder mechanisms in cellular proliferation
Mingtao Xia, Chris D. Greenman, Tom Chou
A bleb initiation model for chemotaxis suggests a role for myosin II clusters and cortex rupture
E.O Asante-Asamani, Daniel Grange, Devarshi Rawal, Zully Santiago, Derrick Brazill, John Loustau
Tools & resources
Two new genetically modified mouse alleles labeling distinct phases of retinal ganglion cell development by fluorescent proteins
Yichen Ge, Fuguo Wu, Mobin Cheng, Xiuqian Mu
Novel mosaic mice with diverse applications
Yuxin Chen, Shaoshuai Mao, Bo Liu, Zhengyu Jing, Ying Zang, Jing Xia, Jianlong Sun, Tian Chi
A systematic, label-free method for identifying RNA-associated proteins in vivo provides insights into vertebrate ciliary beating
Kevin Drew, Chanjae Lee, Rachael M. Cox, Vy Dang, Caitlin C. Devitt, Ophelia Papoulas, Ryan L. Huizar, Edward M. Marcotte, John B. Wallingford
smiFISH and embryo segmentation for single-cell multi-gene RNA quantification in arthropods
Llilians Calvo, Matthew Ronshaugen, Tom Pettini
Characterization of fluorescent proteins with intramolecular photostabilization
Sarah S. Henrikus, Konstantinos Tassis, Lei Zhang, Jasper H. M. van der Velde, Christian Gebhardt, Andreas Herrmann, Gregor Jung, Thorben Cordes
A pancreas specific Ptf1a-driven Cre mouse line causes paternally transmitted germline recombination
Derya Kabacaoglu, Marina Lesina, Hana Algül
Content and performance of the MiniMUGA genotyping array, a new tool to improve rigor and reproducibility in mouse research
John Sebastian Sigmon, Matthew W Blanchard, Ralph S Baric, Timothy A Bell, Jennifer Brennan, Gudrun A Brockmann, A Wesley Burks, J Mauro Calabrese, Kathleen M Caron, Richard E Cheney, Dominic Ciavatta, Frank Conlon, David B Darr, James Faber, Craig Franklin, Timothy R Gershon, Lisa Gralinski, Bin Gu, Christiann H Gaines, Robert S Hagan, Ernest G Heimsath, Mark T Heise, Pablo Hock, Folami Ideraabdullah, J. Charles Jennette, Tal Kafri, Anwica Kashfeen, Samir Kelada, Mike Kulis, Vivek Kumar, Colton Linnertz, Alessandra Livraghi-Butrico, Kent Lloyd, Richard Loeser, Cathleen Lutz, Rachel M Lynch, Terry Magnuson, Glenn K Matsushima, Rachel McMullan, Darla Miller, Karen L Mohlke, Sheryl S Moy, Caroline Murphy, Maya Najarian, Lori O’Brien, Abraham A Palmer, Benjamin D Philpot, Scott Randell, Laura Reinholdt, Yuyu Ren, Steve Rockwood, Allison R Rogala, Avani Saraswatula, Christopher M Sasseti, Jonathan C Schisler, Sarah A Schoenrock, Ginger Shaw, John R Shorter, Clare M Smith, Celine L St. Pierre, Lisa M Tarantino, David W Threadgill, William Valdar, Barbara J Vilen, Keegan Wardwell, Jason K Whitmire, Lucy Williams, Mark Zylka, Martin T Ferris, Leonard McMillan, Fernando Pardo-Manuel de Villena
Optimization of mouse embryonic stem cell culture for organoid and chimeric mice production
Cécilie Martin-Lemaitre, Yara Alcheikh, Ronald Naumann, Alf Honigmann
RhoBAST – a rhodamine-binding aptamer for super-resolution RNA imaging
Murat Sunbul, Jens Lackner, Annabell Martin, Daniel Englert, Benjamin Hacene, Karin Nienhaus, G. Ulrich Nienhaus, Andres Jäschke
Split-TurboID enables contact-dependent proximity labeling in cells
Kelvin F. Cho, Tess C. Branon, Sanjana Rajeev, Tanya Svinkina, Namrata D. Udeshi, Themis Thoudam, Chulhwan Kwak, Hyun-Woo Rhee, In-Kyu Lee, Steven A. Carr, Alice Y. Ting
Left-handed DNA-PAINT for improved superresolution imaging in the nucleus.
Hylkje Geertsema, Giulia Aimola, Valentin Fabricius, Jens Peter Fuerste, Benedikt Kaufer, Helge Ewers
Research practice & education
Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature
Clarissa F. D. Carneiro, Victor G. S. Queiroz, Thiago C. Moulin, Carlos A. M. Carvalho, Clarissa B. Haas, Danielle Rayêe, David E. Henshall, Evandro A. De-Souza, Felippe E. Amorim, Flávia Z. Boos, Gerson D. Guercio, Igor R. Costa, Karina L. Hajdu, Lieve van Egmond, Martin Modrák, Pedro B. Tan, Richard J. Abdill, Steven J. Burgess, Sylvia F. S. Guerra, Vanessa T. Bortoluzzi, Olavo B. Amaral
Quantifying and contextualizing the impact of bioRxiv preprints through automated social media audience segmentation
Jedidiah Carlson, Kelley Harris
A comparative analysis reveals irreproducibility in searches of scientific literature
Gábor Pozsgai, Gábor L. Lövei, Liette Vasseur, Geoff Gurr, Péter Batáry, János Korponai, Nick A. Littlewood, Jian Liu, Arnold Móra, John Obrycki, Olivia Reynolds, Jenni A. Stockan, Heather VanVolkenburg, Jie Zhang, Wenwu Zhou, Minsheng You
The natural selection of good science
Alexander J. Stewart, Joshua B. Plotkin
Rigor and Transparency Index, a new metric of quality for assessing biological and medical science methods
Joe Menke, Martijn Roelandse, Burak Ozyurt, Maryann Martone, Anita Bandrowski
Sociality enhances survival in science, especially for female researchers
Jessica E.M. van der Wal, Rose Thorogood, Nicholas P.C. Horrocks
Methods for Running a Successful Women-in-STEM Organization on an Academic Campus
Deborah D. Rupert, Alexandra C. Nowlan, Oliver H. Tam, Molly Gale Hammell
Sorry, we’re open: Golden Open Access and inequality in the natural sciences
Russell J Gray
Who reviews for predatory journals? A study on reviewer characteristics
Anna Severin, Michaela Strinzel, Matthias Egger, Marc Domingo, Tiago Barros
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