The Center for Neurogastroenterology at The Johns Hopkins University, Baltimore MD is looking for multiple motivated and driven post-doctoral fellows to study the innervation of the gastrointestinal tract at health and in various gastrointestinal diseases of dysmotility and chronic pain.
The Center consists of basic, translational and clinical scientists that collaborate heavily with engineering, drug development, and data science labs at Hopkins and around the world. We are dedicated to understanding the molecular and cellular changes to intrinsic and extrinsic neurons of the gastrointestinal tract and its investigators work in a team-based manner to study the basic, translational, and clinical biology of chronic gastrointestinal pain and intestinal motility disorders.
The successful applicants will work collaboratively with research teams in the Center to establish the anatomical and functional neurocircuitry of the organs of the gastrointestinal tract. The research will focus on elucidating the key disease-associated molecular and circuit level changes accrued in the neuronal circuitry that have pathological functional outcomes.
The successful applicants will work on projects that aim to (a) use various imaging
platforms and strategies, including confocal microscopy, multi-photon microscopy and light-sheet microscopy, to interrogate and trace specific neural circuits that innervate the gastrointestinal tract at health and in various gastrointestinal diseases; and (b) study in vivo and ex vivo physiology of the gastrointestinal tract and its neuronal circuitry in novel animal models by performing CRISPR-based gene modifications in specific cell types. In addition, the fellows will also test the effect of novel therapeutic strategies on the normalization of pathological molecular, cellular, and circuit level changes in animal models of disease.
Candidates should have a PhD in Cellular Biology, Neuroscience, Systems Biology with significant experience in either Microscopy, CRISPR biology or Physiology
Interested candidates should send their CV along with their three references to
Aimee Stone at firstname.lastname@example.org