the community site for and by developmental biologists

About: DMM

Biography:
Disease Models & Mechanisms is a peer-reviewed, Open Access journal focusing on the use of model organisms and other basic science approaches to better understand, diagnose and treat human disease. The journal aims to promote communication between basic researchers, translational researchers and clinicians.
Website:
http://dmm.biologists.org/

Posts by DMM:

New DMM Collection focused on Neurodegenerative Diseases

Posted by on May 3rd, 2017

A growing aging population means that age-dependent neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease and amyotrophic lateral sclerosis are affecting increasing numbers of people, making research into these diseases more important than ever. As a crucial resource for researchers and to showcase the vital research being done in the field, Disease Models[…]

Intern for Disease Models & Mechanisms

Posted by on November 8th, 2016

  DMM is looking for an enthusiastic intern who wishes to gain experience in science publishing, including writing press releases, contributing to our social media activities, and supporting our Reviews Editor with commissioned articles. The internship is envisaged to last for 9 months at a salary of £20,000 per annum pro rata. Our interns have[…]

Spotlight on Rat: Translational Impact – a new DMM Special Collection

Posted by on October 18th, 2016

Disease Models & Mechanisms is pleased to announce the launch of a new Special Collection named Spotlight on Rat: Translational Impact. The rat is a key model for basic and preclinical studies of physiology, pharmacology, toxicology and neuroscience, underlining its importance in studies of human disease. There are many reasons for its suitability as a[…]

Seeking out the sweet spot in cancer therapeutics: an interview with Lewis Cantley

Posted by on September 23rd, 2016

  “…had you told me when I was 25 years old that I would be the director of a cancer center I would have been incredulous, given that I was totally into chemistry”   This is an extract from an interview that originally appeared in Disease Models and Mechanisms (available here Open Access) Paraminder Dhillon,[…]

Intern for Disease Models and Mechanisms

Posted by on September 19th, 2016

DMM is looking for an enthusiastic intern who wishes to gain experience in science publishing, including writing press releases, contributing to our social media activities, and supporting our Reviews Editor with commissioned articles. The internship is envisaged to last for up to 1 year at a salary of £15,000 p.a. Our interns have a great[…]

Reproducibility: a pathological perspective

Posted by on June 20th, 2016

” the ability to reproduce experimental findings remains essential for the forward movement of science and the application of laboratory findings to the clinic”   This is an extract from a Special Article article that originally appeared in Disease Models and Mechanisms (available here Open Access) Paul Schofield, Jerrold Ward, John P. Sundberg   Reproducibility of data from[…]

Call for Papers: a Special Collection on Neurodegenerative Diseases

Posted by on May 31st, 2016

Disease Models & Mechanisms invites you to submit original research for consideration for an upcoming Special Collection ‘Neurodegeneration: From Models to Mechanisms to Therapies‘. This ongoing collection will focus on mechanistic insights into neurodegenerative diseases using model systems, with an emphasis on key translational advances made in recent years. This collection will be launched with[…]

Big data: challenges and opportunities

Posted by on May 11th, 2016

“With great power comes great responsibility” In recent years, next-generation-sequencing approaches have churned out a huge amount of ‘big data’ – a wealth of digital information that could one day have a powerful impact on biomedical research. Recognising the potential of big data to improve our understanding of human health and disease, the NIH partnered[…]

Insights into the pathogenic role of UVRAG in intestinal dysplasia

Posted by on May 4th, 2016

This post highlights the approach and findings of a new research article published in Disease Models & Mechanisms: ‘Stem cell-specific endocytic degradation defects lead to intestinal dysplasia in Drosophila’. This feature was written by Elan Strange as part of a graduate level seminar at The University of Alabama (taught by DMM Editorial Board member, Prof.[…]

Untangling developmentally programmed obesity: role of the serotonin system

Posted by on April 27th, 2016

This post highlights the approach and findings of a new research article published in Disease Models and Mechanisms (DMM): ‘5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats’. This feature was written by Richard Seeber as part of a graduate level seminar at The University of Alabama (taught by DMM Editorial Board[…]