The community site for and by
developmental and stem cell biologists

Behind the paper stories

Behind the paper stories

Every paper has a story behind it, and we regularly commission scientists to tell theirs. In this collection you’ll discover the highs and the lows, the chance encounters and life changing discoveries from the breadth of developmental biology and stem cell research.

Recent posts

Behind the paper: “Recording morphogen signals reveals origins of gastruloid symmetry breaking”

Posted by , on 17 January 2025

Stem cell models as laboratories to study self-organization My road from physics to developmental biology began in a journal club during my PhD in Adam Cohen’s lab at Harvard. We …

Winding road to the cambial stem cells

Posted by , on 13 January 2025

In plants, the vascular cambium, a bifacial stem cell niche, drives wood formation by generating the xylem on one side and the phloem on the other. In this post, Ari …

Behind the paper: “Temporal variability and cell mechanics control robustness in mammalian embryogenesis”

Posted by , on 15 December 2024

The massive presence of disorder and variability challenges the traditional metaphor of the developmental process as a perfectly executed program leading to precise mechanisms at every level [1,2]. Yet, the …

Don’t eat me!!

Posted by , on 15 November 2024

When I joined the Zon lab in June 2021, my mentor, Leonard Zon, shared an insightful piece of advice: “A good project always has two questions, one you can answer …

Behind the paper: A transcriptomic hourglass in brown algae

Posted by , on 12 November 2024

Brown algae are a group of complex multicellular eukaryotes, unrelated to animals, plants and fungi. It follows that brown algae evolved the process of multicellular development independently, offering a unique …

Behind the paper: Highlighting skeleton-producing cells during the development of a pentaradial animal

Posted by , on 24 September 2024

Read the story behind the paper “Localization and origins of juvenile skeletogenic cells in the sea urchin Lytechinus pictus” from Heidi Tate.

Making a map: exploring the origins of the shoulder and neck

Posted by , on 18 September 2024

Read the story behind the paper “Multiple embryonic sources converge to form the pectoral girdle skeleton in zebrafish” from first author Shunya Kuroda.

A short rant on the present and future of developmental biology

Posted by , on 11 September 2024

Observing a cluster of migrating cells or a developing embryo through the lens of a microscope can be a visceral experience; one is struck by the ephemeral beauty, layered complexity, …

“If you notice something unusual in your experiments, don’t just throw it away!”

Read Laura Pellegrini’s piece on choroid plexus organoids 

Do you have a story to tell? We can give comments on drafts and any level of editing you want, and we particularly encourage contributions from researchers for whom English is not their first language.

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Our full archive going back to 2010 is filterable by category, tag and date.

Updated on 21 August 2024