the community site for and by developmental biologists

Sensing and making sense of clonal fragmentation in developing tissues

Posted by on March 23rd, 2018

Steffen Rulands and Benjamin Simons A discussion of our recent paper: Rulands S et al., Universality of clone dynamics during tissue development. Nature Physics | doi:10.1038/s41567-018-0055-6   Often, the most enjoyable research projects are the ones that were never planned; and so it was with the current study.   In developmental biology, genetic lineage tracing[…]

Mechanical cues as developmental pacers that orchestrate morphogenesis

Posted by on March 22nd, 2018

In these lines I share with you some details of our recently published Nature paper. I will comment how this project was started and details which are not included in the manuscript. Finally, I will briefly comment on some questions we are working on today and others we believe are worth addressing in the future.[…]

From stem cells to human development: meeting reporter competition

Posted by on March 22nd, 2018

In September, Development is hosting the third of its highly successful series of meetings focusing on human developmental biology. Held in the Wotton House estate near Dorking in Surrey and organised by Paola Arlotta, Ali Brivanlou, Olivier Pourquié and Jason Spence, the meeting will cover the latest developments and future prospects for this rapidly evolving field (you[…]

Postdoctoral Fellow Positions in Development and Regenerative Medicine at the University of California, San Francisco (UCSF)

Posted by on March 20th, 2018

Two Postdoctoral positions are immediately available at the University of California, San Francisco (UCSF), in the laboratory of Sarah Knox. Position 1: The applicant will be part of an NIH-funded investigation into the development, regeneration and aging of exocrine organs including salivary glands, pancreas and ocular organs. The project specifically focuses on nerve-stem cell communication and[…]

Fully-funded International Ph.D. positions in Pancreas Biology

Posted by on March 20th, 2018

The Landsman Lab invites highly motivated students to join its effort to decipher the role of the microenvironment in beta-cell development and function. We combine transgenic mouse systems with physiological, morphometric and molecular tools to define cell-cell interactions within the pancreas, with the aim of facilitating cell replacement therapy for diabetes. The lab welcomes outstanding[…]

Abcam & the Node meeting reporter competition winner: Zubair Nizamudeen

Posted by on March 20th, 2018

Earlier in the year we and Abcam ran a competition to find a meeting reporter for the upcoming Abcam Adult Neurogenesis meeting to be held in Dresden in May. Today we are delighted to announce the winner: Zubair Nizamudeen, a PhD student in Virginie Sottile’s lab at the Wolfson STEM Centre, School of Medicine, University of Nottingham, UK. Zubair’s[…]

When the obvious fails, look at the unexpected: interneuron individual behavior affects the population migration.

Posted by on March 19th, 2018

The story behind our paper: Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. Carla G. Silva, Elise Peyre, Mohit H. Adhikari, Sylvia Tielens, Sebastian Tanco, Petra Van Damme, Lorenza Magno, Nathalie Krusy, Gulistan Agirman, Maria M. Magiera, Nicoletta Kessaris, Brigitte Malgrange, Annie Andrieux, Carsten Janke, Laurent Nguyen   The research behind this article is a[…]

In vivo profiling of chromatin accessibility with CATaDa

Posted by on March 13th, 2018

The following post is an introduction into the technnique described in our recent paper: Aughey, G.N., et al., CATaDa reveals global remodelling of chromatin accessibility during stem cell differentiation in vivo. Elife, 2018. 7.   Attempting to understand the biology of a complex organ, like the brain, comes with an array of technical challenges. Those[…]

Post-Doc Positions in Cell Biology/Neurosciences

Posted by on March 13th, 2018

  We are currently seeking applications from post-doctoral candidates (LabEx-funded positions). Project: Christophe Heinrich “Cellular Reprogramming and Brain Repair” was recently awarded a LabEx Attraction Package at SBRI. Our group focuses on direct lineage reprogramming of somatic cells into induced neurons as a novel cell-based therapy for brain repair. We previously showed that glial cells[…]

Manipulating the Mouse Embryo: Yesterday, today, and tomorrow… Symposium in honor of Professor Brigid Hogan

Posted by on March 13th, 2018

Last Friday March 9, a research symposium was held at Duke University in Durham, North Carolina to honor the career and retirement of Professor Brigid Hogan, Chair of the Department of Cell Biology (Hogan Lab Webpage: Current and former Hogan Lab members, colleagues, and friends came from across America, Japan, and the United Kingdom[…]