I am a Lecturer at the University of Manchester. My research is focused on understanding the biological mechanisms of genetic disease, with the goal of developing novel therapies. In particular, I use animal models to investigate rare and lower urinary tract disorders. My laboratory uses a battery of molecular, physiological and imaging techniques to elucidate the pathobiology underlying early onset bladder conditions. Furthermore, I have pioneered gene delivery to affected tissues in order to treat the condition in animal models with goal of bringing these therapies to the clinic. I am also interested more broadly in genetic diseases and closely collaborate with experts in Genomic Medicine to model a wide range of rare diseases.