the community site for and by developmental biologists

How do new cell types evolve? Sea urchins show the way….

Posted by on November 21st, 2019

We know surprisingly little about how evolution has created new cell types. One of the best examples of a recently evolved cell type comes from early sea urchin development. Most sea urchins produce a group of early embryonic cells known as micromeres- four small blastomeres that form by unequal cell division at the vegetal pole[…]

The Company of Biologists announces pilot transitional open access agreement with Jisc

Posted by on November 21st, 2019

The Company of Biologists, publisher of Development, is excited to announce a two-year pilot transitional open access (OA) agreement with Jisc from January 2020. The ‘Read and Publish’ deal will permit researchers at participating institutions unlimited access to all three subscription journals from The Company of Biologists, including the full archive dating back as far as 1853,[…]

A biology-modeling crosstalk to uncover feather pattern evolution

Posted by on November 20th, 2019

Richard Bailleul, Jonathan Touboul and Marie Manceau   Patterning in question: 60 years of mathematical and biological studies The coat of Vertebrates displays a stunning diversity of motifs created by the spatial arrangement of appendages and pigments across the skin surface. Strikingly, many have similar periodicity (i.e., number of repetitions within a period of space[…]

10 days to apply for a Travelling Fellowship from The Company of Biologists!

Posted by on November 19th, 2019

The Company of Biologists’ journals – Development, Journal of Cell Science, Journal of Experimental Biology and Disease Models & Mechanisms – offer Travelling Fellowships of up to £2,500 to graduate students and post-doctoral researchers wishing to make collaborative visits to other laboratories. These are designed to offset the cost of travel and other expenses. There is no restriction on nationality. They really[…]

The people behind the papers – George Britton and Aryeh Warmflash

Posted by on November 15th, 2019

This interview, the 71st in our series, was recently published in Development.  Our understanding of many fundamental aspects of early human development is still in its infancy, but a promising avenue for research uses advanced in vitro culturing techniques. For instance, confining human embryonic stem cells to micropatterned substrates and directing differentiation with signalling molecules has proved a powerful[…]

European Worm Meeting 12-15 July 2020 Marseille

Posted by on November 13th, 2019

We are pleased to announce that registration is open for the 2020 European C. elegans Meeting Invited speakers Meital Oren-Suissa, Ana Carvalho, Eric Miska, Nicolaus Rajewsky, Sophie Jarriault & Barbara Conradt; >45 talks to be select from abstracts. Bargain rates for early birds!   (No Ratings Yet) Loading…

How do cells know their future and forget their past

Posted by on November 7th, 2019

All cells in the body contain the same genetic material. The difference between cells therefore depends solely on which genes are expressed or ‘turned on’. Now, researchers from the University of Copenhagen have gained new insights into how genes are turned on and off and how the cells “forget their past” while developing into a[…]

The people behind the papers – Mingxi Deng and Yan Yan

Posted by on November 7th, 2019

This interview, the 70th in our series, was recently published in Development.  Drosophila wing discs are epithelial sac-like organs and a powerful model for investigating the link between proliferation and patterning. Of particular interest is the question of how single cells in the disc integrate information regarding position and growth control, as morphogens that pattern an axis can[…]

Genetics Unzipped – The future is now: Curing HIV, advancing CRISPR therapies, predatory phages for superbug infections

Posted by on November 7th, 2019

Exploring the latest advances in health technology such as CRISPR-based gene therapies, infection-fighting bacteriophage and a cure for HIV.