the community site for and by developmental biologists

A gnawing question: which cells are responsible for tooth renewal and regeneration?

Posted by on October 23rd, 2019

By Amnon Sharir (UCSF), Allon M Klein (HMS), Ophir D Klein (UCSF) As most mouse geneticists know, treating a rodent with malocclusion of its front teeth can be a Sisyphean task: as much as one trims the tooth, it grows right back within a few days (Figure 1). The basis of this often-frustrating situation is that[…]

Mammalian Genetics & Development Workshop – 30th anniversary!

Posted by on October 21st, 2019

A meeting of the Genetics Society  3rd December 2019 Venue: UCL Institute of Child Health, Guilford Street, London, WC1N 1EH Organisers: Nick Greene (UCL), Cynthia Andoniadou (KCL), Andy Copp (UCL) The Mammalian Genetics and Development Workshop is an annual meeting focusing on the development and genetics of mammals.  The Meeting is based on the submitted abstracts,[…]

Chromatin and epigenetics in development: a Special Issue

Posted by on October 15th, 2019

This editorial was recently published in Development and written by our editors Benoit Bruneau, Haruhiko Koseki, Susan Strome, Maria-Elena Torres-Padilla. Check out the Special Issue’s full table of contents here. The development of an organism is regulated by tightly coordinated changes in gene expression. From zygotic gene activation, through to lineage specification and organogenesis, and into[…]

Cancer Research UK’s Children and Young People’s Innovation Awards

Posted by on October 11th, 2019

Cancer Research UK have launched two funding calls to drive progress in our understanding of paediatric cancers. We would like to encourage proposals to investigate one or more of the following concepts- The basis of tumour initiation and progression Novel therapeutic approaches Development of novel biomarkers or methodologies to predict disease progression, to enhance efforts[…]

The people behind the papers – Qiang Zhu, Marçal Gallemí and Eva Benková

Posted by on October 10th, 2019

This interview, the 69th in our series, was recently published in Development.  The apical hook is a transient structure that functions to protect the vulnerable apical meristem from damage when the seedling penetrates the soil. Although some of the molecular players regulating its development have been identified, many aspects have remained opaque, including how an early auxin[…]

Genetics Unzipped – Exploring the poop-ome, from microbiomes to metagenomics

Posted by on October 10th, 2019

We’re getting our hands dirty by delving into the poop-ome – the trillions of bacteria that live inside our guts and make up what’s known as the microbiome.

Features & Reviews Editor on Journal of Cell Science

Posted by on October 9th, 2019

Journal of Cell Science, published by The Company of Biologists, is seeking enthusiastic and motivated applicants for the role of Features & Reviews Editor. Joining an experienced and successful team, including Editor-in-Chief Michael Way, this is an exciting opportunity for a talented scientific editor to make a significant contribution to an important journal in the[…]

The story behind the cover: Annabel Ebbing’s worm art

Posted by on October 9th, 2019

Development covers showcase the beauty of developmental biology. Embryos, tissues and cells are rendered in striking colour palettes and artistic arrangements. We mainly receive confocal image submissions but sometimes also EM and standard light microscopy. And sometimes, art – like our most recent cover, a schematic overview of C. elegans created by Annabel Ebbing, PhD student in Hendrik Korswagen’s lab at the[…]

Development Special Issue: The Origins and Mechanisms of Developmental Disorders

Posted by on October 3rd, 2019

Development invites you to submit your latest research for our upcoming special issue: The Origins and Mechanisms of Developmental Disorders. This issue will be coordinated by two guest editors: Sally Dunwoodie and John Wallingford. Developmental disorders are among the most lethal diseases of childhood, and this recent decade has witnessed significant advances in our understanding of their genetic and environmental[…]