the community site for and by developmental biologists

The people behind the papers – Charles Sheehan, John McMahon and Debby Silver

Posted by on May 27th, 2020

This interview, the 76th in our series, was published in Development earlier this year.  Interneurons are crucial to cortical function and their dysregulation has been implicated in various neurological pathologies, yet how they are generated during development is still poorly understood. A new paper in Development investigates interneuron neurogenesis in the mouse embryo and its[…]

Research Highlight #3: IL-1 regulates haematopoietic stem cell pool size via PU.1

Posted by on May 25th, 2020

Today, we move to mouse adult haematopoiesis, with an elegant work on inflammation and stem cell biology. As always, feedback is more than welcome! Chronic inflammation is one of the classic events underlying aging and infection response. When associated with loss of quiescence in haematopoietic stem cells (HSCs), it is commonly the initiating event in[…]

Staying connected during the COVID19 pandemic

Posted by on May 21st, 2020

Among many other (many more important) things, pandemic times have meant an end to travel, which for the Development team means no conferences and no lab visits. For me personally, it’s meant cancelled trips to Shanghai, Kyoto, Washington and Chicago, and while I’m delighted to be keeping my carbon footprint down, I’m definitely missing the[…]

List of virtual talks, seminars, forums

Posted by on May 21st, 2020

Updated 28 May. Let us know if we missed anything Please take Development’s survey about a potential series of developmental biology webinars: https://www.surveymonkey.co.uk/r/developmentwebinars   Various organisations and looser assemblies of locked down researchers have begun to put together online seminar and talk series, many of which are open to anyone (usually with registration), and many[…]

Genetics Unzipped podcast: From one generation to the next – the life and work of Dame Anne McLaren

Posted by on May 21st, 2020

Kat Arney reflects on the life and work of Dame Anne McLaren, one of the leading embryologists of the 20th century.

Getting involved in peer review

Posted by on May 19th, 2020

In pre-COVID19 times, back when conferences happened largely in person, early career researchers (ECRs) often asked me how they could get more direct invitations to be a reviewer. Peer review is a crucial part of the publishing ecosystem and therefore it’s not uncommon for group leaders to invite members of their lab to review articles[…]

Last chance to take our user survey

Posted by on May 19th, 2020

We’ve had a great response so far to our tenth birthday user survey, which we hope will guide us going forwards and give us ideas for how we can better serve the developmental biology and stem cell community. If you haven’t taken it yet, it closes Thursday midday BST. Even if you’re a less-than-occasional reader,[…]

Research Highlight #2: Blood stem cells heterogeneity arises from accessible chromatin

Posted by on May 18th, 2020

Hi there! Today’s highlight is focusing on a major question for the haematology community: what is causing blood stem cell heterogeneity? Please do not hesitate to let me know your thoughts in the comments here or on Twitter (@BioRugby)!   Highlight #2: Chromatin accessibility is the main source of heterogeneity in foetal haematopoiesis We have[…]

Cilia, Reissner Fiber and Crooked Spines

Posted by on May 18th, 2020

Perhaps the most exciting aspect of attending any scientific meeting is the privilege of becoming aware of novel research findings in our fields of interest, prior to their appearance in published literature – and this begins as soon as we have the abstract book in hand! Sitting in my hotel room in Suzhou, and browsing[…]