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“My balance comes from instability” thought Herzog (Saul Bellow, Herzog)

Posted by on October 28th, 2019

A bit of background The dependence of a protein’s function on its structure is a well-known phenomenon. Back in 1970’s, it was suggested that most proteins would fold into one energetically stable or favorable conformational state in the cell determined by their primary amino acid sequence. This led to the notion of “one sequence to[…]

CRISPR-Cas9 – what’s left to know?

Posted by on August 8th, 2019

This post was originally posted on the MRC Weatherall Institute of Molecular Medicine’s blog Dominic Owens, PhD student in the De Bruijn group at MRC MHU, recounts how puzzling results and a fortuitous lab meeting uncovered unexpected outcomes of CRISPR editing and changed the direction of his research.   It’s May 2018 and I’m feeling nervous. I was[…]

A day in the life of an onychophoran lab

Posted by on August 7th, 2019

What are onychophorans and why do we study them? My name is Sandra Treffkorn, and I recently finished my PhD in the department of zoology lead by Georg Mayer at the University of Kassel, Germany. In our research group, we focus on studying the evolution of animal diversity by investigating two very interesting but largely[…]

Ph.D. and Post Doc positions in plant development, morphogenesis and evolution

Posted by on July 24th, 2019

The Department of the Director Prof Miltos Tsiantis is looking for early stage researchers to employ at the Ph.D. and Post Doc level in the areas of plant development, morphogenesis and evolution ( Ph. D. candidates should have an M. Sc in appropriate discipline (Plant biology, Developmental biology, Computer Science, Genetics, Biochemistry, Statistical, Evolutionary or[…]

Post-doctoral position in the Tsiantis lab, MPIPZ, at the interphase of development and metabolic physiology

Posted by on June 28th, 2019

We have previously characterized processes underlying diversity in leaf form between and within species and have identified genetic pathways influencing this trait. Here, we propose to investigate the possible physiological and metabolic significance of this variation, as well as possible feedbacks between metabolism and leaf form. The project will involve comparative studies of Cardamine hirsuta[…]

The Pros and Cons of having an ELN: What I’ve learned from my time in a wet lab

Posted by on June 24th, 2019

With its growing adoption in the laboratory, an electronic lab notebook, or ELN, can be a useful tool to aid research, whether in academia or industry. But I found there is limited information on the practicalities of an ELN in a wet lab. Wet labs are a messy business, so strict guidelines are put in[…]

Decoding light for developmental timing

Posted by on June 13th, 2019

Shruti Vemaraju¹ and Richard A. Lang¹-²  ¹Center for Chronobiology,¹The Visual Systems Group, Abrahamson Pediatric Eye Institute, Division of Pediatric Ophthalmology, ²Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA. ²Department of Ophthalmology, University of Cincinnati, College of Medicine, Cincinnati, OH 45229, USA   We live on a planet that is close to[…]

Collaboration: All the things we cannot see (alone).

Posted by on June 3rd, 2019

By Miriam Rosenberg and Suparna Ray Most of what we know about axial patterning in insects comes from decades of careful, beautiful work done in flies. Thanks to the genetic screens of Christiane Nüsslein-Volhard and Eric Wieschaus in the late 1970’s, we learned that distinct classes of genes, many of them transcription factors, act in[…]

A day in the life of a Termite lab

Posted by on May 31st, 2019

How do genes and their environment interact during development and evolution to generate phenotypic diversity? To answer these questions in the Miura lab, by focusing on diverse animal taxa, we are studying physiological and developmental mechanisms of phenotypic changes in animal life cycles in response to environmental shifts. By the way, I’m Kohei Oguchi, a[…]

PhD position: Evolutionary origin of synaptic proteins at the Sars Centre in Bergen, Norway

Posted by on April 30th, 2019

PhD position There is a vacancy for a 4-year PhD student position at the Sars International Centre for Marine Molecular Biology in the research group of Dr. Pawel Burkhardt ( The position is funded by Sars Centre core funding. The Sars Centre belongs to the University of Bergen and is partner of the European Molecular[…]