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Discovering the Genetic Basis of Mimetic Color Diversity in Bumble Bees

Posted by on August 20th, 2019

As a first-year graduate student, I had the good fortune of accompanying Dr. Pierre Rasmont (U. Mons, Belgium) and his lab group on an expedition to collect bumble bees in Turkey. At our first stop onto the dry but flower-rich volcanic lands, we each dispersed to collect bees. At the time I was working to[…]

Turning back the clock of neural progenitor cells: a simple recipe to generate de novo retinal ganglion cells

Posted by on August 12th, 2019

Press release for a new Development paper on reprogramming in the retina. Scientists at the Federal University of Rio de Janeiro, Brazil, in collaboration with the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, discovered that a single transcription factor drives retinal progenitor cells to reacquire the potency to generate Retinal ganglion cells. The[…]

CRISPR-Cas9 – what’s left to know?

Posted by on August 8th, 2019

This post was originally posted on the MRC Weatherall Institute of Molecular Medicine’s blog Dominic Owens, PhD student in the De Bruijn group at MRC MHU, recounts how puzzling results and a fortuitous lab meeting uncovered unexpected outcomes of CRISPR editing and changed the direction of his research.   It’s May 2018 and I’m feeling nervous. I was[…]

How to “Run” embryonic development

Posted by on July 24th, 2019

The term “embryonic development” was originally proposed some 2,400 years ago by Aristotle, however, many aspects of how the genome regulates development remain unclear. One major challenge of the modern Genomics Era is to better understand how transcriptional factors, transcriptional activators and repressors, regulate gene expression in order to support spatiotemporal outputs that change over[…]

Ph.D. and Post Doc positions in plant development, morphogenesis and evolution

Posted by on July 24th, 2019

The Department of the Director Prof Miltos Tsiantis is looking for early stage researchers to employ at the Ph.D. and Post Doc level in the areas of plant development, morphogenesis and evolution (http://www.mpipz.mpg.de/226344/tsiantis-dpt). Ph. D. candidates should have an M. Sc in appropriate discipline (Plant biology, Developmental biology, Computer Science, Genetics, Biochemistry, Statistical, Evolutionary or[…]

Development at the single cell level

Posted by on July 17th, 2019

Development recently published a bumper Special Issue devoted to single cell approaches to developmental biology. A multitude of model systems featured – from Dicty to Drosophila to mouse to zebrafish – and the issue’s Reviews, Spotlight and Hypothesis gave an overview of the field’s current challenges and opportunities.     The cover was chosen by[…]

POSTDOC IN NEURODEVELOPMENT

Posted by on July 5th, 2019

Location: Applications are invited from highly motivated individuals interested in fundamental mechanisms of neurodevelopment and disease.The focus of the project is to understand neural developmental and behavioural phenotypes in mouse models of Tuberous Sclerosis Complex (TSC1 conditional mouse mutant). The fellowship is in the laboratories of Sara Wilson at the Department of Integrative Medical Biology (IMB), and Leif Carlsson[…]

The 2019 North of England Cell Biology Forum

Posted by on July 2nd, 2019

This annual 1-day symposium brings together cell biologists from the North of England. There is a full day of talks and a poster session where junior scientists are encouraged to present their work. PhD students and post-docs are invited to apply for oral and/or poster presentations; prizes will be awarded on the day. Date: Thursday,[…]

Post-doctoral position in the Tsiantis lab, MPIPZ, at the interphase of development and metabolic physiology

Posted by on June 28th, 2019

We have previously characterized processes underlying diversity in leaf form between and within species and have identified genetic pathways influencing this trait. Here, we propose to investigate the possible physiological and metabolic significance of this variation, as well as possible feedbacks between metabolism and leaf form. The project will involve comparative studies of Cardamine hirsuta[…]

Research Scientist Position on Diabetes and Stem Cell Research in Dresden

Posted by on June 26th, 2019

Research Scientist Position German Centre for Diabetes Research Dresden A research scientist position is available in the research group of Dr Anthony Gavalas. The group investigates the role of signaling pathways and metabolism in the late stages of endocrine pancreas development, the application of novel signals for the conversion of human pluripotent stem cells into[…]