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Development Special Issue: The Origins and Mechanisms of Developmental Disorders

Posted by on October 3rd, 2019

Development invites you to submit your latest research for our upcoming special issue: The Origins and Mechanisms of Developmental Disorders. This issue will be coordinated by two guest editors: Sally Dunwoodie and John Wallingford. Developmental disorders are among the most lethal diseases of childhood, and this recent decade has witnessed significant advances in our understanding of their genetic and environmental[…]

Down from the crest to clear the dead

Posted by on September 30th, 2019

Yunlu Zhu & Sarah Kucenas   Introduction Cells are the building blocks of life. However, in multi-cellular organisms, millions of cells are subject to death due to injury, infection and ordinary cell turnover (Galluzzi et al., 2018). For example, epithelial cells in the small intestine rapidly renew every 2 to 6 days in most mammals,[…]

The serpent’s maw: mouth function and the dynamics of Hydra regeneration

Posted by on September 30th, 2019

One of the biggest open questions in biology is how organisms can form complex patterns (limbs, organs, entire body plans) from initially disordered or very simple states. Every animal does this at the beginning of its life, forming its full complexity from a single cell. Some are capable of similar feats even after their bodies[…]

Using hemimetabolous insects to investigate the origin of the tra-dsx axis

Posted by on September 24th, 2019

The story behind our recent paper in eLife.   Rapid turn over of sex determination mechanisms provides biologists with an elegant study system connecting sexual selection to molecular evolution. Striking examples of this turnover are found in African cichlids, where multiple sex determination signals exist not only within the same genera, but sometimes within the[…]

Moving in concert: How lateral line primordium cells coordinate to migrate

Posted by on September 21st, 2019

Written by Tugba Colak-Champollion Story behind our recent paper in Current Biology “Cadherin-Mediated Cell Coupling Coordinates Chemokine Sensing across Collectively Migrating Cells” (Tugba Colak-Champollion, Ling Lan, Alisha R. Jadhav, Naoya Yamaguchi, Gayatri Venkiteswaran, Heta Patel, Michael Cammer, Martin Meier-Schellersheim, Holger Knaut)   Guided cell migration is a crucial event in many biological and mechanical processes.[…]

Inflate your embryo

Posted by on September 17th, 2019

How would you create a hole between two sticky surfaces? Simply crack it! At a first glance, trying to pull apart the two surfaces seems to be a good idea, but in practice, you might need a lot of energy. However, it seems that the mouse embryo has found a smart and efficient way to do[…]

Stowers Research Conferences: Developmental Cell Biology

Posted by on September 12th, 2019

Stowers Research Conferences are biennial meetings that bring together researchers, faculty, and graduate students to inspire creative thought and collaboration in the basic sciences. The Developmental Cell Biology meeting will include 11 speakers with 13 talks chosen from abstracts, 2 poster sessions and a conference party to close the meeting. April 22-24, 2020 Abstract Deadline: January[…]

Genetics Unzipped podcast: Big Questions about the Big C

Posted by on September 12th, 2019

We’re digging into some of the mysteries around what’s often seen as the ultimate genetic disease: cancer.

Data Visualization with Flying Colors

Posted by on August 29th, 2019

The importance of barrier-free use of colors in images and graphs has been highlighted in letters to editors (Miall, 2007), papers (Geissbuehler and Lasser, 2013, Levine, 2009), editorials (anonymous, 2007), columns (Wong, 2011) and on numerous web pages. One of the recommendations is to use a color blindness simulator. Having a color vision deficiency myself,[…]

Postdoctoral Positions – Adipocyte Development and Obesity

Posted by on August 27th, 2019

Postdoctoral Felow positions are open in the Division of Endocrinology and the Division of Developmental Biology of Cincinnati Children’s Hospital Medical Center in the laboratory of Dr. Sanchez-Gurmaches. The goal of Dr. Sanchez-Gurmaches lab is to understand the mechanisms that drive the normal and pathological formation and function of distinct types of adipocytes with the long-term goal[…]