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developmental and stem cell biologists
Posted by DMDD, on 15 June 2018
Following our latest data release, the DMDD website (dmdd.org.uk) now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb ...Posted by DMDD, on 8 August 2017
Deciphering the Mechanisms of Developmental Disorders (DMDD) is a large-scale imaging and phenotyping programme for genetically modified mouse embryos. For embryos at E14.5, the key imaging technique is High Resolution ...Posted by DMDD, on 20 July 2017
A new set of DMDD embryo and placenta data has been released, taking our total dataset to 9.5 million images of around 1300 embryos. DMDD is a primary screen of ...Posted by DMDD, on 11 April 2017
A large-scale study of DMDD data has shown that inactivating the same gene in mouse embryos that are virtually genetically identical can result in a wide range and severity ...Posted by DMDD, on 21 February 2017
A new paper published in Journal of Anatomy shows that measuring the amount of inter-digital webbing in mouse embryos between 14 and 15 days gestation is the best way to find ...Posted by DMDD, on 7 February 2017
New DMDD data released on Expression Atlas reveals the effect of single gene knockouts on the expression of all other genes in the mouse genome. The gene expression profiles of ...Posted by DMDD, on 1 December 2016
This post originally appeared on Annotations, the DMDD blog. New image and phenotype data for embryos and placentas from embryonic lethal knockout mouse lines has been made ...Posted by DMDD, on 4 October 2016
This post first appeared on Annotations, the DMDD blog (blog.dmdd.org.uk). Around a third of targeted gene knockouts in mice are embryonic-lethal. But not all deaths occur during gestation – a ...