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Displaying posts with the tag: mouse-blastocyst [Clear Filter]

Embryonic hydraulics triumphs

Posted by on June 26th, 2019

In this article I share with you a more personal, chronological account of how our story unfolds (recently published in Nature), and highlight some key events and insights that help guide the direction of the study, which are not described in the publication. Readers are welcome to refer to the publication for more technical details.[…]

GATA6 and the power of single cells

Posted by on May 29th, 2014

Any mammal who celebrated Mother’s Day earlier this month realizes how important mothers are for us and the tight bond between them and their children. Forget clean shirts and packed lunch every day; for us developmental biologists, there is no better reflection of this bond than the extraembryonic membranes that support the growth of the[…]

An Interview with Janet Rossant

Posted by on September 13th, 2011

I arranged to talk to Professor Janet Rossant after her talk at The EMBO Meeting here in Vienna. Janet is Chief of Research at The Hospital for Sick Children in Toronto, besides being a University Professor at the University of Toronto. Throughout her career she has been and still is making major contributions to the[…]

In Development this week (Vol 137, Issue 20)

Posted by on September 28th, 2010

A fateful look at early mouse lineage specification The first cell lineages specified in the mouse embryo are the trophectoderm (TE), which generates the embryonic portion of the placenta, and the inner cell mass (ICM). The ICM subsequently forms the pluripotent epiblast (EPI, which produces the embryo) and the primitive endoderm (PrE, which generates other[…]