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CRISPR-Cas9 – what’s left to know?

Posted by on August 8th, 2019

This post was originally posted on the MRC Weatherall Institute of Molecular Medicine’s blog Dominic Owens, PhD student in the De Bruijn group at MRC MHU, recounts how puzzling results and a fortuitous lab meeting uncovered unexpected outcomes of CRISPR editing and changed the direction of his research.   It’s May 2018 and I’m feeling nervous. I was[…]

Specifying stem cells, specifically

Posted by on February 5th, 2015

Bone marrow transplants save lives. It’s as simple as that. The reason bone marrow transplants are so effective is because this squishy tissue is home to haematopoietic stem cells (HSCs), which spend their lives happily producing every single blood cell that will ever circulate around your body. As a result, if anything goes wrong with[…]