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1DegreeBio: antibody resource with stem cell portal

Posted by on August 13th, 2012

I just came across a press release that looked like it might be interesting to some of you: 1DegreeBio has launched a Stem Cell Portal on its site, that allows you to easily find user reviews and protocols for antibodies used in stem cell research.

1DegreeBio is a relatively new company and the database of reviews is still incomplete, but they do have long lists of antibodies for various targets, and an easy interface for search queries. For example, of the more than two hundred listed antibodies against POU5F1, only two have currently been reviewed by users, and another three were linked to relevant publications.


The search screen

The resource is free to use, though, and if you submit your own reviews of the antibodies you use, you can earn points that you can then spend in their shop, on Amazon gift cards or geeky toys, or donate to charity.

As the number of reviews on the site grow, you’ll be able to make more accurate assessments on the functionality of various antibodies. It seems especially useful for antibodies from certain companies that don’t do any quality testing themselves, but that are sometimes unavoidable when no other supplier sells the antibody you need. I do wonder how 1DegreeBio will be able to ensure that all reviews are done by actual independent researchers, and not left by employees of the companies selling the products, but that is something that might also be less of an issue as the number of reviews grows.

If any of you are using the 1DegreeBio site and their stem cell portal, feel free to leave a comment about your experience. I didn’t sign up myself, because I’m no longer using antibodies, but I’ve gone through many, many vials during my PhD, and have emailed several companies to check species specificity (“Does your human antibody also work with mice?”). If this kind of “Yelp for antibodies” had existed back then I’m sure I would have left many reviews about extreme variation in batch strength, unidentified cross-reactivity, and the few unexpectedly perfect antibodies that saved my thesis.
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  1. Alex Hodgson says:
    Thanks for profiling our newly released portal!

    We’re building our arsenal of reviews, but as you pointed out, there are a large number of suppliers offering an even larger number of research grade antibodies. We are a community focused site, so if you have used an antibody or kit lately, please share your experience - not only can it help a a colleague avoid a great deal of frustration, but we also offer $5 per review you submit with an image.

    Not using antibodies anymore? Well, we also take reviews on service providers which range from custom antibody services to DNA and peptide synthesis.

    To answer your question, each user who contributes is actually manually verified to ensure that the contributor is an active lab member at a recognized institution. Reviews also are subject to an approval process to ensure that no one is just taking them from other site, re-using images etc.

    If you have any other questions, or have some feedback for us, please don’t hesitate in letting us know - it’s the only way we can make the tool better!

    Thanks again for the shout-out!

    Alex and the 1DegreeBio Team.


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  2. Kris says:
    I hadn’t heard of it before but this looks worth taking a peak at! If I use one more antibody from S*#&$ C&$^ that doesn’t work I may lose my last shred of sanity


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  3. Smitha787 says:
    Very nice! ecdfekdfbd


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