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An interview with Jenny Nichols

Posted by on August 17th, 2017

This interview by Aidan Maartens originally appeared in Development, Volume 143, Issue 16. Jennifer Nichols is a Principal Investigator at the Cambridge Stem Cell Institute and Department of Physiology, Development and Neuroscience at the University of Cambridge, UK. Her lab works on lineage segregation and the establishment of pluripotency in the mammalian embryo. In 2017 she was[…]

In Development this Week (Vol. 144, Issue 15)

Posted by on August 15th, 2017

Here are the highlights from the current issue of Development:   PLCζ ‘waves in’ mammalian oocyte activation At fertilisation, fusion of the sperm with the oocyte activates a slew of downstream processes to kick-start embryogenesis. This ‘oocyte activation’ event induces the cortical reaction to prevent polyspermy, triggers oocyte metabolic and DNA synthesis pathways, and reactivates meiosis. In[…]

An interview with Jim Smith

Posted by on August 3rd, 2017

To interview Jim Smith I took a train to London and visited the Francis Crick Institute for the first time. The building had opened in 2016 and, by the time I visited, most if not all of the labs had settled in. Architecturally it was quite stunning, especially looking down from one of the higher[…]

Reactions to the CRISPR human embryo paper

Posted by on August 3rd, 2017

A paper published online yesterday in Nature (and ‘leaked’ a week ago by the MIT Technology Review) describes the use of CRISPR in human embryos to correct a mutation that causes hypertrophic cardiomyopathy. The work has hit the headlines and sparked debate about its utility and implications. Collated below are responses from the field (or[…]

July in preprints

Posted by on August 1st, 2017

Our latest monthly trawl for developmental biology (and other cool) preprints. See last year’s introductory post for background, and let us know if we missed anything This month we found lots of plant preprints and plenty of evo-devo work, as well as a series of preprints characterising features of the genome at distinct stages or places during development. The[…]

In Development this Week (Vol. 144, Issue 15)

Posted by on August 1st, 2017

Here are the highlights from the current issue of Development:   X-citing insights into dosage compensation The non-coding RNA Xist plays a key role in the process of X chromosome inactivation (XCI) and is thus essential for dosage compensation of X-linked genes in females. The 5′ region of Xist RNA contains a conserved element termed the A-repeat that is required for[…]

Editorial changes

Posted by on July 24th, 2017

This Development Editorial appeared as an advanced online article on 21 July. Olivier Pourquié, Katherine Brown   Here at Development we are very sad to be saying goodbye to two of our editors: Ottoline Leyser and Geraldine Seydoux. Both Ottoline and Geraldine have been valued members of the editorial team since 2011, and we are[…]

Unfolding collaboration

Posted by on July 18th, 2017

We came across this video from EuroStemCell describing a project that aimed to increase public awareness of stem cell biology, as well as encourage scientists to get involved in public engagement and interact with other professionals along the way. In their introduction to the video, EuroStemCell give us the background:   “Creative public engagement initiatives are[…]

Four recent science art & photography announcements

Posted by on July 13th, 2017

Worm art at #Worm17 Each year at the International C. elegans Conference Ahna Skop organises a Worm Art Show with winners selected by the meeting participants (find out more about the history of the show here).  2017’s winners have just been announced – read about them over at the GSA’s Genes to Genomes blog (a great site for your bookmarks[…]

From our sister journals

Posted by on July 10th, 2017

Here we highlight some developmental biology related content from other journals published by The Company of Biologists.         Jacky Goetz, who works on intravital imaging methods and biomechanical forces during tumour development, was featured as a Cell Scientist to Watch   David Bryant and Aaron Johnson reported from The Company of Biologists’ workshop ‘Intercellular interactions in[…]