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Young Group Leader Positions in Stem Cell Biology – Institut Pasteur, Paris, France

Posted by on May 21st, 2013

The Institut Pasteur announces an international call for candidates wishing to establish independent research groups on its Paris, France campus. The recruitments are part of the Revive Laboratory of Excellence (LabEx) programme, recently awarded to the Institut Pasteur on “Stem Cells and Regenerative Biology and Medicine”. Candidates will be integrated into the cutting edge interdisciplinary environment provided by the Department of Developmental & Stem Cell Biology. Candidates specializing in the field of stem cells in the context of developmental and cell biology, genetics, epigenetics, regeneration, translational research and ageing are encouraged to apply.

 

To be eligible, candidates must have defended their PhD on or after June 20, 2005 (women with children are eligible up to 10 yrs after their Ph.D). Successful candidates will be appointed as head of a group of up to 6 people for a period of 5 years. The budget (up to 1,500,000€ over 5 years) includes the salary for the group leader, a three-year postdoctoral position, a technician’s position, part-time secretarial assistance, a substantial contribution to running costs and equipment, and access to on-campus facilities including state-of-the-art technology core facilities.

 

Candidates should send their formal applications by E-mail to the Director of Scientific Evaluation, Prof. Alain Israël, at the Institut Pasteur (g5revive@pasteur.fr). The deadline for applications is June 20, 2013. Short-listed candidates will be contacted for interview to be scheduled for beginning of September 2013 and recruitment decisions announced by October 2013. Further information on the Revive program can be found at http:// www.pasteur.fr/revive

 

Applicants should provide the following (in order) in a single pdf file:

1. A brief introductory letter of motivation, including the name of the proposed group. Candidates are encouraged to contact the coordinator of the Revive programme Shahragim Tajbakhsh (shaht@pasteur.fr).
2. A Curriculum Vitae and a full publication list.
3. A description of past and present research activities (up to 5 pages with 1.5 spacing; Times 11 or Arial 10 font size).
4. The proposed research project (up 10 pages with 1.5 spacing; ; Times 11 or Arial 10 font size).
5. The names of 3 scientists from whom letters of recommendation can be sought, together with the names of scientists with a potential conflict of interest from whom evaluations should not be requested.
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Bullying in the lab

Posted by on May 14th, 2013

The lab can be one of the greatest places in the world to make live long friends. Spending countless hours in a tissue culture room late into the middle of the night, sharing similar frustrations when experiments don’t work or talking about how your PI does not have a clue what they are talking about can really bring people together. This is also compounded by the fact that you will spend some of the most formative years of your life with these people. They’ll be the first people you see in the morning, the last people you see at night, and the people that you will spend most of your time socialising outside of the lab with.

However, pressure in every profession can push people to the edge and increase tensions between lab members and in some cases result in bullying. Unfortunately, education does not prevent bullying from occurring in academia and is sadly somewhat a regular occurrence within labs and surprisingly is still found to occur at the higher levels among faculty members.

For PhDs and Post-Docs the constant pressure to perform both technically and mentally can be a lot to handle. In some cases this can get the best of people, with envy being a consuming emotion that results in tension between lab members. Resenting other people in the lab due to their success no matter how big or small can result in the abuse or coercion of others and in some extreme cases result in bully’s tampering with their victims work and stealing their supplies.

Intimidation from other lab members is not the only place where this mental torture comes from, with many PI’s being some of the biggest bully’s within academia. On many occasions I have watched group leaders shout openly at their students, berate their work and on more than one occasion throw their lab book out the window.

One post-doc that I use to work with would go MIA for a few days after meeting with the PI, just to relieve the tension within the lab.  Another lab beside me would orientate a magnet on their freezer in a certain way to represent whether the PI was in or not, so much was the fear of dealing with her. On another occasion a PhD student friend of mine suffered intimidation for months from her PI and eventually was fired without cause. When they approached the HR department within the college they were told that the Professor was ‘too powerful’ and the college could do nothing to resolve their cause, leaving them with no choice but to leave quietly.

If you are suffering from bullying within the lab or know someone who is, directing them towards your university counselling service can always help. If not, lending a helpful ear or discussing your problems with a member outside of the lab might help them/you see the bigger picture and allow you get confront the problem.

www.postpostdoc.com
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myIDP (Individual Development Plan) by Science Careers

Posted by on February 21st, 2013

The myIDP (Individual Development Plan)  is career aptitude test and career planning site for scientists developed by Science Careers. I recently changed careers, starting my own scientific writing company after a postdoc in developmental biology, so I was interested to see how the software worked.

The first thing you do is go through a few stages of self-assessment. First, you judge your skills in different aspects of science (ex. writing for other scientists, establishing collaborations, mentoring others). The site gives you a list of skills and abilities, and you have to enter where you are on a 1-5 scale from “highly proficient” to “highly deficient”. The software reminds you often that you’re supposed to use the full range of scores, so you have to put aside your ego and rate yourself as “highly deficient” for at least a few key skills!

Second, you rate how often you would like to do certain tasks in your future career (ex. developing and optimizing techniques, negotiating with others, working on committees).

Last, you assess your values as they relate to your career (ex. is it important to you to help advance society, use your strengths frequently in your work, have a good work/life balance). These ratings aren’t used in the career match calculation, but it’s a useful list for self-reflection just the same.

At the end of the assessment, the software tells you the percentage match between your skills and interests and different categories of scientific careers. For me, I was happy to see Science Writing come in at number two, but I was bit surprised to see Sales and Marketing at number four (a field in which I have little interest− or skills for that matter!). Having just started my own business, I was a bit dismayed to see Entrepreneurship was near the bottom!

The output of the career matching function:



The site also includes some journaling-type functions. There are places to add notes about career contacts you’ve met, list your personal career goals and map out how you plan to get there. You can set all kinds of different goals and track your progress, such as for improving some of the skills from their checklist, setting milestones to advance your career, or establishing other career-related project goals, like teaching a class or writing a paper.

At the end you can print out everything you’ve entered, all the self-assessment and goals, as a “personal development plan”.

What I found more useful than the goal-setting and career-matching functions was simply the list of diverse scientific careers, many of which I’d never thought about before. The site has a resources section for each career category that gives links to further reading. For science writing and editing, this collection of links and articles hidden on the Science Careers website was really useful.
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Would you like to work for the Node?

Posted by on December 13th, 2012

As you may have spotted, we’ve just posted a job ad for community manager for the Node. That is currently my job, but I will be leaving at the end of February, so there will be a vacancy.

I’ve had this job since the Node launched, and even before then! I’ve had a great time setting up the site, meeting so many scientists around the world, and seeing the Node grow from nothing to a well-visited resource for the developmental biology community. You’ve all been great to work with, but now it’s time for me to move on, and for someone else to take over. Have a look at the job ad and apply if you’re interested. The office is based in Cambridge, UK. We… erm, I mean THEY are actually moving to a nice new office in a few months, too. The company publishes five journals, so you’ll learn a lot about publishing while you’re here as well.

For everyone else, to make it easier on the next community manager and in the transition phase, please remember that you do not need to ask for permission to post on the Node. If your account is approved, you can post. I’ve personally been okay with reading over some posts for grammar and spelling if you’ve asked me to, but this is really not necessary. The concept of the Node is such that you can share news without editorial input. Take advantage of your freedom to post!

My new job will be in London, and still in the scientific publishing-adjacent field, so I’m not going far, but I won’t be involved with the Node anymore. If you’d like to stay in touch with me, and find out what I’m doing next, your best bet is to find me on Twitter as @easternblot.


(Image: Wordle cloud created from the archive of monthly highlight posts)
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Editorial opportunities at the Company of Biologists

Posted by on November 6th, 2012

Here at Development, and at our sister journal Disease Models and Mechanisms, we are currently advertising two editorial positions.

Within the Development team, we are seeking to recruit a new Associate Reviews Editor with special responsibility for the stem cell field - reflecting the journal’s increasing visibility in that area. Further details on this exciting opportunity are available on the jobs page.

DMM also have a position for a Scientific Editor, and you can find more information on this opening here. Applicants with previous editorial experience are particularly encouraged.

Both jobs will be based at the Company of Biologists’ office in Cambridge, UK, and both provide a fantastic opportunity to work with a small not-for-profit publisher at the heart of the scientific community.
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Research Technician – Cell and Developmental Biology – MRC-NIMR

Posted by on September 12th, 2012

Applications are invited for a Research Technician position in the research group of James Briscoe at the MRC National Institute for Medical Research, London. The lab studies the embryonic development of the vertebrate central nervous system. We combine cutting edge transgenic and genomic approaches with the latest imaging and cell biology techniques to investigate how morphogens and transcriptional networks generate spatial pattern.

http://www.nimr.mrc.ac.uk/research/james-briscoe/

Experience in molecular biology is required and experience of cell culture, mouse genetics and embryological techniques desirable. Enthusiasm, reliability and organisational skills are essential. The successful applicant will be expected to support and become engaged in specific projects aimed at elucidating the mechanisms of neural patterning. The group, which will move to the Francis Crick Institute, London, in 2015, currently comprises 11 scientists and is well supported by both MRC and external funds. The Institute provides excellent training for researchers in a multi-disciplinary environment and is equipped with state of the art facilities. Specialist training to support the development of skills will be given where necessary.

The applicant is expected to have a Degree or equivalent in a relevant subject.

This position is for 5 years in the first instance. Salary range is from £21,565 per annum inclusive of location allowance. MRC final salary pension scheme is also available.

Situated in Mill Hill, North West London, the MRC National Institute for Medical Research is the largest MRC institute, supporting 70 research groups and 500 bench scientists. Facilities include genetic modification of mice, imaging, histology, FACS and high throughput sequencing.

Applications are handled by the RCUK Shared Services Centre; to apply please visit our job board at https://ext.ssc.rcuk.ac.uk and complete an online application form.  Applicants who would like to receive this advert in an alternative format (e.g. large print, Braille, audio or hard copy), or who are unable to apply online should contact us by telephone on 01793 867003, please quote reference number

Closing date: 8th October 2012

The MRC is an Equal Opportunities Employer

Final appointments will be subject to a pre employment screening.
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Grand Challenge PhD in Rihel Lab at UCL

Posted by on September 11th, 2012

PhD Position
University College London
Department of Cell and Developmental Biology
PhD Supervisor: Dr. Jason Rihel
Application Deadline: Oct. 15, 2012


Funding Availability:  Funding PhD Project (Grand Challenge; European/UK Students; including a stipend of £18,000 a year, Home/EU fees and £5000 per year research funds).  Non-UK/EU citizens are eligible but must have the ability to pay the difference between the Home/EU fee and the International fee for the 3 years.


Sleep is a fundamental biological process that has a major impact on human health, cognitive performance, and quality of life, yet the genetic and neural mechanisms that regulate sleep/wake behaviour are largely unknown. In the Rihel lab, we use zebrafish as a model system to study the regulation of sleep because it combines the powerful genetics of invertebrate models with the basic brain structures that regulate sleep in humans. We use high throughput behavioural assays to measure sleep behaviours in the fish and exploit genetic tools to manipulate critical regulators of sleep, such as the functionally conserved hypocretin/orexin (Hcrt) signalling system.  Recently, we have performed both small molecule and genetic screens to identify potential novel regulators of sleep in zebrafish. 

The successful PhD student will combine cutting edge techniques in molecular biology and behavioural neuroscience to explore the function of novel sleep genes and drugs.  In particular, the research will aim to map the neural circuits that are altered by small molecule and neuropeptide manipulations.       

Applicants should have a degree in molecular biology, neurobiology, or a similar field.  A 2:1 or better is normally required according to UCL eligibility criteria.

Send all enquires to Dr Jason Rihel (j.rihel@ucl.ac.uk).  Applicants should send a CV and names and contact details of two referees.
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Postdoctoral Positions in Cell and Developmental Biology

Posted by on August 7th, 2012

 

POSTDOCTORAL  POSITIONS  in  Cell  an Developmenta Biolog is available to study the cellular and molecular mechanisms controlling the development of the lymphatic vasculature using available mouse models  an its  functiona role in  health  an disease.  Highly motivated individuals who recently obtained a PhD. or MD degree an have  stron backgroun in  molecula an developmental biology are encouraged to apply. Interested individuals should send their curriculum vitae, a brief description of their research interests, and the names of three references to:

 

Guillermo Oliver, Ph.D (guillermo.oliver@stjude.org) Member

Department of Genetics

St. Jude Children’s Research Hospital

332 N. Lauderdale

Memphis, TN 38105

USA

www.stjude.org/departments/oliver.htm
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Postdoctoral Position on WNT signaling in craniofacial development, University of British Columbia, CANADA

Posted by on July 15th, 2012

A postdoctoral position is available immediately in the Richman lab to investigate the function of non-canonical Wnt signaling during craniofacial development in the avian embryo.  Our lab has developed new tools in which to visualize cell organization in post-migratory neural crest-derived mesenchyme (Geetha-Loganathan et al. 2011, Dev Dyn 240:2108–2119). Approaches used will include in vivo grafting to the face, static and time-lapse confocal microscopy,l micromass culture and expression profiling of cells with perturbations of the non-canonical signaling pathways. This project will lead to the discovery of the morphogenetic mechanisms underlying species specific form as well as the basis for human craniofacial abnormalities. UBC has new core facilities for 3D imaging including Optical Projection Tomography, tunable laser confocal microscopy and μCT. Applicants should have recently completed a PhD (2 years or less) and have related research experience in developmental biology and/or cell biology. Salary support is available from research grants but applicants will be encouraged to apply for independent support. Please email a CV, statement of research interests and contact information for three referees to:


Dr. Joy Richman,


Life Sciences Institute, UBC,


2350 Health Sciences Mall,


Vancouver, British Columbia, V6T 1Z3,


CANADA


richman@dentistry.ubc.ca


http://www.dentistry.ubc.ca/research/researchers/Richman/

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Fast times at MBL

Posted by on June 19th, 2012

Sitting down to write this reflection, it struck me that I couldn’t believe it has really been two weeks since I arrived in the quiet town of Woods Hole, MA for the Embryology course at the Marine Biological Laboratory (MBL). Time has become an abstract concept for my fellow students and me; it seems like we just got here and yet have known one another for months. We engage in science almost every hour of every day. There is no work – only play. I was imaging immunostained plankton on a new Nikon A1 confocal microscope at 3am Saturday morning. I would have gone all night except I did not want to miss Nipam Patel’s famous butterfly lecture at 9am the same morning. Again, this isn’t work. I want to be doing this – and so does everyone else here.

I don’t know what generates the enthusiasm and energy at the MBL. In my graduate lab back at the University of Washington I am a hard worker, yet I don’t have the inclination (or ability) to maintain the pace that I have picked up here. It is not uncommon to work in lab until 2 or 3am, and yet we all eagerly attend lectures a few hours later and put in another 15+ hour day, six or seven days a week. Perhaps it’s the access to the best scientific equipment around – the sheer quantity of reagents and quality of microscopes available to us is stunning. However, more likely it’s being removed for six weeks from my regular graduate school environment. There is no pressure to generate actual data during my time here, no PI to disappoint, no lab meetings to prepare, and certainly no time to read current papers (I’ll have a lot of catching up to do in August!). There is only active experimentation. I am encouraged to ask my own questions and take ridiculous risks. I can do what interests me, even if there is no apparent face value for my field. For example, I spent last week honing my antibody staining skills by asking the question, “What is the prettiest combination of antibodies one can use on Drosophila embryos?” At the same time there is enough structure to ensure that I am learning the principles of developmental biology at an alarming pace.

I am a student of molecular biology but fairly new to the field of development, so I initially worried that I would struggle to keep up with students who were already experienced in developmental biology. These worries were unfounded as we all have as varied scientific backgrounds as our countries of origin. As one of five Americans in our class of twenty-four, this experience has allowed me to discover the commonalities in the language of science. Our techniques and questions might be different, but our curiosity and passion is matched. We were told that we would form bonds that will last the rest of our careers here, and two weeks in, I have little doubt that this was the truth.

When we are not actively manipulating embryos, world-renowned scientists distill their experience into our exhausted minds. We absorb as much as we can and then teach them drinking games in the wee hours of the morning. We have learned how to operate multitudes of imaging systems and practiced performing essential experimental techniques on more organisms than most people experience in a lifetime. In just two weeks we have been immersed in the history and current research directions of several models of development, including sea urchin, C. elegans, Drosophila, and many other invertebrates. Each model brings with it new opportunities and excitement, as well as traditions and challenges.

As we make the transition to vertebrate models, I am glad to take this moment to pause and reflect on my experiences so far. Six weeks is a long time to step out of one’s graduate research (and not to mention one’s life). It’s hard to assess what this time will mean to me in the years to come as I continue my own research. But if I were able to continue to engage as fully with the science of life as I have these last two weeks, I would never look back.

 



 

 

 
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