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The people behind the papers #10

Posted by on January 4th, 2017

The tenth paper featured in this series comes from the first issue of Development for 2017, and uses computational modelling to investigate the importance of different cellular processes in spiral cleavage of the early embryo. We caught up with the paper’s first author Miguel Brun-Usan and Isaac Salazar-Ciudad, group leader at the University of Helsinki[…]

The people behind the papers #9

Posted by on December 16th, 2016

The neural crest is a remarkable multipotent cell population that has become a model system for how epithelial cells become mesenchymal and migrate during development. In today’s post, we feature a paper from the recent issue of The Journal of Cell Biology that investigates the role that proteolysis of cell-cell adhesion receptors plays in this process. We caught[…]

An interview with Doug Melton

Posted by on December 15th, 2016

This interview by Aidan Maartens first appeared in Development Volume 143, Issue 24.   Doug Melton is Xander University Professor at Harvard University, co-director of the Harvard Stem Cell Institute and a Howard Hughes Medical Institute Investigator. His lab investigates the development of the pancreas, and uses insights from this process to direct the production[…]

The people behind the papers #8

Posted by on December 14th, 2016

Today’s paper comes from the final issue of Development for 2016, and reveals a link between bioelectricity and reactive oxygen species during tail regeneration in Xenopus. We caught up with first author Fernando Ferreira and his advisor Min Zhao, Professor in Dermatology at UC Davis.     So Min, can you give me the brief history of your[…]

The people behind the papers #7

Posted by on November 30th, 2016

Today’s paper comes from the latest issue of Nature Neuroscience, and shows that in addition to chemical cues, mechanical signals are vital for axon pathfinding during brain development. We caught up with PI Kristian Franze from the Department of Physiology, Development and Neuroscience at the University of Cambridge, and two of the paper’s four lead authors, Amelia[…]

An interview with David McClay

Posted by on November 30th, 2016

This interview by Aidan Maartens first appeared in Development Volume 143, Issue 23.   David McClay is the Arthur S. Pearse Professor of Biology at Trinity College of Arts and Sciences, Duke University, North Carolina. His lab works on the transcriptional control of morphogenesis in the sea urchin embryo. We caught up with David at[…]

The people behind the papers #6

Posted by on November 29th, 2016

Today’s paper comes from the latest issue of Development, and reveals a link between phenotypic variability, cell fate switching and epigenetic silencing in zebrafish. Lead author James T. Nichols, who carried out the work in Charles Kimmel’s lab in Euegene, Oregon and is now an Assistant Professor in UC Denver’s School of Dental Medicine, gave us the story behind[…]

An interview with Kathryn Anderson

Posted by on November 15th, 2016

This interview by Aidan Maartens first featured in Development, Volume 143, Issue 22.    Kathryn Anderson is Professor and Chair of the Developmental Biology Program at the Sloan Kettering Institute in New York. Her lab investigates the genetic networks underlying the patterning and morphogenesis of the early mouse embryo. We caught up with Kathryn at the[…]

An interview with Paola Arlotta

Posted by on November 3rd, 2016

This interview by Catarina Vicente first featured in Development.   Paola Arlotta is a neurodevelopmental biologist based at the Harvard Department of Stem Cell and Regenerative Biology in Boston, MA, USA. Her lab studies the birth, differentiation and assembly of neuronal circuits in the cerebral cortex with the aim of developing novel therapies for degenerative and[…]

The people behind the papers #5

Posted by on October 25th, 2016

So far in this series, we’ve featured fly nuclear pores, lizard tails, squid eyes and mouse digits, and heard from researchers working in Germany, the US and Canada. Today, we switch model system and geographical location once again. The work was published recently in Development, and uses timed inhibition of sonic hedgehog signalling during chick[…]