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An interview with Jenny Nichols

Posted by on August 17th, 2017

This interview by Aidan Maartens originally appeared in Development, Volume 143, Issue 16. Jennifer Nichols is a Principal Investigator at the Cambridge Stem Cell Institute and Department of Physiology, Development and Neuroscience at the University of Cambridge, UK. Her lab works on lineage segregation and the establishment of pluripotency in the mammalian embryo. In 2017 she was[…]

The people behind the papers: Alaa Hachem and John Parrington

Posted by on August 16th, 2017

Embryogenesis begins with fertilisation, and defective activation of the egg by the sperm is implicated in human infertility. Today’s paper, published in the most recent issue of Development, investigates the role of the sperm protein PLCζ in egg activation and the calcium oscillations that accompany it. We caught up with co-first author Alaa Hachem and his[…]

An interview with Jim Smith

Posted by on August 3rd, 2017

To interview Jim Smith I took a train to London and visited the Francis Crick Institute for the first time. The building had opened in 2016 and, by the time I visited, most if not all of the labs had settled in. Architecturally it was quite stunning, especially looking down from one of the higher[…]

The people behind the papers – Giri Dahal, Sarala Pradhan & Emily Bates

Posted by on August 2nd, 2017

Ion channels are famous for their roles in neurons and muscles, but the spectrum of phenotypes seen in ion channel mutants indicate a diversity of roles in development; the underlying mechanisms, however, have remained opaque. This week we feature a paper published in the latest issue of Development that reveals a link between potassium channels and morphogen[…]

Meet Evan Brooks – The 2017 Choose Development! Fellow selected to spend one week with the Embryology Course

Posted by on July 21st, 2017

Evan Brooks is a rising senior at North Carolina State University. For the past two years, he has worked in the lab of Nanette Nascone-Yoder studying the developmental mechanisms of cardiac left-right asymmetry using Xenopus as his model system. Evan was awarded a Choose Development! Fellowship from the Society of Developmental Biology to conduct two[…]

The people behind the papers – Ivette Olivares-Castiñeira & Marta Llimargas

Posted by on July 21st, 2017

The Drosophila tracheal system is a powerful model for understanding the genetic and cell biological control of tubulogenesis. In their new PLoS Genetics paper, Ivette Olivares-Castiñeira and her PI Marta Llimargas of the Molecular Biology Institute of Barcelona connect EGFR signalling to intracellular cell trafficking during tracheal morphogenesis. We caught up with Marta and Ivette to hear the story behind[…]

The people behind the papers – Kimberly McArthur & Joseph Fetcho

Posted by on July 20th, 2017

Development depends on cells coming together in the right place to form functioning tissues. Our latest paper in this series was published recently in Current Biology and asks what happens to the structure and function of the nervous system when motor neuron migration – and hence final position – is disrupted. We caught up with postdoc[…]

An interview with Bill Harris

Posted by on July 6th, 2017

This interview by Aidan Maartens originally appeared in Development, Volume 143, Issue 13.    William ‘Bill’ Harris is Head of the Department of Physiology, Development and Neuroscience at the University of Cambridge, UK, and a Fellow of both the Royal Society and Academy of Medical Sciences. His lab works on the development of the vertebrate[…]

The people behind the papers: Lijun Chi and Paul Delgado-Olguin

Posted by on June 9th, 2017

Development of the placental vasculature – known as the labyrinth – is critical for foetal development. Today’s paper comes from the most recent issue of Development and addresses the signalling events involved in placental vascular maturation. We caught up with lead author Lijun Chi and her PI Paul Delgado-Olguin of the Hospital for Sick Children and University[…]

An interview with Hiroshi Hamada

Posted by on June 5th, 2017

This interview by Katherine Brown first appeared in Development, Volume 144, Issue 11. Hiroshi Hamada is the Director of the RIKEN Center for Developmental Biology (CDB) in Kobe, Japan. His lab focusses on the establishment of left-right asymmetry in the mouse embryo, and the role of cilia in the symmetry-breaking event. Hiroshi’s work has been recognised[…]