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Transposons in Embryo Space – TRACER maps in EMAGE

Posted by on February 9th, 2017

A recent publication in Developmental Biology by (Armit et al., 2017) describes how the TRACER dataset can be spatially compared with in situ hybridisation gene expression profiles.   The TRACER dataset of transposon-associated regulatory sensors (Chen et al., 2013) utilises Sleeping Beauty lacZ transposons that have been randomly integrated into the mouse genome Hundreds of[…]

The 12 GIFs of Christmas

Posted by on December 23rd, 2016

To celebrate the Yuletide, we put together the 12 Development GIFs of Christmas on Twitter, a celebration of the beauty and breadth of developmental biology in endless hypnotic loops that you could watch for ages.   Happy GIFmas!   🎄1/12 @Dev_Journal GIFs of Christmas🎄SPIM #zebrafish, from Bassi, et al. https://t.co/36Kl6A72Ow pic.twitter.com/8NIO1M9t3j — the Node (@the_Node)[…]

From biology to art

Posted by on November 4th, 2016

At the BSDB’s  Autumn Meeting on chimeras, scientist and artist Mia Buehr exhibited some of her art inspired by developmental biology. Here, she introduces her pieces. You can keep up with her work at theaccidentalembroiderer.typepad.com   I was born into a family of artists, and painting and drawing were always second nature to me. However I[…]

Where does blood come from in the first place and how is it made?

Posted by on September 14th, 2016

Commentary on Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells in Developmental Cell, Volume 38, Issue 4, p358–370, 22 August 2016   Each of us has around 6 pints of blood. The blood contains a number of different types of cells, including oxygen-transporting red blood cells, disease-protecting white[…]

#BarBarPlots!

Posted by on August 31st, 2016

(or: how to avoid misleading representations of statistical data)   Recently, a kickstarter project raised more than 3000€ in one month to campaign for banning the wrong usage of bar plots in scientific journals. This demonstrates two important points: a lot of the plots in scientific journals are quite misleading, and, a growing number of[…]

Tackling Differentiated Stem Cell Production

Posted by on August 26th, 2016

This post was originally posted on eurostemcell.org, Europe’s stem cell hub.   by Julia Turan Part of the fascinating potential of stem cells is their ability to provide replacement cells and tissues to treat diseases. In order to do this most effectively, scientists need to be able to create differentiated cells quickly and accurately. However, making[…]

3D mini-brain sheds light on Zika Virus in the brain

Posted by on June 10th, 2016

The Zika virus is making headlines as a major world health crisis linked to a host of neurological conditions. In the cases of microcephaly and Guillain-Barre, the evidence that Zika Virus is the root of the condition is strong enough to be considered causal. Babies born to infected mothers often have microcephaly, a condition that manifests[…]

Cellular conversations

Posted by on June 7th, 2016

We know that cells are the building blocks of our bodies. But they are not like inert wooden blocks. They are complicated tiny machines that communicate with each other to make sure that the many simultaneously occurring processes in our bodies are in order. Stem cells participate in many of these cellular conversations, and a[…]

Visualizing our ‘gut instinct’

Posted by on May 19th, 2016

How on earth do we turn into a living, breathing, singing, speaking being, from just the fusion of two cells? Development is fascinating and mysterious. Stem cells are one component of how this intricate process unfolds, allowing the embryo to not have every type of cell from the start. Imagine if the only way our[…]

New Node banners!

Posted by on May 6th, 2016

As you may have noticed, we have a series of new Node banners (alongside some of our old favourites). As there isn’t really space to give credit to the authors on the banner itself, we thought we would write this short post to give credit where credit is due! Below is the list of the[…]