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Blastoid: the backstory of the formation of blastocyst-like structure solely from stem cells.

Posted by on June 27th, 2018

In our recently published paper1, we showed that mouse stem cells self-organize into blastocyst-like structures, that we termed blastoids. Because blastoids can be generated in large numbers, can be finely manipulated, and implant in utero, they are a powerful tool to investigate the principles of pre- and post-implantation development. Here is the backstory of our[…]

New embryo phenotype data from the DMDD programme

Posted by on June 15th, 2018

Following our latest data release, the DMDD website (dmdd.org.uk) now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb defects and cysts in Col4a2 knockouts and replication of the major features of Meckel syndrome in B9d2 knockouts. We have begun to add immunohistochemistry image[…]

Vote for a Development cover – we have a winner!

Posted by on June 6th, 2018

Two weeks ago we set up our latest competition to vote for an image to adorn the cover of a future Development issue. The images were taken by students of the International Course on Developmental Biology, an EMBO Practical Course held at the Marine Biology Station of Quintay in Chile. Voting has just closed, and with precisely[…]

Vote for a Development cover from the Quintay International Course on Developmental Biology

Posted by on May 23rd, 2018

***We have a winner: go to http://thenode.biologists.com/vote-for-a-development-cover-we-have-a-winner/photo/***     In January, students from across the Americas gathered in Chile to participate in the International Course on Developmental Biology, an EMBO Practical Course held at the Marine Biology Station of Quintay (CIMARQ). In the course of two weeks of intensive training  (you can read a wonderful[…]

A tribute to parrots

Posted by on April 5th, 2018

In a previous blog, I have disgraced parrots by associating them with P-values and discrediting them for their mechanic repetition. Nevertheless, I admire the vivid colours of these multifaceted birds. Here, I want to make it up by dedicating a pseudo-colour look-up table (LUT) to parrots. The images produced by fluorescence microscopy are best displayed[…]

How to win a conference prize

Posted by on December 11th, 2017

Or, at least, produce nice posters while trying. Students on average author 1-3 papers and produce at least three times that many conference posters***. At large meetings, such as the ASCB, thousands of posters are presented each year. While presenting posters is popular, posters sessions evoke mixed feelings: they are often late in the evening,[…]

Allometry in a Simple Cell Network

Posted by on September 19th, 2017

A post by Jasmin Imran Alsous, on work done in collaboration with Paul Villoutreix and Alexander M. Berezhkovskii in the Shvartsman lab. I started working on Drosophila egg chambers from the day I joined the Shvartsman lab. Egg chambers are small clusters of cells that eventually develop into mature oocytes in the abdomen of the female[…]

What Illustrators See that a Camera Can’t

Posted by on August 29th, 2017

Illustrator Natalya Zahn on the role of observation and visual interpretation in her work creating an addendum to Nieuwkoop and Faber’s classic Normal Table of Xenopus laevis   As an artist of science and nature subjects, I’m often asked what makes the work I do better than a photograph. It makes perfect sense to imagine that a[…]

Scales in scientific images

Posted by on August 6th, 2017

I recently saw drawings by Maria Sybilla Merian at Kupferstichkabinett Berlin and the University Library Dresden. Merian, who lived from 1647 to 1717, is renowned for her exceptional illustrations of biological specimens and gained recognition as a scientist for her nature observations, for example, of insect metamorphosis.     Merian evidently was genius in choosing[…]

Four recent science art & photography announcements

Posted by on July 13th, 2017

Worm art at #Worm17 Each year at the International C. elegans Conference Ahna Skop organises a Worm Art Show with winners selected by the meeting participants (find out more about the history of the show here).  2017’s winners have just been announced – read about them over at the GSA’s Genes to Genomes blog (a great site for your bookmarks[…]