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In Development this week (Vol. 143, Issue 20)

Posted by on October 18th, 2016

Here are the highlights from the new issue of Development:   Glucocorticoid and STAT3: tipping the balance in the lung The epithelial cells found at the distal tips of the developing lung comprise a multipotent progenitor population. During development, these cells first give rise to bronchiolar cells, which form the conducting airways, but then switch[…]

Staff Scientist/Research Assistant II – Pluripotent Stem Cells and Cartilage Biology

Posted by on October 10th, 2016

We are looking for an enthusiastic and highly motivated Staff Scientist or experienced Research Assistant/Technician to join the stem cell and regenerative medicine-based laboratory of Dr. April Craft, within the department of Orthopaedic Research at Boston Children’s Hospital and Harvard Medical School. Our lab studies the development of musculoskeletal tissues, primarily articular cartilage, using human[…]

Post-doctoral Position available – Cartilage Development and Disease, Pluripotent stem cells

Posted by on October 10th, 2016

We are looking for an outstanding, highly motivated postdoctoral fellow to join our innovative young department in the stem cell and regenerative medicine-focused laboratory of Dr. April Craft, Assistant Professor of Orthopaedic Surgery at Boston Children’s Hospital and Harvard Medical School. Our lab studies the development of musculoskeletal tissues, primarily cartilage, using human and mouse[…]

In Development this week (Vol. 143, Issue 19)

Posted by on October 4th, 2016

Here are the highlights from the current issue of Development:   Defining digit number in the limb During vertebrate limb development, multiple mechanisms act to ensure the appropriate number, identity and positioning of digits. In both the chick and the mouse, Sonic hedgehog (Shh) signalling emanating from the posterior polarising region provides positional information and[…]

Turning lemons into lemonade…sick planarians reveal link between microbiome and regeneration

Posted by on September 30th, 2016

Commentary on Pathogenic shifts in endogenous microbiota impede tissue regeneration via distinct activation of TAK1/MKK/p38 in eLife 2016; 5: e16793 DOI:   During our research as biologists we endure numerous problems, failures, and setbacks in our efforts to advance scientific knowledge. But sometimes the very problems we encounter are opportunities in disguise. This was[…]

New Technology in Medicine

Posted by on September 22nd, 2016

Technology is quickly changing many parts of medicine, giving people more power to take charge of their health care. Taking isotope labeled peptides as an example, stable isotope labeled peptides have been widely applied in the nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS). The combination of SIL peptides with NMR spectroscopy allow for[…]

Where does blood come from in the first place and how is it made?

Posted by on September 14th, 2016

Commentary on Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells in Developmental Cell, Volume 38, Issue 4, p358–370, 22 August 2016   Each of us has around 6 pints of blood. The blood contains a number of different types of cells, including oxygen-transporting red blood cells, disease-protecting white[…]

In Development this week – Special Issue on Plant Development

Posted by on September 13th, 2016

The current issue of Development – our ‘Special Issue on Plant Development’ – contains a collection of review- and research-based articles focusing on plant development.   Below, you can find details of the review-based articles in this Special Issue:   Plant development: a Special Issue Ottoline Leyser introduces this Special Issue focusing on plant developmental biology,[…]

Postdoctoral position in mammalian retinal development, University of California, Davis

Posted by on September 10th, 2016

A postdoctoral position is available in the laboratory of Nadean Brown to study the role of bHLH transcription factors and Notch signaling during prenatal optic nerve head formation. Highly motivated and creative applicants are encouraged to apply. A Ph.D. in the life sciences is required. Strongest consideration will be given to applicants with formal backgrounds[…]

A Tale of Trunks or Zen and the art of doing a PhD

Posted by on September 1st, 2016

The story of this paper is also the story of my PhD. It begins as most papers and PhDs do: with a distinct and often unrelated starting project or plan. It is great to have a plan. But time and luck and data bend and twist the plan; until it finally breaks and you end[…]