the community site for and by developmental biologists
the community site for and by developmental biologists
Posted by the Node on June 21st, 2017
Here are the highlights from the current issue of Development: Btbd7 branches out across multiple organs Dynamic changes in epithelial cell-cell adhesion and motility are crucial for branching morphogenesis – the process by which highly branched epithelial organs, such as the lung and kidney, grow and develop from a simple epithelial bud. Although many[…]
Posted by Reena Lasrado on June 16th, 2017
Insight into the organizational structure of a growing tissue is imperative for understanding its development and function. Structure can reveal the systematic steps undertaken towards making specific positional and cell fate choices/decisions. A well-defined structure helps to dissect the complexity underlying the networks that form as the tissue develops. It helps to elucidate the foundation[…]
Posted by areilein on June 16th, 2017
A discussion of “Alternative direct stem cell derivatives defined by stem cell location and graded Wnt signalling,” Nat Cell Biol, 2017. 19(5): p. 433-444. We have recently revised the model of Follicle Stem Cell (FSC) organization in the Drosophila ovary, showing that there is a much larger population of stem cells than formerly realized, that[…]
Posted by LANE on June 7th, 2017
One of the research topics in Michel Milinkovitch’s laboratory (https://www.lanevol.org) at the University of Geneva (Switzerland) is to understand how squamates (lizards and snakes) generate such a tremendous variety of colours and colour patterns. Colours The colour of a lizard’s patch of skin is generally the result of the combination among structural and[…]
Posted by the Node on May 30th, 2017
Here are the highlights from the current issue of Development: Getting MAD in meiosis In meiosis I, homologous chromosomes must pair and form crossovers to ensure appropriate chromosome alignment and segregation. During this process, as in mitosis, the spindle assembly checkpoint (SAC) functions to detect misaligned chromosomes at metaphase. This delays anaphase to enable[…]
Posted by Samjbutler on May 16th, 2017
The canonical model The publication of Marc Tessier-Lavigne’s seminal Cell papers (1, 2) in 1994 describing the identification of netrin1 (from the Sanskrit word, netr, meaning “one who guides”) was a defining moment in my graduate career. My friends and I talked about those papers for weeks, from the incredible technical feat, the biochemical purification[…]
Posted by Mubarak Hussain Syed on May 16th, 2017
http://around.uoregon.edu/content/study-brain-formation-finds-possible-link-human-disease @ http://www.doelab.org/ elife https://elifesciences.org/content/6/e26287 (No Ratings Yet) Loading…
Posted by the Node on May 16th, 2017
Here are the highlights from the current issue of Development: A new model for lineage segregation Lineage segregation during gastrulation has long been thought to be driven by differential cell adhesion and cortical tension among cells, which would together lead to a differential tissue surface tension (TST) and the spatial segregation of specific cell types.[…]
Posted by van_cmorr on May 16th, 2017
“It finally got accepted!”, followed by “It’s finally out!” about a month later. I am certain this ‘finally’ feeling about their paper is very familiar to those well-acquainted with the peer review process, and it was no different for our recently published Resource article. The ‘biotagging paper’, as we call it within the Sauka-Spengler lab,[…]
Posted by Ignacio Monedero on May 5th, 2017
Comment on “Anterior-Posterior Gradient in Neural Stem and Daughter Cell Proliferation Governed by Spatial and Temporal Hox Control”, Current Biology 27, 1161-1172 (2017). Ignacio Monedero, Behzad Yaghmaeian, Stefan Thor. Department of Clinical and Experimental Medicine, Linkoping University, Sweden. How cells are generated in proper numbers in order to form specific structures in an organism[…]
