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Life changing experiences with Embryos

Posted by on July 18th, 2018

It’s hard to describe with words how my experience has been at the Marine Biological Laboratory (MBL) in Woods Hole, Massachusetts, but I’m going to give it a try… My attendance at the 2018 Embryology course at the MBL, has been possible thanks to an award I won in my home country, during the International[…]

Differentiating cells mechanically limit progenitor cells’ interkinetic nuclear migration to secure apical cytogenesis

Posted by on July 17th, 2018

Press release for Yuto Watanabe, Takumi Kawaue and Takaki Miyata‘s new Development paper   Key Points Developing brains use a mechanism like the Otoshi-buta (the drop lid), a kitchen wisdom. Differentiating cells in embryonic cerebral walls form a dense filter-like layer to mechanically barrier nuclei of neural stem cells. Loss of this barrier or fence results in[…]

Postdoctoral Position in Cardiovascular Development

Posted by on July 16th, 2018

A postdoctoral position is available in the laboratory of Dr. Sophie Astrof at Thomas Jefferson University to study roles of cell-extracellular matrix (ECM) interactions in cardiovascular development and congenital heart disease. We have recently discovered that progenitors within the second heart field (SHF) give rise to endothelial cells composing pharyngeal arch arteries. Projects in the[…]

A day in the life of a Capitella teleta lab

Posted by on July 10th, 2018

It’s undoubtedly the middle of summer here in Saint Augustine, Florida. Daily temperatures are soaring into the 90s, and we’re grateful if the humidity dips below 70%. Thankfully, the Seaver lab doesn’t have to contend with much of this heat. Instead, our members are inside, comfortable though busier than ever, mentoring summer interns, piloting new[…]

All beauty must die

Posted by on July 9th, 2018

Anna Daneva, Zhen Gao and Moritz Nowack tell the story behind their recent paper in Nature Plants   The transience of flowers is proverbial. Degeneration of flowers is elicited after successful pollination by the onset of seed and fruit development. However, also unpollinated flowers do not last forever – on the contrary, the life span[…]

C. elegans Development, Cell Biology and Gene Expression and 2018 European Worm Meeting report

Posted by on July 9th, 2018

I recently attended the biennial Development, Cell Biology and Gene Expression C. elegans Meeting, this time in combination with the 2018 European Worm Meeting, in Barcelona. C. elegans meetings are always pretty special, defined more than anything else by the strong sense of community between researchers, or, as well like to call ourselves, ‘Worm People’.[…]

Stem cell makes its own niche: the story behind the paper

Posted by on July 7th, 2018

In our recent paper published in Nature, we unravel a new mechanism of an extracellular matrix protein secreted by muscle satellite (stem) cells, thereby playing the unusual role of acting as a signaling molecule to maintain the stem cell population. Here, I share the story behind this discovery and discuss the questions related to niche[…]

It’s alive! But what is it?

Posted by on July 5th, 2018

Iain Martyn & Tatiane Kanno share their experiences of the discovery of the human organizer   “It’s alive!”     Iain’s first impressions   “Hybrid human chicken embryos: HALF HUMAN – HALF CHICKEN abomination created in US lab” was my favourite headline reporting on our work1.  While the headline and accompanying article managed to miss the[…]

How do pigment cells wander around?

Posted by on June 29th, 2018

The story behind melanocyte BACE2, posted by Yan Zhang and Richard White. You can read our recently published full article at Developmental Cell using this link.   Our story began six years ago when my mentor, Dr. Richard White, opened the zebrafish facility and showed me those swimming creatures. He pointed to one type with pigmented[…]

Adult Neurogenesis 2018: Highlights -By Zubair Ahmed Nizamudeen

Posted by on June 29th, 2018

4WH Neurogenesis: What Where Why When and How? Neurogenesis is understood as the process by which neural stem cells (NSCs) produce new neurons. In the adult mammalian brain, this process is known to persist in two restricted locations- the dentate gyrus (DG) region of the hippocampus (see figure below) and the lateral walls of the[…]