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EDRC 2015 Meeting report: “Ich hab mein Herz in Heidelberg verloren”

Posted by on October 8th, 2015

Hundreds of fly researchers from Europe and around the world gathered in the picturesque German city of Heidelberg to attend the European Drosophila Research Conference or EDRC. The local organizers held the meeting at the beautiful historic “Stadthalle”(City Hall) of Heidelberg. I will briefly highlight some of the work that was presented at this meeting,[…]

The Hippo effector YAP in retinal stem cells

Posted by on October 7th, 2015

Xenopus represents a prime model for dissecting in vivo the signalling network that controls retinal stem cell behaviour. Its retina indeed retains a reservoir of active neural stem cells in a peripheral region, the ciliary marginal zone (CMZ), that sustains continuous eye growth throughout life. To identify regulatory mechanisms underlying retinal stem cell activity in[…]

In Development this week (Vol. 142, Issue 19)

Posted by on October 6th, 2015

Here are the highlights from the new issue of Development:   Hormone-mediated flower development: a HEC of a job Fruits originate from the female reproductive part of the flower, the gynoecium, the development of which is controlled by the phytohormones auxin and cytokinin, with evidence for the latter just emerging. HECATE bHLH transcription factors are[…]

EmbryoMaker: a general modeling framework to simulate developing systems and perform experiments in silico.

Posted by on October 4th, 2015

One of the main challenges of Developmental Biology is to understand the complex developmental mechanisms giving rise to different organs or whole organisms. In most cases, these involve the interplay between cell-cell signalling and cell and tissue movements driven by one or several cell behaviours (such as cell proliferation, cell migration, etc.). Cell signalling will[…]

From our sister journals- September 2015

Posted by on September 28th, 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.           Auditory hair cell defects in Wolf-Hirschhorn syndrome Wolf-Hirschhorn syndrome (WHS) is a rare genetic disorder associated with sensorineural deafness. In this study, Andrea Streit and colleagues show that, although cochlear hair cells are specified normally[…]

PLM10: the Physics of Living Matter is coming of age

Posted by on September 27th, 2015

This week, Cambridge (UK) hosted the 10th Symposium on the Physics of Living Matter (PLM10) ( For those of us who were at PLM1, it is surprising to see that what was (and remains) a grass roots organized event, persists. In some ways it is a tribute and an example that a community can be[…]

“Eppur (non) si muove”: why cellular movements may not be essential to the formation of Turing patterns in biology.

Posted by on September 23rd, 2015

D. Bullara* and Y. De Decker *   When Catarina Vicente (Community Manager of “The Node”) proposed us to write a post about our recent paper on pattern formation in zebrafish [Bullara2015] we were very glad for the opportunity she was giving us to tell the background story about our work in this blog. We[…]

In Development this week (Vol. 142, Issue 18)

Posted by on September 22nd, 2015

Here are the highlights from the current issue of Development – our Special Issue on “Human Development”. This Special Issue brings together a collection of Reviews and Research Articles that directly address a broad range of topics in human developmental biology: from the earliest stages of human development to cellular ageing and degeneration, and from basic[…]

Novel mouse alleles allow for sequential mutagenesis using the dual recombinase technology

Posted by on September 20th, 2015

Genetically engineered mouse models have been used extensively to study a wide variety of biological processes in vivo, and innovations in genetic engineering have made it possible to dissect more intricate biological questions. For example, the first mice that showed successful germline transmission of foreign DNA were created in the 1980s, and this allowed the[…]

A technique dating back to 1935 is recovered for cancer research in flies

Posted by on September 15th, 2015

A study conducted by ICREA researcher Cayetano González, at the Institute for Research in Biomedicine (IRB Barcelona), and published in Nature Protocols describes a forgotten technique used in the fly Drosophila melanogaster dating back 80 years. This method allows the transplantation of tissue from larvae to adult flies, thus allowing research into tumour growth and[…]