the community site for and by developmental biologists
the community site for and by developmental biologists
Posted by BKragesteen on November 19th, 2018
Written and illustrated by: Bjørt K. Kragesteen, Malte Spielmann, and Guillaume Andrey. In early development, the forelimb and hindlimb buds of tetrapods are morphologically uniform. However, as limb development proceeds, each individual tissue attains a characteristic morphology that ultimately defines the identity of a forelimb (arm) or a hindlimb (leg). How do undifferentiated limbs[…]
Posted by odedm on November 15th, 2018
Newborn babies are a symbol of immense potential, as they can grow up to be become virtually anybody, from an astronaut to the president. It is no secret that throughout life, there are critical junctions in which specific events or decisions can direct us on one path or another. Such events occur in our brains;[…]
Posted by JNMalagon on November 14th, 2018
Juan N. Malagon and Ernest Ho tell the story behind their recent paper in PLOS Computational Biology. In the Larsen lab, we are interested in testing a 50-year old question: How do sex combs rotate in fruit flies? Despite extensive studies of the process using 4D confocal microscopy, there remain many questions about the spatial and[…]
Posted by rorylcooper on November 7th, 2018
Understanding how complex biological patterns arise is a long standing and fascinating area of scientific research. The patterning, or spatial arrangement, of vertebrate skin appendages (such as feathers, hair and scales) has enabled diverse adaptations, allowing animals to both survive and thrive in varied and challenging environments. Such adaptations include temperature control of mammalian hair1[…]
Posted by skulkar9 on October 31st, 2018
Multiple funded positions for Post-Doctoral Fellows and Research Technicians are available to study Enteric Neurobiology at Johns Hopkins University. Together, the K-Lab and the Pasricha Lab study developmental and adult neurobiology of the Enteric Nervous System. We are seeking motivated, and innovative candidates with strong academic background who can be good team-players to join our[…]
Posted by joshua.finkelstein on October 22nd, 2018
By Sera Moon Busse Studying limb regeneration in model organisms is important for the advancement of regenerative medicine in humans. We set out to study regeneration in the hind limbs of the African Clawed Frog Xenopus laevis – this animal is able to regenerate its hind limbs very early in development, but it loses this[…]
Posted by Jeff Rasmussen on October 18th, 2018
Jeff Rasmussen tells the story behind his recent paper from the Sagasti Lab in Dev Cell. This project began as an extension of my earlier postdoc work in Alvaro Sagasti’s lab investigating removal of axon debris following skin injuries in the larval zebrafish [1] and led me into scientific territory that I never anticipated. It[…]
Posted by chrisbonatto on October 15th, 2018
There is a vast amount of information known about how some animals pattern their bodies into repeated segments, especially in the fruit-fly Drosophila melanogaster. However, when compared to other arthropods, there are several characteristics that are derived in the fruit fly. It has a very short development time, a syncytium at the blastoderm stage allowing[…]
Posted by spagnoli on October 12th, 2018
A Postdoctoral position is available in the Spagnoli lab. in the Centre for Stem Cell and Regenerative Medicine at King’s College, London. Our team uses interdisciplinary approaches to study pancreas development and stem cells. The candidate will be part of an exciting EU-funded FET-Open consortium aiming at bioengineering pancreatic tissue. Developing therapies for pancreatic diseases,[…]
Posted by Joachim Goedhart on October 8th, 2018
Calculation and reporting of p-values is common in scientific publications and presentations (Cristea and Ioannidis, 2018). Usually, the p-value is calculated to decide whether two conditions, e.g. control and treatment, are different. Although a p-value can flag differences, it cannot quantify the difference itself (footnote 1). Therefore, p-values fail to answer a very relevant question:[…]
