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Question Of The Month- developmental biology funding

fly circus squared

Outreach activity: The Disgustovision Show, a most gruesome microscopy circuit

Node survey Q1

The Node survey- the results

axolotl squared

A day in the life of an Axolotl lab

The small beginnings of gastruloids

Posted by on April 1st, 2015

Mouse embryonic stem cells (mESCs) are by definition cells that can self-renew (make identical copies of themselves) and specialize into any cell type of the body. Since their discovery, scientists have used them to produce various specialized cell types in culture but also to produce transgenic mouse lines. When injected into a mouse early embryo, […]
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Report on GUDMAP Outreach at ISN World Congress of Nephrology (ISN WCN)

Posted by on March 30th, 2015

Report on GUDMAP Outreach at ISN World Congress of Nephrology (ISN WCN) March 13-17, 2015 Cape Town, South Africa Author: Chris Armit Date: 23rd March 2015 Introduction The International Society of Nephrology (ISN) holds biennial meetings throughout the world, and this was the first ISN WCN to be held in Africa. There was attention brought […]
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In Development this week (Vol. 142, Issue 7)

Posted by on March 24th, 2015

Here are the highlights from the current issue of Development:   ActivinA-ting spiny neuron production from hPSCs The medium-sized spiny neurons, the main projection neurons of the striatum, are generated in the lateral ganglionic eminence (LGE) and degenerate in the early stages of Huntington’s disease (HD) – for which no pharmacological treatment is yet available. […]
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In Development this week (Vol. 142, Issue 6)

Posted by on March 10th, 2015

Here are the highlights from the current issue of Development:   Dmrt1: a common thread in sex determination Dmrt1 and its related genes play a key role in sex determination in a broad range of metazoan species. However, Dmrt1 has become dispensable for testis determination in mammals, and this function is instead carried out by […]
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In Development this week (Vol. 142, Issue 5)

Posted by on February 24th, 2015

Here are the highlights from the current issue of Development:   pancRNAs in early development Promoter-associated noncoding RNAs (pancRNAs) are a class of long noncoding RNAs, transcribed from bidirectional promoters and thought to be involved in promoting expression of the gene transcribed from the opposite strand. Takuya Imamura and colleagues (p.910) now set out to […]
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How to eradicate an organ

Posted by on February 11th, 2015

 Phreatichthys andruzzii, lateral view (left), frontal view (right) Adaptations of some fish species to their environment can be most peculiar, especially within cave dwelling kinds. The so called troglomorphisms slowly turn these fish into almost grotesque looking creatures with no eyes, lost pigments and no scales on the one hand, but with enhanced alternative sensory […]
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In Development this week (Vol. 142, Issue 4)

Posted by on February 10th, 2015

Here are the highlights from the current issue of Development:   Pathways to human hypothalamic neurons The dysfunction of hypothalamic neurons is implicated in a number of common diseases, including obesity, hypertension, and mood and sleep disorders. To date, studies of human hypothalamic neurons have been limited due to their inaccessibility, but now (on p. […]
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Specifying stem cells, specifically

Posted by on February 5th, 2015

Bone marrow transplants save lives. It’s as simple as that. The reason bone marrow transplants are so effective is because this squishy tissue is home to haematopoietic stem cells (HSCs), which spend their lives happily producing every single blood cell that will ever circulate around your body. As a result, if anything goes wrong with […]
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BSDB Gurdon Summer Studentship Report (3)

Posted by on February 3rd, 2015

In 2014, the British Society of Developmental Biology (BSDB) has initiated the Gurdon Summer Studentship program with the intention to provide highly motivated students with exceptional qualities and a strong interest in Developmental Biology an opportunity to engage in practical research. The 10 successful applicants spent 8 weeks in the research laboratories of their choices, […]
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Stem cells…now showing in 3D

Posted by on January 22nd, 2015

    Growing organs in vitro is one of the ultimate dreams of any stem cell biologist. As such, it seems obvious that some of these organs will need to be grown in 3D. This is why stem cell 3D culture systems are very fashionable among scientists. They are increasingly successful and a fair amount […]
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