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Midwest Society for Developmental Biology Meeting, October 16-18, 2014

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Of mice and men: exploring Mouse ENCODE

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A Day in the Life of a Turtle lab

Stem cells…now showing in 3D

Posted by on January 22nd, 2015

    Growing organs in vitro is one of the ultimate dreams of any stem cell biologist. As such, it seems obvious that some of these organs will need to be grown in 3D. This is why stem cell 3D culture systems are very fashionable among scientists. They are increasingly successful and a fair amount […]
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In Development this week (Vol. 142, Issue 3)

Posted by on January 20th, 2015

Here are the highlights from the new issue of Development:   Invadosomes: aiding axonal invasion Invasive cells such as immune and metastatic cancer cells form protrusions known as invadosomes, which mediate adhesion to the underlying substrate and induce extracellular matrix degradation – thus promoting invasiveness. On p. 486, Timothy Gomez and colleagues demonstrate that invadosomes […]
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In Development this week (Vol. 142, Issue 2)

Posted by on January 6th, 2015

Here are the highlights from the new issue of Development:   The ‘second brain’: taking gut development up a Notch The vertebrate gastro-intestinal (GI) tract consists of a regionalized epithelial tube surrounded by mesenchyme that later differentiates into smooth muscle. During the early stages of stomach patterning in chick embryos, the primitive GI track is […]
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The rabbit blastocyst modelling (for) vertebrate gastrulation

Posted by on January 5th, 2015

Form and function of animal gastrulation have been longstanding classics accompanying the rise of experimental embryology, and – as if to square the circle in the literal sense – the blastopore of Haeckel’s original ‘gastrea’ stage[1] was soon (and still is) considered analogous to the straight primitive streak of birds and mammals[2-4]. Both forms are […]
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Of mice and men: exploring Mouse ENCODE

Posted by on December 17th, 2014

The Mouse ENCODE Project released a slew of papers late last month reporting findings from a three-year effort to comprehensively map functional elements in the mouse genome. Their major findings are summarized in an integrative paper in Nature (Yue, F. et. al., 2014). Similar to the goals of the human ENCODE project (The ENCODE Project Consortium, […]
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In Development this week (Vol. 142, Issue 1)

Posted by on December 16th, 2014

Here are the highlights from the current issue of Development:   Planar cell polarity squeezes in on the action The planar cell polarity (PCP) pathway regulates the polarization of epithelial tissues in various contexts, but recent studies suggest that the PCP pathway also influences other aspects of morphogenesis. Here, Sergei Sokol and colleagues uncover a […]
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Why Not Publish Your Antibody Validation Data

Posted by on December 15th, 2014

Antibodies are frequently used in developmental biology labs, but their validation is crucial to provide the information needed in order to reliably interpret the results of experiments. Antibody validation is also important to help scientists chose antibodies that will be suitable for their experiments, yet the results of these validations rarely get published. To try […]
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Seeing cells from a different angle

Posted by on December 7th, 2014

Thanks to microscopy, scientists can compete with the most talented photographers and take the most astonishing pictures! Although I have been focusing on microscopy pictures in this blog, microscopy is not the only way to make pretty pictures of cells. In recent years, the rapid progress in sequencing technology has propelled this technique to the […]
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EuroStemCell November 2014 Newsletter: World Diabetes Day

Posted by on December 4th, 2014

Hello! We’d like to start by offering our congratulations to Dr Masayo Takahashi who won 2014 Stem Cell Person of year!  A fitting acknowledgement of her and her team’s, hard work. Also this month we marked World Diabetes Day on the 14th of November with a Twitter campaign and two pieces from the EC-funded HumEn research […]
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Nominations for the 2015 Beddington medal

Posted by on December 1st, 2014

Nominations are invited for the 2015 Beddington Medal for the best graduating PhD student in the field of Developmental Biology. The eligibility period covers PhD dissertations submitted anytime during 2014. The closing date for nominations this year is Wednesday 14th January, 2015. Before submitting any nomination, please read further details here.
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