the community site for and by developmental biologists

An Interview With Ken Zaret

Posted by on September 9th, 2010

(This interview by Kathryn Senior originally appeared in Development on September 7, 2010) Ken Zaret is Joseph Leidy Professor in the Department of Cell and Developmental Biology, the Associate Director of the Institute for Regenerative Medicine, and the Co-Director of the Epigenetics Program at the University of Pennsylvania School of Medicine. He agreed to be[…]

Scheduled down time

Posted by on September 9th, 2010

The server that the Node runs on is going to receive some general maintenance between 6:30 PM UK time tonight and early tomorrow morning. This may affect our visitors in North America (and the early risers at the other end of the Pacific) so please be patient if anything seems to not be working during[…]

the Node update – Jobs

Posted by on September 7th, 2010

New format for job postings You may have noticed some job ads for postdocs appearing on the Node. Until today, these ads appeared with the rest of the posts, but we now changed how job ads are displayed on the Node, to make them stand out from the rest of the content. This makes it[…]

In Development this week (Vol 137, Issue 19)

Posted by on September 7th, 2010

Here are the research highlights from the current issue of Development: Nr5a receptors reset EpiSC pluripotency Rodent embryonic stem (ES) cells that are derived from blastocysts self-renew without mitogenic growth factors and robustly colonize chimaeras, whereas egg cylinder-derived stem cells (EpiSCs) require fibroblast growth factor and contribute poorly to chimaeras. Nevertheless, expression of a single[…]

Recombine to get better

Posted by on September 6th, 2010

Recently a paper in Science caught my attention since its title combines the words mitotic recombination with patients and Ichthyosis. Having worked with Drosophila during my PhD and now being in a vertebrate lab, I’m well aware of the existence of tools to induce mitotic recombination to generate somatic clones of mutant cells in certain[…]

Arabidopsis song

Posted by on September 6th, 2010

“Why are there no pop hits about Arabidopsis?” sings Karmadillo. Even though their Arabidopsis song is not a pop hit (yet?) either, Karmadillo can at least lay claim to the honour of having performed it alongside other science-themed songs on the “Reproductive Stage” at the virtual 2010 Geek Pop festival. The song celebrates Arabidopsis as[…]

BioEYES: Inspiring Youth to Pursue Science

Posted by on September 3rd, 2010

by Valerie Butler Most of us, I’m sure, can remember that AHA moment in school when we realized that science is pretty cool. Imagine how it might be for a student enrolled in a school lacking the resources to teach science well, or who was never given the opportunity to excel in anything, let alone[…]

Evolution of cerebral cortex traced back to Precambrian era

Posted by on September 2nd, 2010

In a paper published today in Cell, Detlev Arendt, Raju Tomer and colleagues reveal evidence that the cerebral cortex evolved much earlier than previously believed. Using a new technique to detect and image simultaneously expressed genes in a compact brain area, they discovered that the gene expression patterns in the olfactory processing region (mushroom bodies)[…]

Phenologs and unlikely models

Posted by on September 1st, 2010

“You’re probably wondering why I’m here”, were the first words of Edward Marcotte’s talk at the SDB meeting last month. After all, he was about to speak about systems biology in a session on organogenesis. What followed was not only a new way to identify genes involved in developmental processes, but also a perfect example[…]

U.S. Judge Halts Federal Funding of Human Embryonic Stem Cell Research

Posted by on August 26th, 2010

Many human embryonic stem cell (hESC) researchers are now scrambling for funding and concerned about the future of their research, following a recent ruling in the United States by Chief Judge Royce C. Lamberth.  To understand this ruling, both how it came about and its implications moving forward, it’s important to take a look at[…]